Smoking and Lung Cancer

Ewa Jassem; Amelia Szymanowska; Alicja Siemińska; Jacek Jassem

doi:10.5603/ARM.27785

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Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.

Review

12 August 2009

Smoking and Lung Cancer

and

Klinika Alergologii Gdańskiego Uniwersytetu Medycznego, ul. Dębinki 7, 80-211 Gdańsk, Poland

Klinika Onkologii i Radioterapii Gdańskiego Uniwersytetu Medycznego, ul. Dębinki 7, 80-211 Gdańsk, Poland

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Adv. Respir. Med.2009, 77(5), 469-473;https://doi.org/10.5603/ARM.27785

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Abstract

In this review we presented a relation between cigarette smoking and lung cancer. We characterized molecular alterations resulting from carcinogens present in the cigarette smoke and presented the constitutive genetic profiles related to the increased risk of lung cancer. We also discussed a possible use of these profiles in the selection of high risk groups among the heavy smokers. Finally, a positive impact of quitting smoking in lung cancer patients, including those who have undergone curative resection, was presented.

Keywords:

cigarette smoking; lung cancer; gene polymorphism; risk of lung cancer; screening

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