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Tropical Medicine and Infectious Disease, Volume 8, Issue 7

July 2023 - 47 articles

Cover Story: Timely identification, screening and TB preventive therapy (TPT) help in the early diagnosis and prevention of TB among child household contacts of pulmonary tuberculosis patients (PTBP). This cohort study assessed the performance of the TB programme in managing child household contacts (aged <15 years) of PTBP treated in Bishkek, the Kyrgyz Republic. Over 90% of 297 identified child household contacts were screened and active TB was diagnosed in 9%. TPT was initiated in nearly half of those eligible, but in two thirds, it took more than 15 days to initiate TPT. Appreciably, 80% completed TPT. This study from SORT IT on the building operational research capacity of TB programme managers to make evidence-informed decisions recommends that health workers counsel caregivers about the timely initiation of TPT. View this paper
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Articles (47)

  • Article
  • Open Access
8 Citations
2,538 Views
12 Pages
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Improvement in Infection Prevention and Control Compliance at the Three Tertiary Hospitals of Sierra Leone following an Operational Research Study

  • Rugiatu Z. Kamara,
  • Ibrahim Franklyn Kamara,
  • Francis Moses,
  • Joseph Sam Kanu,
  • Christiana Kallon,
  • Mustapha Kabba,
  • Daphne B. Moffett,
  • Bobson Derrick Fofanah,
  • Senesie Margao and
  • Matilda N. Kamara
  • + 5 authors
Trop. Med. Infect. Dis.2023, 8(7), 378;https://doi.org/10.3390/tropicalmed8070378

24 July 2023

Implementing infection prevention and control (IPC) programmes in line with the World Health Organization’s (WHO) eight core components has been challenging in Sierra Leone. In 2021, a baseline study found that IPC compliance in three tertiary...

Full Article
  • Brief Report
  • Open Access
8 Citations
2,963 Views
14 Pages
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One Health Approach in Serosurvey of Toxoplasma gondii in Former Black Slave (Quilombola) Communities in Southern Brazil and Among Their Dogs

  • Giovanni Kalempa Panazzolo,
  • Louise Bach Kmetiuk,
  • Orlei José Domingues,
  • João Henrique Farinhas,
  • Fernando Rodrigo Doline,
  • Danilo Alves de França,
  • Nássarah Jabur Lot Rodrigues,
  • Leandro Meneguelli Biondo,
  • Rogério Giuffrida and
  • Helio Langoni
  • + 3 authors
Trop. Med. Infect. Dis.2023, 8(7), 377;https://doi.org/10.3390/tropicalmed8070377

24 July 2023

Brazilian quilombos are rural semi-isolated remnant communities of former black slaves and their descendants who traditionally maintained themselves through archaic subsistence livestock and agriculture practices and historically lacked specific publ...

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  • Article
  • Open Access
2 Citations
3,263 Views
15 Pages
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Improvement in Infection Prevention and Control Performance Following Operational Research in Sierra Leone: A Before (2021) and After (2023) Study

  • Senesie Margao,
  • Bobson Derrick Fofanah,
  • Pruthu Thekkur,
  • Christiana Kallon,
  • Ramatu Elizabeth Ngauja,
  • Ibrahim Franklyn Kamara,
  • Rugiatu Zainab Kamara,
  • Sia Morenike Tengbe,
  • Matilda Moiwo and
  • Robert Musoke
  • + 9 authors
Trop. Med. Infect. Dis.2023, 8(7), 376;https://doi.org/10.3390/tropicalmed8070376

23 July 2023

Introduction: Infection prevention and control (IPC) is crucial to limit health care-associated infections and antimicrobial resistance. An operational research study conducted in Sierra Leone in 2021 reported sub-optimal IPC performance and provided...

Full Article
  • Article
  • Open Access
5 Citations
2,851 Views
19 Pages
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Anti-Leishmania amazonensis Activity, Cytotoxic Features, and Chemical Profile of Allium sativum (Garlic) Essential Oil

  • Andreza R. Garcia,
  • Mariana M. B. Amorim,
  • Ana Claudia F. Amaral,
  • Jefferson D. da Cruz,
  • Alane B. Vermelho,
  • Dirlei Nico and
  • Igor A. Rodrigues
Trop. Med. Infect. Dis.2023, 8(7), 375;https://doi.org/10.3390/tropicalmed8070375

21 July 2023

Human tegumentary leishmaniasis (HTL) is a serious tropical disease caused by Leishmania amazonensis. Developing new leishmanicidal agents can help overcome current treatment challenges, such as drug resistance and toxicity. Essential oils are a sour...

