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BioMedInformatics, Volume 2, Issue 1

2022 March - 13 articles

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Articles (13)

  • Review
  • Open Access
8 Citations
9,125 Views
13 Pages

Unobtrusive Monitoring of Sleep Cycles: A Technical Review

  • Juwonlo Siyanbade,
  • Bessam Abdulrazak and
  • Ibrahim Sadek

Polysomnography is the gold-standard method for measuring sleep but is inconvenient and limited to a laboratory or a hospital setting. As a result, the vast majority of patients do not receive a proper diagnosis. In an attempt to solve this issue, sl...

  • Article
  • Open Access
20 Citations
8,269 Views
20 Pages

Previous studies demonstrate the feasibility of predicting obesity using various machine learning techniques; however, these studies do not address the limitations of these methods in real-life settings where available data for children may vary. We...

  • Article
  • Open Access
3 Citations
4,284 Views
15 Pages

The RNA polymerase III–specific TFIIIB complex is targeted by oncogenes and tumor suppressors, specifically the TFIIIB subunits BRF1, BRF2, and TBP. Currently, it is unclear if the TFIIIB subunit BDP1 is universally deregulated in human cancers...

  • Review
  • Open Access
11 Citations
6,043 Views
10 Pages

Deep learning techniques, such as convolutional neural networks (CNNs), generative adversarial networks (GANs), and graph neural networks (GNNs) have, over the past decade, changed the accuracy of prediction in many diverse fields. In recent years, t...

  • Article
  • Open Access
27 Citations
5,718 Views
20 Pages

State-of-the-Art Explainability Methods with Focus on Visual Analytics Showcased by Glioma Classification

  • Milot Gashi,
  • Matej Vuković,
  • Nikolina Jekic,
  • Stefan Thalmann,
  • Andreas Holzinger,
  • Claire Jean-Quartier and
  • Fleur Jeanquartier

This study aims to reflect on a list of libraries providing decision support to AI models. The goal is to assist in finding suitable libraries that support visual explainability and interpretability of the output of their AI model. Especially in sens...

  • Article
  • Open Access
8 Citations
4,140 Views
15 Pages

In clinical practice, every decision should be reliable and explained to the stakeholders. The high accuracy of deep learning (DL) models pose a great advantage, but the fact that they function as black-boxes hinders their clinical applications. Henc...

  • Article
  • Open Access
7 Citations
5,368 Views
18 Pages

The computational electroencephalogram (EEG) is recently garnering significant attention in examining whether the quantitative EEG (qEEG) features can be used as new predictors for the prediction of recovery in moderate traumatic brain injury (TBI)....

  • Brief Report
  • Open Access
6 Citations
4,710 Views
5 Pages

Studies have shown that STK11 mutation plays a critical role in affecting the lung adenocarcinoma (LUAD) tumor immune environment. By training an Inception-Resnet-v2 deep convolutional neural network model, we were able to classify STK11-mutated and...

  • Article
  • Open Access
4 Citations
4,795 Views
15 Pages

Projection of High-Dimensional Genome-Wide Expression on SOM Transcriptome Landscapes

  • Maria Nikoghosyan,
  • Henry Loeffler-Wirth,
  • Suren Davidavyan,
  • Hans Binder and
  • Arsen Arakelyan

The self-organizing maps portraying has been proven to be a powerful approach for analysis of transcriptomic, genomic, epigenetic, single-cell, and pathway-level data as well as for “multi-omic” integrative analyses. However, the SOM method has a maj...

  • Article
  • Open Access
8 Citations
5,268 Views
24 Pages

Curcumin Analogues as a Potential Drug against Antibiotic Resistant Protein, β-Lactamases and L, D-Transpeptidases Involved in Toxin Secretion in Salmonella typhi: A Computational Approach

  • Tanzina Akter,
  • Mahim Chakma,
  • Afsana Yeasmin Tanzina,
  • Meheadi Hasan Rumi,
  • Mst. Sharmin Sultana Shimu,
  • Md. Abu Saleh,
  • Shafi Mahmud,
  • Saad Ahmed Sami and
  • Talha Bin Emran

Typhoid fever caused by the bacteria Salmonella typhi gained resistance through multidrug-resistant S. typhi strains. One of the reasons behind β-lactam antibiotic resistance is -lactamase. L, D-Transpeptidases is responsible for typhoid fever a...

  • Article
  • Open Access
6 Citations
17,266 Views
19 Pages

Analysis of Single-Cell RNA-Sequencing Data: A Step-by-Step Guide

  • Aanchal Malhotra,
  • Samarendra Das and
  • Shesh N. Rai

Single-cell RNA-sequencing (scRNA-seq) technology provides an excellent platform for measuring the expression profiles of genes in heterogeneous cell populations. Multiple tools for the analysis of scRNA-seq data have been developed over the years. T...

  • Review
  • Open Access
3,505 Views
25 Pages

The aim of this study is to develop a reliable 5D (x, y, z, time, flow dimension) model for medical decision making. Sophisticated techniques for the assessment of serious stenosis were developed using time-dependent instantaneous pressure gradients...

  • Article
  • Open Access
83 Citations
13,679 Views
17 Pages

The use of artificial intelligence (AI) systems in biomedical and clinical settings can disrupt the traditional doctor–patient relationship, which is based on trust and transparency in medical advice and therapeutic decisions. When the diagnosi...

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BioMedInformatics - ISSN 2673-7426