You are currently viewing a new version of our website. To view the old version click .

Tomography, Volume 7, Issue 2

June 2021 - 14 articles

Cover Story: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of upper and lower motor neurons, resulting in muscle atrophy and eventual death. Relaxivity contrast imaging (RCI)-based TRATE has been shown to identify changes to myofiber microstructure. This work aims to demonstrate the potential of MR cystography (MRC) in identifying muscle cytoarchitecture changes among the ALS patient population. Additionally, we highlight the performance of TRATE when compared to existing muscle imaging metrics, and we also demonstrate that the RCI-based approach is more sensitive to monitoring muscle changes when compared to the ALS Functional Rating Scale—Revised (ALSFRS-R) and hand-held dynamometry (HHD) over two visits separated by a period of 6 months. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (14)

  • Article
  • Open Access
43 Citations
5,086 Views
15 Pages

Stability of Radiomic Features across Different Region of Interest Sizes—A CT and MR Phantom Study

  • Laura J. Jensen,
  • Damon Kim,
  • Thomas Elgeti,
  • Ingo G. Steffen,
  • Bernd Hamm and
  • Sebastian N. Nagel

8 June 2021

We aimed to evaluate radiomic features’ stability across different region of interest (ROI) sizes in CT and MR images. We chose a phantom with a homogenous internal structure so no differences for a feature extracted from ROIs of different sizes woul...

  • Article
  • Open Access
2 Citations
12,708 Views
10 Pages

MRI Imaging Characteristics of Glioblastoma with Concurrent Gain of Chromosomes 19 and 20

  • Taejin L. Min,
  • Jason W. Allen,
  • Jose E. Velazquez Vega,
  • Stewart G. Neill and
  • Brent D. Weinberg

2 June 2021

Glioblastoma (GBM) is the most common and deadly primary brain tumor in adults. Some of the genetic variations identified thus far, such as IDH mutation and MGMT promotor methylation, have implications for survival and response to therapy. A recent a...

  • Article
  • Open Access
8 Citations
4,208 Views
9 Pages

31 May 2021

The retromolar canal is an anatomical variation that occurs in the mandibular bone. The retromolar canal typically originates in the mandibular canal on the distal side of the third molar and extends forward and upward to the retromolar foramen (RMF)...

  • Article
  • Open Access
8 Citations
8,841 Views
9 Pages

20 May 2021

The purpose of this study was to compare the scan time, image quality and radiation dose of CT urograms (CTU) using a split vs. single bolus contrast media injection technique. A total of 241 consecutive CTUs performed between August 2019-February 20...

  • Article
  • Open Access
1 Citations
3,116 Views
8 Pages

19 May 2021

Objective: To ascertain non-cardiac abnormality (NCA) incidence in patients undergoing clinical cardiovascular magnetic resonance imaging (CMR) and determine such patients’ clinical importance. Methods: Consecutive patients undertaking CMR study from...

  • Article
  • Open Access
7 Citations
4,323 Views
13 Pages

Vascular Deformation Mapping of Abdominal Aortic Aneurysm

  • Drew J. Braet,
  • Jonathan Eliason,
  • Yunus Ahmed,
  • Pieter A. J. van Bakel,
  • Jiayang Zhong,
  • Zhangxing Bian,
  • Carlos Alberto Figueroa and
  • Nicholas S. Burris

13 May 2021

Abdominal aortic aneurysm (AAA) is a complex disease that requires regular imaging surveillance to monitor for aneurysm stability. Current imaging surveillance techniques use maximum diameter, often assessed by computed tomography angiography (CTA),...

  • Article
  • Open Access
13 Citations
5,290 Views
9 Pages

12 May 2021

Objective: Cardiovascular magnetic resonance imaging (CMR) late gadolinium enhancement technique (LGE) detects thrombus rather than anatomical presence based on tissue properties and is theoretically highly accurate. The present study’s goal was to c...

  • Article
  • Open Access
1 Citations
5,082 Views
11 Pages

Evaluation of Amyotrophic Lateral Sclerosis-Induced Muscle Degeneration Using Magnetic Resonance-Based Relaxivity Contrast Imaging (RCI)

  • Sudarshan Ragunathan,
  • Laura C. Bell,
  • Natenael Semmineh,
  • Ashley M. Stokes,
  • Jeremy M. Shefner,
  • Robert Bowser,
  • Shafeeq Ladha and
  • C. Chad Quarles

(1) Background: This work characterizes the sensitivity of magnetic resonance-based Relaxivity Contrast Imaging (RCI) to Amyotrophic Lateral Sclerosis (ALS)-induced changes in myofiber microstructure. Transverse Relaxivity at Tracer Equilibrium (TRAT...

  • Article
  • Open Access
28 Citations
4,929 Views
15 Pages

A Radiogenomics Ensemble to Predict EGFR and KRAS Mutations in NSCLC

  • Silvia Moreno,
  • Mario Bonfante,
  • Eduardo Zurek,
  • Dmitry Cherezov,
  • Dmitry Goldgof,
  • Lawrence Hall and
  • Matthew Schabath

29 April 2021

Lung cancer causes more deaths globally than any other type of cancer. To determine the best treatment, detecting EGFR and KRAS mutations is of interest. However, non-invasive ways to obtain this information are not available. Furthermore, many times...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,772 Views
15 Pages

Whole-Body [18F]-Fluoride PET SUV Imaging to Monitor Response to Dasatinib Therapy in Castration-Resistant Prostate Cancer Bone Metastases: Secondary Results from ACRIN 6687

  • Mark Muzi,
  • Finbarr O’Sullivan,
  • Timothy G. Perk,
  • John P. Muzi,
  • David A. Mankoff,
  • Robert Jeraj,
  • Fenghai Duan and
  • Evan Y. Yu

25 April 2021

ACRIN 6687, a multi-center clinical trial evaluating differential response of bone metastases to dasatinib in men with metastatic castration-resistant prostate cancer (mCRPC), used [18F]-fluoride (NaF) PET imaging. We extend previous ACRIN 6687 dynam...

of 2

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Tomography - ISSN 2379-139X