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  • Article
  • Open Access
4 Citations
2,288 Views
9 Pages
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Molecular Characterization of Staphylococcus aureus Complex Isolated from Free-Ranging Long-Tailed Macaques at Kosumpee Forest Park, Maha Sarakham, Thailand

  • Natapol Pumipuntu,
  • Tawatchai Tanee,
  • Penkhae Thamsenanupap,
  • Pensri Kyes,
  • Apichat Karaket and
  • Randall C. Kyes
Trop. Med. Infect. Dis.2023, 8(7), 374;https://doi.org/10.3390/tropicalmed8070374

20 July 2023

The Staphylococcus (S.) aureus complex, including methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA), and S. argenteus are bacterial pathogens that are responsible for both human and animal infection. However, insight...

Full Article
  • Article
  • Open Access
1 Citations
2,227 Views
12 Pages
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Adherence and Toxicity during the Treatment of Latent Tuberculous Infection in a Referral Center in Spain

  • Juan David Puyana Ortiz,
  • Andrea Carolina Garcés Rodríguez,
  • María Luisa Aznar,
  • Juan Espinosa Pereiro,
  • Adrián Sánchez-Montalvá,
  • Joan Martínez-Campreciós,
  • Nuria Saborit,
  • José Ángel Rodrigo-Pendás,
  • Guadalupe García Salgado and
  • Claudia Broto Cortes
  • + 10 authors
Trop. Med. Infect. Dis.2023, 8(7), 373;https://doi.org/10.3390/tropicalmed8070373

19 July 2023

The screening and treatment of latent tuberculosis infection (LTBI) in countries with a low incidence of TB is a key strategy for the elimination of tuberculosis (TB). However, treatment can result in adverse events (AEs) and have poor adherence. Thi...

Full Article
  • Article
  • Open Access
2 Citations
2,905 Views
12 Pages
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Low Prevalence of Schistosoma mekongi Infection and High Prevalence of Other Helminth Infections among Domestic Animals in Southern Lao People’s Democratic Republic

  • Somphou Sayasone,
  • Phonepadith Khattignavong,
  • Sengdeuane Keomalaphet,
  • Phoyphaylinh Prasayasith,
  • Pheovaly Soundala,
  • Sonesimmaly Sannikone,
  • Takashi Kumagai,
  • Souk Phomhaksa,
  • Phouth Inthavong and
  • Emilie Louise Akiko Matsumoto-Takahashi
  • + 4 authors
Trop. Med. Infect. Dis.2023, 8(7), 372;https://doi.org/10.3390/tropicalmed8070372

18 July 2023

The prevalence of Schistosoma mekongi in humans in the Lao People’s Democratic Republic (Lao PDR) has been relatively well monitored and has decreased due to effective interventions such as preventative chemotherapy with mass drug administratio...

Full Article
  • Case Report
  • Open Access
2,166 Views
8 Pages
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Burying Hatchets into Endemic Diagnoses: Disseminated Blastomycosis from a Potentially Novel Occupational Exposure

  • Kusha Davar,
  • Arthur Jeng and
  • Suzanne Donovan
Trop. Med. Infect. Dis.2023, 8(7), 371;https://doi.org/10.3390/tropicalmed8070371

18 July 2023

Background: Blastomycosis is an endemic fungal disease predominantly observed in the northern regions of North America. It manifests primarily as pulmonary disease but can also involve dissemination to the skin, bones, and genitourinary tract. Detail...

Full Article
  • Review
  • Open Access
1 Citations
3,230 Views
13 Pages
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Seroprevalence and Genotype Diversity of Hepatitis C Virus in the Caribbean—A Review

  • Michelle G. Brown,
  • John F. Lindo,
  • Ivan E. Vickers,
  • Kereann Nelson,
  • Yakima Phillips,
  • Cameil Wilson-Clarke,
  • Samuel Gavi,
  • Gene D. Morse and
  • Andrew H. Talal
Trop. Med. Infect. Dis.2023, 8(7), 370;https://doi.org/10.3390/tropicalmed8070370

17 July 2023

Hepatitis C (HCV) continues to present a global public health challenge, with no vaccine available for prevention. Despite the availability of direct-acting antivirals (DAAs) to cure HCV, it remains prevalent in many regions including the Caribbean....

Full Article
  • Article
  • Open Access
3 Citations
3,944 Views
14 Pages
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Comparing Additionality of Tuberculosis Cases Using GeneXpert or Smear-Based Active TB Case-Finding Strategies among Social Contacts of Index Cases in Nepal

  • Suman Chandra Gurung,
  • Kritika Dixit,
  • Rajan Paudel,
  • Manoj Kumar Sah,
  • Ram Narayan Pandit,
  • Tara Prasad Aryal,
  • Shikha Upadhyay Khatiwada,
  • Govind Majhi,
  • Raghu Dhital and
  • Puskar Raj Paudel
  • + 13 authors
Trop. Med. Infect. Dis.2023, 8(7), 369;https://doi.org/10.3390/tropicalmed8070369

17 July 2023

This study compares the yield and additionality of community-based active tuberculosis (TB) active case-finding strategies using either smear microscopy or GeneXpert as the TB diagnostic test. Active case-finding strategies screened social contacts o...

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