3.1
Impact Factor
4.8
CiteScore
22 days
Time to First Decision

BioTech, Volume 11, Issue 2

June 2022 - 13 articles

Cover Story: L-asparaginase (ASNase) is an aminohydrolase enzyme with significant applications in the pharmaceutical and food industries, notably in lymphoproliferative disorder treatment and in acrylamide reduction, and a potential carcinogenic compound found in heat-processed food products. However, due to the unstable nature of free enzymes and limitation to a single use, enzyme immobilization is a fascinating prospect to improve their properties. In this work, carbon xerogels with unique advantages, such as tunable size, high surface area, and strong loading capacity, were used for the first time as ASNase immobilization support. The immobilization conditions were optimized using a central composite design methodology, achieving exceptional immobilized ASNase recovered activities and immobilization yields, as well as improved operational and pH stabilities. View this paper

Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
You may sign up for email alerts to receive table of contents of newly released issues.
PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (13)

Select all

Article

15 Citations

4,854 Views

20 Pages

Immobilization and Characterization of L-Asparaginase over Carbon Xerogels

Rita A. M. Barros,
Raquel O. Cristóvão,
Sónia A. C. Carabineiro,
Márcia C. Neves,
Mara G. Freire,
Joaquim L. Faria,
Valéria C. Santos-Ebinuma,
Ana P. M. Tavares and
Cláudia G. Silva

BioTech2022, 11(2), 10;https://doi.org/10.3390/biotech11020010

14 April 2022

L-asparaginase (ASNase) is an aminohydrolase currently used in the pharmaceutical and food industries. Enzyme immobilization is an exciting option for both applications, allowing for a more straightforward recovery and increased stability. High surfa...

Full Article

Article

2 Citations

3,776 Views

19 Pages

Oxidative Stress- and Autophagy-Inducing Effects of PSI-LHCI from Botryococcus braunii in Breast Cancer Cells

Freisa M. Joaquín-Ovalle,
Grace Guihurt,
Vanessa Barcelo-Bovea,
Andraous Hani-Saba,
Nicole C. Fontanet-Gómez,
Josell Ramirez-Paz,
Yasuhiro Kashino,
Zally Torres-Martinez,
Katerina Doble-Cacho and
Louis J. Delinois
+ 2 authors

BioTech2022, 11(2), 9;https://doi.org/10.3390/biotech11020009

30 March 2022

Botryococcus braunii (B. braunii) is a green microalga primarily found in freshwater, reservoirs, and ponds. Photosynthetic pigments from algae have shown many bioactive molecules with therapeutic potential. Herein, we report the purification, charac...

Full Article

Article

32 Citations

4,612 Views

11 Pages

Physiological and Molecular Aspects of Two Thymus Species Differently Sensitive to Drought Stress

Mohsen Ashrafi,
Mohammad-Reza Azimi-Moqadam,
Ehsan MohseniFard,
Farid Shekari,
Hossein Jafary,
Parviz Moradi,
Mariachiara Pucci,
Giulia Abate and
Andrea Mastinu

BioTech2022, 11(2), 8;https://doi.org/10.3390/biotech11020008

23 March 2022

Drought is one of the most important threats to plants and agriculture. Here, the effects of four drought levels (90%, 55%, 40%, and 25% field capacity) on the relative water content (RWC), chlorophyll and carotenoids levels, and mRNA gene expression...

Full Article

of 2

Get Alerted

Add your email address to receive forthcoming issues of this journal.

BioTech - ISSN 2673-6284

Imprint

Download Flyer