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Toxics, Volume 12, Issue 4

2024 April - 74 articles

Cover Story: The safety of drinking water is an important environmental issue with major implications for human health. Boiling is a common household method used to reduce the health risk of water contamination. Here, an integrated approach of in vitro bioassays and non-target analysis was used to reveal changes in endocrine-disrupting activities in tap water samples without and with boiling, and to identify the potential endocrine-disrupting chemicals (EDCs) contributing to these changes. Boiling effectively reduced antagonistic activities against four steroid hormone receptors but increased estrogenic and glucocorticoid activities in drinking water. Four novel potential EDCs, including a UV filter and three natural metabolites of organisms, were identified in the drinking water sample. View this paper
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Articles (74)

  • Article
  • Open Access
2 Citations
2,431 Views
12 Pages

22 April 2024

The sweet potato weevil Cylas formicarius is a notorious underground pest in sweet potato (Ipomoea batatas L.). However, little is known about the effects of cadmium (Cd) stress on weevil biology and resistance to pesticides and biotic agents. Theref...

  • Article
  • Open Access
3 Citations
2,826 Views
17 Pages

Lipid Dysregulation Induced by Gasoline and Diesel Exhaust Exposure and the Interaction with Age

  • Yutong Gao,
  • Xinzhuo Zhang,
  • Xinting Li,
  • Jinsheng Zhang,
  • Zongyan Lv,
  • Dongping Guo,
  • Hongjun Mao and
  • Ting Wang

19 April 2024

Limited knowledge exists regarding gasoline and diesel exhaust effects on lipid metabolism. This study collected gasoline and diesel exhaust under actual driving conditions and conducted inhalation exposure on male young and middle-aged C57BL/6J mice...

  • Article
  • Open Access
14 Citations
3,532 Views
18 Pages

19 April 2024

The present study investigated the reproductive and developmental effects of sex-specific chronic exposure to dietary arsenic in zebrafish. Adult zebrafish (Danio rerio) were exposed to environmentally realistic doses of arsenic via diet [0 (control;...

  • Article
  • Open Access
4 Citations
4,066 Views
14 Pages

Oleanolic Acid Acetate Alleviates Cisplatin-Induced Nephrotoxicity via Inhibition of Apoptosis and Necroptosis In Vitro and In Vivo

  • Bori Lee,
  • Yeon-Yong Kim,
  • Seungwon Jeong,
  • Seung Woong Lee,
  • Seung-Jae Lee,
  • Mun-Chual Rho,
  • Sang-Hyun Kim and
  • Soyoung Lee

18 April 2024

Cisplatin is a widely used anti-cancer drug for treating solid tumors, but it is associated with severe side effects, including nephrotoxicity. Various studies have suggested that the nephrotoxicity of cisplatin could be overcome; nonetheless, an eff...

  • Article
  • Open Access
4 Citations
2,545 Views
15 Pages

Exposure to Microplastics Made of Plasmix-Based Materials at Low Amounts Did Not Induce Adverse Effects on the Earthworm Eisenia foetida

  • Beatrice De Felice,
  • Stefano Gazzotti,
  • Maddalena Roncoli,
  • Eleonora Conterosito,
  • Valentina Gianotti,
  • Marco Aldo Ortenzi and
  • Marco Parolini

18 April 2024

The implementation of recycling techniques represents a potential solution to the plastic pollution issue. To date, only a limited number of plastic polymers can be efficiently recycled. In the Italian plastic waste stream, the residual, non-homogene...

  • Article
  • Open Access
12 Citations
4,741 Views
14 Pages

Monitoring and Risk Assessment of Pesticide Residues in Fishery Products Using GC–MS/MS in South Korea

  • Myungheon Kim,
  • Mihyun Cho,
  • Seo-Hong Kim,
  • Yoonmi Lee,
  • Mi-Ra Jo,
  • Yong-Sun Moon and
  • Moo-Hyeog Im

18 April 2024

The aim of this study was to assess the risk of pesticide contamination in aquaculture and its impact on fishery products. We conducted an assessment of 300 samples collected from nine regions in South Korea, including various types of seafood, such...

