Skip to Content
You are currently on the new version of our website. Access the old version .

Separations, Volume 8, Issue 10

2021 October - 33 articles

Cover Story: Gestational diabetes mellitus (GDM) represents a heterogeneous group of hyperglycemic metabolic disorders that are associated with health outcomes for mothers and offspring. Currently, diagnosis of GDM is based on repetitive measurement of increased fasting plasma glucose (FPG) or upon results showing increased postprandial plasma glucose (PPG). Recently, it was discovered that the changes in the gut microbiome during pregnancy are associated with insulin resistance and obesity. In this study, relevant products of gut bacteria, short-chain fatty acids (SCFA), and their derivatives were evaluated together with baseline body composition characteristics and common biochemical parameters in women with three different phenotypes of GDM, healthy pregnant and nonpregnant women. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (33)

  • Article
  • Open Access
20 Citations
3,240 Views
15 Pages

The identification of microscale oil structures formed from deposited oil droplets on the filter front face of a coalescence filter medium is essential to understand the initial state of the coalescence filtration process. Using µ-CT imaging and a de...

  • Article
  • Open Access
14 Citations
3,658 Views
19 Pages

In the present study, acetaminophen (ACT) molecularly imprinted polymer (ACT-MIP) were successfully synthesized via surface imprinting polymerization. The structural and morphological properties of ACT-MIP were characterized using various analytical...

  • Review
  • Open Access
30 Citations
6,150 Views
16 Pages

Recent Advances on the Development of Chemosensors for the Detection of Mercury Toxicity: A Review

  • Shiva Prasad Kollur,
  • Chandan Shivamallu,
  • Shashanka K. Prasad,
  • Ravindra Veerapur,
  • Sharanagouda S. Patil,
  • Charley A. Cull,
  • Johann F. Coetzee and
  • Raghavendra G. Amachawadi

The harmful impact of mercury on biological systems is of great concern. Regardless of the efforts made by the regulating agencies, a decrease in Hg2+ concentration has not been realized, and hence mercury accumulation in the environment remains of u...

  • Article
  • Open Access
10 Citations
4,462 Views
16 Pages

The determination of alcohol, SO2, and total acids in wine through conventional laboratory techniques have some limitations related to the amount of the samples, analytical preparation of laboratory staff, and time to carry out the analysis. In recen...

  • Article
  • Open Access
8 Citations
3,109 Views
13 Pages

Validation and Clinical Application of a New Liquid Chromatography Coupled to Mass Spectrometry (HPLC-MS) Method for Dalbavancin Quantification in Human Plasma

  • Valeria Avataneo,
  • Miriam Antonucci,
  • Elisa Delia De Vivo,
  • Antonio Briozzo,
  • Jessica Cusato,
  • Francesca Bermond,
  • Corrado Vitale,
  • Francesco Vitale,
  • Alessandra Manca and
  • Antonio D’Avolio
  • + 4 authors

Dalbavancin (DBV) is an intravenous long-acting second-generation glycolipopeptide antibiotic with high efficacy and excellent tolerability, approved for use in the treatment of Gram-positive skin and skin structure infections (ABSSSI). Nevertheless,...

  • Article
  • Open Access
4 Citations
3,162 Views
17 Pages

An assessment was performed on methods of separating and disinfecting airborne droplet nuclei containing viruses, such as SARS-CoV-2. The droplet nuclei originate from evaporating aerosols emitted by the coughing, singing, sneezing, etc. of infected...

  • Article
  • Open Access
10 Citations
3,597 Views
11 Pages

Studies on the Separation and Purification of the Caulis sinomenii Extract Solution Using Microfiltration and Ultrafiltration

  • Xi Wang,
  • Huimin Feng,
  • Halimulati Muhetaer,
  • Zuren Peng,
  • Ping Qiu,
  • Wenlong Li and
  • Zheng Li

The separation and purification process of alkaloids faces great challenges of pollution, high energy consumption and low continuity. In this study, the effects of ceramic microfiltration (MF) membrane (membrane pore size of 0.50 μm, 0.20 μm, 0.05 μm...

  • Article
  • Open Access
6 Citations
4,245 Views
12 Pages

Ellagic acid is a phenolic compound that exhibits both antimutagenic and anticarcinogenic activity in a wide range of assays in vitro and in vivo. It occurs naturally in some foods such as raspberries, strawberries, grapes, and black currants. In thi...

  • Article
  • Open Access
11 Citations
2,738 Views
16 Pages

Role of Extracts Obtained from Rainbow Trout and Sole Side Streams by Accelerated Solvent Extraction and Pulsed Electric Fields on Modulating Bacterial and Anti-Inflammatory Activities

  • Min Wang,
  • Jianjun Zhou,
  • Noelia Pallarés,
  • Christine Bäuerl,
  • Maria Carmen Collado,
  • Basharat Nabi Dar and
  • Francisco J. Barba

In this study, accelerated solvent extraction (ASE) and pulsed electric field (PEF) were used as innovative approaches to recover extracts from rainbow trout and sole side streams rich in high-added-value compounds. Then, after aseptic filtration, th...

