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Hemato, Volume 1, Issue 2

2020 December - 4 articles

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Articles (4)

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Article

2,477 Views

9 Pages

Indoleamine 2,3-Dioxygenase Activity Is Increased in Myelodysplastic Syndrome Patients

Kimihiro Yamaguchi,
Soranobu Ninomiya,
Takuro Matsumoto,
Nobuhiko Nakamura,
Hiroshi Nakamura,
Junichi Kitagawa,
Nobuhiro Kanemura,
Takeshi Hara,
Suwako Fujigaki and
Masahito Shimizu
+ 3 authors

Hemato2020, 1(2), 77-85;https://doi.org/10.3390/hemato1020011

11 December 2020

Tryptophan (TRP) metabolism via the indoleamine 2,3-dioxygenase (IDO) subset of the kynurenine (KYN) pathway is one of the most important mechanisms of immune escape in cancer. TRP is converted into several biologically active KYN metabolites. Howeve...

Full Article

Review

5 Citations

5,589 Views

17 Pages

The Management of Hematologic Patients with Bloodstream Infections Due to Multi-Drug Resistant Bacteria: Where Do We Stand? From Antibacterial Prophylaxis to the Treatment of Septic Shock

Carolina Secreto,
Alessandro Busca,
Tommaso Lupia,
Silvia Corcione and
Francesco Giuseppe De Rosa

Hemato2020, 1(2), 60-76;https://doi.org/10.3390/hemato1020010

25 November 2020

Bloodstream infection (BSI) and septic shock represent one of the major limiting factors for the successful treatment of patients affected by hematologic malignancies. During the most recent years we have documented a shift in the epidemiology of bac...

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Article

1 Citations

3,369 Views

11 Pages

Passive Coagulability Assay Based on Coherence-Gated Light Scattering

Mahed Batarseh,
Jose Rafael Guzman-Sepulveda,
Ruitao Wu,
William M. DeCampli and
Aristide Dogariu

Hemato2020, 1(2), 49-59;https://doi.org/10.3390/hemato1020009

20 October 2020

Coagulation monitoring relies on in vitro tests where the clot formation is induced using external stimuli. We report an optical method capable of revealing the propensity of coagulation based solely on the natural dynamics of erythrocytes in whole b...

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Review

4 Citations

5,251 Views

13 Pages

The Next Step for MRD in Myeloma? Treating MRD Relapse after First Line Treatment in the REMNANT Study

Anne-Marie Rasmussen,
Frida Bugge Askeland and
Fredrik Schjesvold

Hemato2020, 1(2), 36-48;https://doi.org/10.3390/hemato1020008

24 September 2020

The treatment approach for multiple myeloma (MM) has changed in recent years. After the approval of maintenance treatment after stem cell transplant in younger patients, the paradigm of continuous treatment is now prevailing in all clinical situation...

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