  • Article
  • Open Access
3 Citations
2,473 Views
17 Pages

17 April 2024

As an alternative for perfluorooctane sulfonic acid (PFOS), sodium p-perfluorononyloxybenzene sulfonate (OBS) has been widely used in petroleum, fire-fighting materials, and other industries. In order to efficiently and economically remove OBS contam...

  • Communication
  • Open Access
2 Citations
2,600 Views
9 Pages

17 April 2024

Mycotoxin binders, in combination with enzymes degrading some mycotoxins, contribute to feed detoxification. Their use reduces economic losses and the negative impacts of mycotoxins on animal health and productivity in farm animals. The aim of this s...

  • Article
  • Open Access
5 Citations
3,350 Views
14 Pages

17 April 2024

Background: Obesity, a chronic metabolic disorder, is related to cardiovascular diseases, diabetes, cancer, and reproductive disorders. The relationship between obesity and male infertility is now well recognized, but the mechanisms involved are uncl...

  • Article
  • Open Access
10 Citations
6,446 Views
14 Pages

17 April 2024

Environmental justice research has focused on the distribution of environmental inequalities, such as proximity to landfills, across the U.S. and globally. Background: Public health research and environmental health research, specifically, have focus...

  • Review
  • Open Access
18 Citations
10,911 Views
17 Pages

17 April 2024

Bisphenol A (BPA), an acknowledged endocrine disrupter, is easily exposed to humans via food packaging and container. However, a consensus has not been reached on the extent to which BPA exposure affects the reproductive system. We therefore conducte...

  • Article
  • Open Access
7 Citations
2,843 Views
22 Pages

Spatiotemporal Gradients of PAH Concentrations in Greek Cities and Associated Exposure Impacts

  • Irini Tsiodra,
  • Kalliopi Tavernaraki,
  • Georgios Grivas,
  • Constantine Parinos,
  • Kyriaki Papoutsidaki,
  • Despina Paraskevopoulou,
  • Eleni Liakakou,
  • Alexandra Gogou,
  • Aikaterini Bougiatioti and
  • Nikolaos Mihalopoulos
  • + 2 authors

16 April 2024

To study the spatiotemporal variability of particle-bound polycyclic aromatic hydrocarbons (PAHs) and assess their carcinogenic potential in six contrasting urban environments in Greece, a total of 305 filter samples were collected and analyzed. Samp...

  • Article
  • Open Access
2,277 Views
20 Pages

16 April 2024

The capacity of particulate matter (PM) to enhance and stimulate the expression of pro-inflammatory mediators has been previously demonstrated in non-antigen-presenting cells (human bronchial epithelia). Nonetheless, many proposed mechanisms for this...

  • Article
  • Open Access
6 Citations
3,096 Views
13 Pages

16 April 2024

This study aimed to isolate and characterise endophytic bacteria from the pioneer plant Ageratina adenophora in a mining area. Seven strains of metal-resistant endophytic bacteria that belong to five genera were isolated from the roots of A. adenopho...

  • Article
  • Open Access
6 Citations
2,511 Views
23 Pages

Concordance between In Vitro and In Vivo Relative Toxic Potencies of Diesel Exhaust Particles from Different Biodiesel Blends

  • Subramanian Karthikeyan,
  • Dalibor Breznan,
  • Errol M. Thomson,
  • Erica Blais,
  • Renaud Vincent and
  • Premkumari Kumarathasan

16 April 2024

Diesel exhaust particles (DEPs) contribute to air pollution exposure-related adverse health impacts. Here, we examined in vitro, and in vivo toxicities of DEPs from a Caterpillar C11 heavy-duty diesel engine emissions using ultra-low-sulfur diesel (U...

  • Article
  • Open Access
4 Citations
3,104 Views
13 Pages

Urinary Volatile Organic Compound Metabolites Are Associated with Reduced Lung Function in U.S. Children and Adolescents

  • Angelico Mendy,
  • Sara Burcham,
  • Ashley L. Merianos,
  • Tesfaye B. Mersha,
  • Kimberly Yolton,
  • Aimin Chen and
  • E. Melinda Mahabee-Gittens

16 April 2024

(1) Background: Volatile organic compounds (VOCs) are indoor pollutants absorbed by inhalation. The association of several VOCs with lung function in children and adolescents is unknown. (2) Methods: We analyzed 505 participants, 6–17-year-olds...