  • Article
  • Open Access
5 Citations
4,393 Views
13 Pages

Plasma Short-Chain Fatty Acids and Their Derivatives in Women with Gestational Diabetes Mellitus

  • Eliška Ivanovová,
  • Barbora Piskláková,
  • Jaroslava Friedecká,
  • Ondřej Krystyník,
  • David Friedecký and
  • David Karásek

Gestational diabetes mellitus (GDM) represents a heterogeneous group of hyperglycemic metabolic disorders that are associated with health outcomes for mothers and offspring. Currently, diagnosis of GDM is based on repetitive measurement of increased...

  • Article
  • Open Access
1 Citations
3,927 Views
16 Pages

(1) Background: Ethanol precipitation is widely used in the manufacturing traditional Chinese medicines (TCMs). Insufficient mixing of ethanol solution and concentrate usually results in the coating loss of active ingredients. However, there is no in...

  • Review
  • Open Access
22 Citations
7,814 Views
18 Pages

The bioactive Hemp Seed Oil (HSO) is becoming very popular in the medical and research fields due to its antimicrobial properties against several diseases caused by bacteria and fungi. However, the effect of hemp-growing factors and extraction method...

  • Article
  • Open Access
3 Citations
2,852 Views
14 Pages

The rapid, highly-sensitive and ecologically greener reversed-phase (RP)/normal-phase (NP) high-performance thin-layer chromatography (HPTLC) densitometric technique has been developed and validated for the determination of trans-resveratrol (TRV). T...

  • Article
  • Open Access
5 Citations
4,702 Views
18 Pages

Geochemical Analysis of Two Samples of Bitumen from Jars Discovered on Muhut and Masirah Islands (Oman)

  • Jacques Connan,
  • Michael H. Engel,
  • Robert B. Jackson,
  • Seth Priestman,
  • Tom Vosmer and
  • Alex Zumberge

Two samples of bitumen were obtained, one from a torpedo jar (c. 3rd–8th C. AD) from Masirah island and one from a Tunisian jar (c. 18th C. AD) from Muhut island off the central coast of Oman. Steranes and terpanes, as well as isotope data on chromat...

  • Article
  • Open Access
17 Citations
3,545 Views
10 Pages

The stability of analytes is a critical point in chemical analysis, especially in the field of trace levels residue analysis. Nowadays, due to advances in analytical technology and in separation sciences, the analyses of water have been improved. Unf...

  • Article
  • Open Access
14 Citations
6,294 Views
15 Pages

1,2-Propylene Glycol: A Biomarker of Exposure Specific to e-Cigarette Consumption

  • Therese Burkhardt,
  • Nikola Pluym,
  • Gerhard Scherer and
  • Max Scherer

Over the past decade, new emerging tobacco and nicotine-delivery products have changed the tobacco landscape. Especially, electronic cigarettes (ECs) have been suggested to be considered for tobacco harm reduction, reinforcing the need to identify no...

  • Feature Paper
  • Article
  • Open Access
22 Citations
3,498 Views
15 Pages

Chemical and Antioxidant Characterization of the Portuguese Heather Honey from Calluna vulgaris

  • Luís Rodrigues da Silva,
  • Renan Campos Chisté and
  • Eduarda Fernandes

The Calluna vulgaris honey produced in Portugal, concerning its phenolic compounds and abscisic acids profiles, as well as its antioxidant activity and the protective effect against oxidative damage in human erythrocytes were herein performed for the...

  • Feature Paper
  • Article
  • Open Access
2 Citations
3,248 Views
11 Pages

Selectivity in separation science is defined as the extent to which a method can determine the target analyte free of interference. It is the backbone of any method and can be enhanced at various steps, including sample preparation, separation optimi...

  • Article
  • Open Access
10 Citations
10,376 Views
9 Pages

Nutritional Value of Sea Urchin Roe (Strongylocentrotidae)—Study of Composition and Storage Conditions

  • Victoria A. Matveeva,
  • Lidia V. Shulgina,
  • Yury V. Prikhodko,
  • Yury P. Shulgin,
  • Katarzyna Madej and
  • Wojciech Piekoszewski

Although the roe of sea urchins inhabiting the Far Eastern seas possesses many healing properties and may be used as a dietary product, a reduction and deterioration in its nutritional quality during storage occurs. Therefore, in order to make sea ur...

  • Article
  • Open Access
12 Citations
3,347 Views
13 Pages

Phytochemical Responses to Salt Stress in Red and Green Baby Leaf Lettuce (Lactuca sativa L.) Varieties Grown in a Floating Hydroponic Module

  • Giandomenico Corrado,
  • Paola Vitaglione,
  • Maria Giordano,
  • Giampaolo Raimondi,
  • Francesco Napolitano,
  • Emilio Di Stasio,
  • Ida Di Mola,
  • Mauro Mori and
  • Youssef Rouphael

Lettuce (Lactuca sativa L.) is one of the most popular leafy vegetables, appreciated globally as a low-calorie food with bioactive compounds. The application of a low dose of abiotic stress is considered a sustainable pre-harvest strategy to modify t...

