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Gastrointestinal Disorders, Volume 3, Issue 4

2021 December - 8 articles

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Articles (8)

  • Review
  • Open Access
5 Citations
7,526 Views
18 Pages

Celiac disease (CD) is a small intestinal inflammatory condition where consumption of gluten induces a T-cell mediated immune response that damages the intestinal mucosa in susceptible individuals. CD affects at least 1% of the world’s populati...

  • Review
  • Open Access
6 Citations
4,240 Views
10 Pages

MicroRNAs as Diagnostic Tools in Hepatocellular Carcinoma

  • Jessica Evangelista,
  • Elisa Zaninotto,
  • Annalisa Gaglio,
  • Michele Ghidini and
  • Lucrezia Raimondi

Liver cancer is the fourth leading cause of cancer-related deaths worldwide, with hepatocellular carcinoma (HCC) accounting for approximately 80% of all liver cancers. The serum concentration of alpha-fetoprotein (AFP) is the only validated biomarker...

  • Article
  • Open Access
1 Citations
6,110 Views
19 Pages

Tribbles Gene Expression Profiles in Colorectal Cancer

  • Mónica T. Fernandes,
  • Victor Yassuda,
  • José Bragança,
  • Wolfgang Link,
  • Bibiana I. Ferreira and
  • Ana Luísa De Sousa-Coelho

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of death due to cancer in the world. Therefore, the identification of novel druggable targets is urgently needed. Tribbles proteins belong to a pseudokinase family,...

  • Article
  • Open Access
1 Citations
3,560 Views
11 Pages

M1 Polarized Tumor-Associated Macrophages (TAMs) as Promising Prognostic Signature in Stage I–II Gastric Adenocarcinomas

  • Antonio Ieni,
  • Rosario Alberto Caruso,
  • Cristina Pizzimenti,
  • Giuseppe Giuffrè,
  • Eleonora Irato,
  • Luciana Rigoli,
  • Giuseppe Navarra,
  • Guido Fadda and
  • Giovanni Tuccari

Tumor-associated macrophages (TAMs) may be noticed in gastric carcinomas (GC), but their clinicopathological significance has not been yet explored. From a histological review of 400 cases of tubular/papillary adenocarcinomas, 24 cases of stage I–II...

  • Review
  • Open Access
16 Citations
7,208 Views
31 Pages

Colorectal Cancer Screening: Have We Addressed Concerns and Needs of the Target Population?

  • Thuy Ngan Tran,
  • Allegra Ferrari,
  • Sarah Hoeck,
  • Marc Peeters and
  • Guido Van Hal

Despite the recognized benefits of colorectal cancer (CRC) screening, uptake is still suboptimal in many countries. In addressing this issue, one important element that has not received sufficient attention is population preference. Our review provid...

  • Review
  • Open Access
3 Citations
4,978 Views
14 Pages

A Survey of Methodologies for Assessing Mast Cell Density and Activation in Patients with Functional Abdominal Pain Disorders

  • Hunter Friesen,
  • Meenal Singh,
  • Vivekanand Singh,
  • Jennifer V. Schurman and
  • Craig A. Friesen

30 September 2021

The aim was to assess methods utilized in assessing mast cell involvement in functional abdominal pain disorders (FAPDs), specifically to describe variability in methods utilized to assess both mast cell density and activation and determine if a cons...

  • Hypothesis
  • Open Access
6 Citations
5,178 Views
17 Pages

30 September 2021

The reduction of excessive weight remains a major public health challenge, with control currently limited to a calorie reduction strategy. Currently, attempts are being made at revisiting the fibre hypothesis based on the African studies of Denis Bur...

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Gastrointest. Disord. - ISSN 2624-5647