  • Article
  • Open Access
3 Citations
3,101 Views
15 Pages

Exposure to Molybdate Results in Metabolic Disorder: An Integrated Study of the Urine Elementome and Serum Metabolome in Mice

  • Kun Zhou,
  • Miaomiao Tang,
  • Wei Zhang,
  • Yanling Chen,
  • Yusheng Guan,
  • Rui Huang,
  • Jiawei Duan,
  • Zibo Liu,
  • Xiaoming Ji and
  • Minjian Chen
  • + 4 authors

14 April 2024

The increasing use of molybdate has raised concerns about its potential toxicity in humans. However, the potential toxicity of molybdate under the current level of human exposure remains largely unknown. Endogenous metabolic alterations that are caus...

  • Article
  • Open Access
4,024 Views
11 Pages

13 April 2024

Dimethylcyclosiloxanes (DMCs) are utilized as vital monomers in the synthesis of organosilicon compounds, integral to the manufacture of mobile smart terminal devices. Toxicological studies have revealed potential endocrine-disrupting activity, repro...

  • Article
  • Open Access
13 Citations
3,311 Views
21 Pages

Distribution and Risk Assessment of Organophosphate Esters in Agricultural Soils and Plants in the Coastal Areas of South China

  • Wangxing Luo,
  • Siyu Yao,
  • Jiahui Huang,
  • Haochuan Wu,
  • Haijun Zhou,
  • Mingjiang Du,
  • Ling Jin and
  • Jianteng Sun

12 April 2024

Organophosphate esters (OPEs) are frequently used as flame retardants and plasticizers in various commercial products. While initially considered as substitutes for brominated flame retardants, they have faced restrictions in some countries due to th...

  • Article
  • Open Access
1 Citations
2,476 Views
17 Pages

Rat Hepatocytes Protect against Lead–Cadmium-Triggered Apoptosis Based on Autophagy Activation

  • Junshu Xue,
  • Huimao Liu,
  • Tianyi Yin,
  • Xun Zhou,
  • Xu Song,
  • Yuanfeng Zou,
  • Lixia Li,
  • Renyong Jia,
  • Yuping Fu and
  • Zhongqiong Yin
  • + 1 author

12 April 2024

Lead and cadmium are foodborne contaminants that threaten human and animal health. It is well known that lead and cadmium produce hepatotoxicity; however, defense mechanisms against the co-toxic effects of lead and cadmium remain unknown. We investig...

  • Article
  • Open Access
5 Citations
2,308 Views
12 Pages

12 April 2024

To investigate the mitigative effects of glycyrrhiza extract (GE) and curcumin (CUR) on the antioxidant and immune functions of the Guizhou black goat exposed to cadmium (Cd), 50 healthy Guizhou black goats (11.08 ± 0.22 kg, male, six months o...

  • Article
  • Open Access
3 Citations
2,534 Views
16 Pages

12 April 2024

Biochar materials have garnered attention as potential catalysts for peroxymonosulfate (PMS) activation due to their cost-effectiveness, notable specific surface area, and advantageous structural properties. In this study, a suite of plantain-derived...

  • Article
  • Open Access
22 Citations
5,285 Views
17 Pages

Neurotoxicity of Combined Exposure to the Heavy Metals (Pb and As) in Zebrafish (Danio rerio)

  • Ming Liu,
  • Ping Deng,
  • Guangyu Li,
  • Haoling Liu,
  • Junli Zuo,
  • Wenwen Cui,
  • Huixian Zhang,
  • Xin Chen,
  • Jingjing Yao and
  • Ning Luan
  • + 5 authors

11 April 2024

Lead (Pb) and arsenic (As) are commonly occurring heavy metals in the environment and produce detrimental impacts on the central nervous system. Although they have both been indicated to exhibit neurotoxic properties, it is not known if they have joi...

