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BioMedInformatics, Volume 2, Issue 1

March 2022 - 13 articles

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Articles (13)

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Article

6 Citations

16,683 Views

19 Pages

Analysis of Single-Cell RNA-Sequencing Data: A Step-by-Step Guide

Aanchal Malhotra,
Samarendra Das and
Shesh N. Rai

BioMedInformatics2022, 2(1), 43-61;https://doi.org/10.3390/biomedinformatics2010003

26 December 2021

Single-cell RNA-sequencing (scRNA-seq) technology provides an excellent platform for measuring the expression profiles of genes in heterogeneous cell populations. Multiple tools for the analysis of scRNA-seq data have been developed over the years. T...

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Review

3,401 Views

25 Pages

Medical Decision Making for Cardiac MRI with CFD “Detection of Severe Stenosis Using a 5D Model of the Descending Aorta”

Houneida Sakly,
Mourad Said and
Moncef Tagina

BioMedInformatics2022, 2(1), 18-42;https://doi.org/10.3390/biomedinformatics2010002

24 December 2021

The aim of this study is to develop a reliable 5D (x, y, z, time, flow dimension) model for medical decision making. Sophisticated techniques for the assessment of serious stenosis were developed using time-dependent instantaneous pressure gradients...

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Article

79 Citations

13,207 Views

17 Pages

Explainable Artificial Intelligence (XAI) in Biomedicine: Making AI Decisions Trustworthy for Physicians and Patients

Jörn Lötsch,
Dario Kringel and
Alfred Ultsch

BioMedInformatics2022, 2(1), 1-17;https://doi.org/10.3390/biomedinformatics2010001

22 December 2021

The use of artificial intelligence (AI) systems in biomedical and clinical settings can disrupt the traditional doctor–patient relationship, which is based on trust and transparency in medical advice and therapeutic decisions. When the diagnosi...

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