  • Article
  • Open Access
2 Citations
2,626 Views
15 Pages

11 April 2024

Dihydroxylated polybrominated diphenyl ethers (DiOH-PBDEs) could be the metabolites of PBDEs of some organisms or the natural products of certain marine bacteria and algae. OH-PBDEs may demonstrate binding affinity to thyroid hormone receptors (TRs)...

  • Article
  • Open Access
4 Citations
2,094 Views
16 Pages

11 April 2024

The arsenic adsorption performance of silicon (Si), iron (Fe), and magnesium (Mg) mixed hydrous oxide containing a Si: Fe: Mg metal composition ratio of 0.05:0.9:0.05 (SFM05905) was investigated. SFM05905 was synthesized by the co-precipitation metho...

  • Article
  • Open Access
2 Citations
1,915 Views
13 Pages

11 April 2024

The diffusion of trace elements in mining wastelands has attracted widespread attention in recent years. Vegetation restoration is an effective measure for controlling the surface migration of trace elements. However, there is no field evidence of th...

  • Article
  • Open Access
4 Citations
2,410 Views
16 Pages

Mechanistic Evidence for Hg Removal from Wastewater by Biologically Produced Sulfur

  • Seok-Soon Jeong,
  • Byung-Jun Park,
  • Jung-Hwan Yoon,
  • Mary Beth Kirkham,
  • Jae-E. Yang and
  • Hyuck-Soo Kim

10 April 2024

A significant quantity of biologically produced sulfur (BPS) is generated as a by-product of chemical and biological desulfurization processes applied to landfill gas treatment. The beneficial upcycling of BPS has seen limited use in the environmenta...

  • Article
  • Open Access
5 Citations
2,358 Views
16 Pages

9 April 2024

A wide variety of dyes, such as toluidine blue (TB), are used daily for a multitude of purposes. After use, many of these compounds end up in aqueous effluents, reaching natural environments, including marine environments. The removal of these pollut...

  • Article
  • Open Access
6 Citations
3,143 Views
12 Pages

Altered Sex Ratio at Birth with Maternal Exposure to Dioxins in Vietnamese Infants

  • Noriko Kaneko,
  • Muneko Nishijo,
  • Hoa Thi Vu,
  • Tai Pham-The,
  • Thao Ngoc Pham,
  • Nghi Ngoc Tran,
  • Tomoya Takiguchi and
  • Yoshikazu Nishino

9 April 2024

Excess female births (lower sex ratio at birth) associated with paternal exposure to 2,3,7,8-tetrachlordibenzo-p-dioxin (TCDD) have been reported in Italy. However, no significant effects of maternal TCDD exposure on the sex ratio were reported. We i...

  • Article
  • Open Access
2 Citations
2,675 Views
18 Pages

Oxidative Dissolution Process of Sphalerite in Fe2(SO4)3-O3 System: Implications for Heavy Metals Removal and Recovery

  • Mingtong Zhang,
  • Hongbo Zhao,
  • Yisheng Zhang,
  • Xin Lv,
  • Luyuan Zhang,
  • Li Shen,
  • Liang Hu,
  • Jiankang Wen,
  • Louyan Shen and
  • Xianping Luo

8 April 2024

Metal sulfides in waste rocks and tailings are susceptible to serious soil and water contamination due to the generation of acid mine drainage (AMD) during stockpiling. The hydrometallurgical process is one of the most essential heavy metal remediati...

  • Review
  • Open Access
8 Citations
3,391 Views
25 Pages

Developmental Toxicity of Fine Particulate Matter: Multifaceted Exploration from Epidemiological and Laboratory Perspectives

  • Ruifeng Yan,
  • Danni Ma,
  • Yutong Liu,
  • Rui Wang,
  • Lifan Fan,
  • Qiqi Yan,
  • Chen Chen,
  • Wenhao Wang,
  • Zhihua Ren and
  • Nan Sang
  • + 2 authors

6 April 2024

Particulate matter of size ≤ 2.5 μm (PM2.5) is a critical environmental threat that considerably contributes to the global disease burden. However, accompanied by the rapid research progress in this field, the existing research on developmental...

  • Article
  • Open Access
1 Citations
2,434 Views
14 Pages

Fe-CGS Effectively Inhibits the Dynamic Migration and Transformation of Cadmium and Arsenic in Soil

  • Hongliang Yin,
  • Changzhi Zhou,
  • Junhuan Wang,
  • Mengxue Yin,
  • Zhihao Wu,
  • Ningning Song,
  • Xin Song,
  • Yuxian Shangguan,
  • Zaijin Sun and
  • Hong Hou
  • + 1 author

6 April 2024

The iron-modified coal gasification slag (Fe-CGS) material has excellent performance in purifying heavy-metal-contaminated water due to its good surface properties and adsorption capacities. However, it is unclear whether it can provide long-term sim...

  • Case Report
  • Open Access
2 Citations
4,629 Views
6 Pages

Accidental Aluminum Phosphide Intoxication Successfully Treated with Hyperbaric Oxygen Therapy: A Case Report

  • Michal Hájek,
  • Dittmar Chmelař,
  • Jakub Tlapák,
  • Veronika Rybárová,
  • Peter Ondra and
  • Vladimír Halouzka

5 April 2024

The most common pesticide agents are organophosphates and phosphides, aluminum phosphide (ALP) in particular. ALP is a major cause of suicidal poisoning in many countries. In other countries, the problem of accidental, mainly occupational-related, po...

  • Article
  • Open Access
6 Citations
4,291 Views
17 Pages

A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS)

  • Richard S. Judson,
  • Doris Smith,
  • Michael DeVito,
  • John F. Wambaugh,
  • Barbara A. Wetmore,
  • Katie Paul Friedman,
  • Grace Patlewicz,
  • Russell S. Thomas,
  • Risa R. Sayre and
  • Kelly E. Carstens
  • + 5 authors

5 April 2024

Per- and polyfluoroalkyl substances (PFAS) are widely used, and their fluorinated state contributes to unique uses and stability but also long half-lives in the environment and humans. PFAS have been shown to be toxic, leading to immunosuppression, c...

  • Review
  • Open Access
37 Citations
7,942 Views
121 Pages

The Comet Assay as a Tool in Human Biomonitoring Studies of Environmental and Occupational Exposure to Chemicals—A Systematic Scoping Review

  • Carina Ladeira,
  • Peter Møller,
  • Lisa Giovannelli,
  • Goran Gajski,
  • Anja Haveric,
  • Ezgi Eyluel Bankoglu,
  • Amaya Azqueta,
  • Marko Gerić,
  • Helga Stopper and
  • Andrew Collins
  • + 2 authors

5 April 2024

Biomonitoring of human populations exposed to chemical substances that can act as potential mutagens or carcinogens, may enable the detection of damage and early disease prevention. In recent years, the comet assay has become an important tool for as...

  • Article
  • Open Access
9 Citations
4,249 Views
15 Pages

Crop Contamination and Human Exposure to Per- and Polyfluoroalkyl Substances around a Fluorochemical Industrial Park in China

  • Kairan Xu,
  • Jian Huang,
  • Yufeng Zhang,
  • Xilong Wu,
  • Dan Cai,
  • Guocheng Hu,
  • Yu Li,
  • Zhuobiao Ni,
  • Qingqi Lin and
  • Rongliang Qiu
  • + 1 author

4 April 2024

Due to their significant environmental impact, there has been a gradual restriction of the production and utilization of legacy per- and polyfluoroalkyl substances (PFAS), leading to continuous development and adoption of novel alternatives. To effec...

  • Article
  • Open Access
7 Citations
2,500 Views
15 Pages

Ferulic Acid Derivatives Ameliorate Intestine Barrier Destruction by Alleviating Inflammatory Responses in Dextran Sulfate Sodium-Induced Inflammatory Bowel Disease

  • Yeon-Yong Kim,
  • Gayeong Hur,
  • Hyun-Jae Jang,
  • Seungwon Jeong,
  • Seung Woong Lee,
  • Seung-Jae Lee,
  • Mun-Chual Rho,
  • Sang-Hyun Kim and
  • Soyoung Lee

3 April 2024

Inflammatory bowel disease (IBD), a chronic disorder affecting the colon and rectum, involves the overproduction of pro-inflammatory cytokines causing damage to tight junctions (TJ) in the intestinal epithelial cells and chronic inflammation. The cur...

  • Article
  • Open Access
15 Citations
3,463 Views
13 Pages

2 April 2024

Perfluorooctane sulfonate (PFOS) is a persistent contaminant that has been found globally within the environment. Key data gaps exist in the toxicity of PFOS to marine organisms, especially estuarine species that are crucial to the food web: fish, sh...

  • Article
  • Open Access
21 Citations
3,695 Views
20 Pages

Sustainable Bio-Based Adsorbents for Simultaneous and Efficient Removal of Hazardous Dyes from Aqueous Solutions

  • Dhwani Vara,
  • Stuti Jha,
  • Shweta Bisht,
  • Syed Shahabuddin,
  • Rama Gaur,
  • Suhas and
  • Inderjeet Tyagi

1 April 2024

Dyes provide a notable environmental issue as a result of their intrinsic poisonous and carcinogenic characteristics. An estimated 60,000 metric tons of dyes has been discharged into the environment, leading to a substantial increase in water polluti...

  • Article
  • Open Access
4 Citations
2,589 Views
24 Pages

31 March 2024

Background: Sodic soils are harmful to agricultural and natural environments in Ethiopia’s semi-arid and arid regions, leading to soil degradation and reduced productivity. This study investigated how amendment resources could help improve the...

  • Article
  • Open Access
8 Citations
4,720 Views
14 Pages

Application of β-Cyclodextrin Adsorbents in the Removal of Mixed Per- and Polyfluoroalkyl Substances

  • Elham Abaie,
  • Manish Kumar,
  • Naveen Kumar,
  • Yilang Sun,
  • Jennifer Guelfo,
  • Yuexiao Shen and
  • Danny Reible

31 March 2024

The extensive use of per- and polyfluoroalkyl substances (PFASs) in industrial consumer products has led to groundwater contamination, raising concerns for human health and the environment. These persistent chemicals exist in different forms with var...

  • Article
  • Open Access
1 Citations
2,358 Views
24 Pages

The α4 Nicotinic Acetylcholine Receptor Is Necessary for the Initiation of Organophosphate-Induced Neuronal Hyperexcitability

  • Peter M. Andrew,
  • Wei Feng,
  • Jonas J. Calsbeek,
  • Shane P. Antrobus,
  • Gennady A. Cherednychenko,
  • Jeremy A. MacMahon,
  • Pedro N. Bernardino,
  • Xiuzhen Liu,
  • Danielle J. Harvey and
  • Isaac N. Pessah
  • + 1 author

31 March 2024

Acute intoxication with organophosphorus (OP) cholinesterase inhibitors can produce seizures that rapidly progress to life-threatening status epilepticus. Significant research effort has been focused on investigating the involvement of muscarinic ace...

  • Article
  • Open Access
21 Citations
3,224 Views
19 Pages

Cadmium-Induced Physiological Responses, Biosorption and Bioaccumulation in Scenedesmus obliquus

  • Pingping Xu,
  • Xiaojie Tu,
  • Zhengda An,
  • Wujuan Mi,
  • Dong Wan,
  • Yonghong Bi and
  • Gaofei Song

31 March 2024

Cadmium ion (Cd2+) is a highly toxic metal in water, even at low concentrations. Microalgae are a promising material for heavy metal remediation. The present study investigated the effects of Cd2+ on growth, photosynthesis, antioxidant enzyme activit...

  • Article
  • Open Access
1 Citations
2,006 Views
15 Pages

A Cross-Sectional Analysis Investigating Pregnant Women’s Renal Function and Its Association with Lead and Cadmium Exposures—The DSAN Birth Cohort Study in Recôncavo Baiano, Brazil

  • Eréndira C. Di Giuseppe,
  • Homègnon A. Ferréol Bah,
  • Erival A. Gomes Júnior,
  • Nathália R. dos Santos,
  • Daisy O. Costa,
  • Victor O. Martinez,
  • Elis Macêdo Pires,
  • João V. Araújo Santana,
  • Filipe da S. Cerqueira and
  • José A. Menezes-Filho

30 March 2024

Kidney dysfunction is increasing worldwide and is exacerbated by exposure to toxic metals. Also, pregnancy poses an overload on kidney function. We investigated how blood lead (PbB) and cadmium (CdB) levels were associated with kidney function in pre...

  • Article
  • Open Access
1 Citations
3,335 Views
19 Pages

Battle of the Bites: The Effect of Sewage Effluent Exposure on Mosquitofish Biocontrol of Mosquitoes in Residential Louisiana

  • Emily A. Kane,
  • Shubham V. K. Yadav,
  • Adeline Fogle,
  • Nigel A. D’Souza,
  • Nicholas DeLisi and
  • Kevin A. Caillouët

30 March 2024

Mosquitofish, Gambusia affinis, are eponymous larval mosquito predators. Their ability to colonize and survive in habitats that are uninhabitable by other potential predators allows them to naturally manage larval mosquito populations in most ground...

  • Article
  • Open Access
6 Citations
4,157 Views
13 Pages

Effect of CYP2D6, 2C19, and 3A4 Phenoconversion in Drug-Related Deaths

  • Sanaa M. Aly,
  • Benjamin Hennart,
  • Jean-Michel Gaulier and
  • Delphine Allorge

30 March 2024

Molecular autopsy is a very important tool in forensic toxicology. However, many determinants, such as co-medication and physiological parameters, should be considered for optimal results. These determinants could cause phenoconversion (PC), a discre...

  • Article
  • Open Access
3 Citations
2,259 Views
17 Pages

Natural Pyrethrin-Induced Oxidative Damage in Human Liver Cells through Nrf-2 Signaling Pathway

  • Yun Yang,
  • Xiaoyi Wei,
  • Mengchao Ying,
  • Haiyan Huang,
  • Yijie Sha,
  • Xinyu Hong,
  • Ping Xiao and
  • Gonghua Tao

30 March 2024

Natural pyrethrins (NPs), one kind of bio-pesticide, have been widely used in organic agriculture and ecological environment studies. Studies have shown that NPs may affect the metabolism of rat liver and human hepatocytes; nevertheless, the toxic ef...

  • Article
  • Open Access
5 Citations
2,968 Views
22 Pages

Hormesis, the Individual and Combined Phytotoxicity of the Components of Glyphosate-Based Formulations on Algal Growth and Photosynthetic Activity

  • Szandra Klátyik,
  • Eszter Takács,
  • Attila Barócsi,
  • Sándor Lenk,
  • László Kocsányi,
  • Béla Darvas and
  • András Székács

30 March 2024

The occurrence of the market-leading glyphosate active ingredient in surface waters is a globally observed phenomenon. Although co-formulants in pesticide formulations were considered inactive components from the aspects of the required main biologic...

  • Feature Paper
  • Review
  • Open Access
13 Citations
6,255 Views
23 Pages

Toxicological Effects of Naturally Occurring Endocrine Disruptors on Various Human Health Targets: A Rapid Review

  • Sara Virtuoso,
  • Carla Raggi,
  • Antonella Maugliani,
  • Francesca Baldi,
  • Donatella Gentili and
  • Laura Narciso

29 March 2024

Endocrine-disrupting compounds are chemicals that alter the normal functioning of the endocrine system of living organisms. They can be natural (N-EDCs) or synthetic compounds (S-EDCs). N-EDCs can belong to different groups, such as phytoestrogens (P...

  • Article
  • Open Access
4 Citations
3,977 Views
15 Pages

Embryotoxicity Induced by Triclopyr in Zebrafish (Danio rerio) Early Life Stage

  • Ítalo Bertoni,
  • Bianca Camargo Penteado Sales,
  • Cristina Viriato,
  • Paloma Vitória Lima Peixoto and
  • Lílian Cristina Pereira

29 March 2024

Triclopyr, an auxin-like herbicide that is widely employed for managing weeds in food crops and pastures, has been identified in various environmental settings, particularly aquatic ecosystems. Limited understanding of the environmental fate of this...

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Toxics - ISSN 2305-6304