  • Review
  • Open Access
93 Citations
11,379 Views
24 Pages

Deep Eutectic Solvents (DESs) as Green Extraction Media of Beneficial Bioactive Phytochemicals

  • Ali Sami Dheyab,
  • Mohd Fadzelly Abu Bakar,
  • Mohamed AlOmar,
  • Siti Fatimah Sabran,
  • Ahmad Fathi Muhamad Hanafi and
  • Azman Mohamad

Deep eutectic solvents (DES) are a mixture of two or more components and are classified as ionic solvents with special properties such as low volatility, high solubility, low melting points, low-cost materials and are less toxic to humans. Using DES...

  • Article
  • Open Access
17 Citations
12,631 Views
14 Pages

Methylene chloride, commonly known as dichloromethane (DCM), is a widely used chemical for chromatography separation within the polymer, chemical, and pharmaceutical industries. With the ability to effectively solvate heterocyclic compounds, and prop...

  • Article
  • Open Access
14 Citations
4,562 Views
11 Pages

Tyrosol and Hydroxytyrosol Determination in Extra Virgin Olive Oil with Direct Liquid Electron Ionization-Tandem Mass Spectrometry

  • Veronica Termopoli,
  • Maurizio Piergiovanni,
  • Achille Cappiello,
  • Pierangela Palma and
  • Giorgio Famiglini

Extra virgin olive oil (EVOO) is one of the main ingredients of the Mediterranean diet. It is claimed as a functional food for its unique content of health-promoting compounds. Tyrosol (Tyr), Hydroxytyrosol (Htyr), and their phenolic derivatives pres...

  • Article
  • Open Access
16 Citations
4,693 Views
15 Pages

Benzo[a]pyrene (BaP), a human carcinogen, is formed during the incomplete combustion of organic matter such as tobacco. A suitable biomarker of exposure is the monohydroxylated metabolite 3-hydroxybenzo[a]pyrene (3-OH-BaP). We developed a sensitive L...

  • Article
  • Open Access
5 Citations
3,434 Views
11 Pages

Reverse electrodialysis is a promising membrane technology to generate energy from controlled mixing of water streams of different salinities. Electrical potentials generate on the ion exchange membranes (IEMs) when selective transport of cations and...

  • Article
  • Open Access
8 Citations
5,244 Views
11 Pages

Rolling Circle and Loop Mediated Isothermal Amplification Strategy for Ultrasensitive miRNA Detection

  • Zheng Cao,
  • Xianfeng Jiang,
  • Guizhou Xiao,
  • Mingcheng Xu,
  • Hui Liu and
  • Sheng Cai

Rolling circle amplification (RCA) and loop mediated isothermal amplification (LAMP) were combined to establish the rolling circle and loop mediated isothermal amplification (RC-LAMP) method for miRNA detection. With the participation of Bst 2.0 DNA...

  • Article
  • Open Access
10 Citations
5,650 Views
12 Pages

The most important process in immortelle is the extraction of the essential oil by distillation. The chemical properties of the plant depend largely on the cultivation type, climatic conditions and agrotechnical measures. In this work, studies were c...

  • Article
  • Open Access
30 Citations
7,886 Views
17 Pages

Targeted Characterization of the Chemical Composition of JUUL Systems Aerosol and Comparison with 3R4F Reference Cigarettes and IQOS Heat Sticks

  • Xin Chen,
  • Patrick C. Bailey,
  • Clarissa Yang,
  • Bryant Hiraki,
  • Michael J. Oldham and
  • I. Gene Gillman

Aerosol constituent yields have been reported from a wide range of electronic nicotine delivery systems. No comprehensive study has been published on the aerosol constituents generated from the JUUL system. Targeted analyses of 53 aerosol constituent...

  • Article
  • Open Access
3 Citations
2,697 Views
12 Pages

Agricultural products are indispensable for equilibrated diets since they discharge minerals and several bioactive constituents. Considering the increasing demand for organic products, research has been conducted over recent years to investigate whet...

  • Article
  • Open Access
5 Citations
6,144 Views
11 Pages

30 September 2021

Cyanoacetamides are vital synthons in synthetic organic chemistry. However, methods to enantiopure cyanoacetamides have not yet been well explored. In this work, the preparation of cyanoacetamide synthons RS-(1a4a) or methoxyacetamides RS-(1b4b) in...

  • Article
  • Open Access
1 Citations
2,977 Views
18 Pages

Determination and Chemometrics-Assisted Comparative Analysis of Active Components in Different Tissue of Rana chensinensis

  • Jianqiu Zhang,
  • Zhongyao Wang,
  • Shihan Wang,
  • Changli Zhang,
  • Nan Li,
  • Dongliang Xu,
  • Yong Yang and
  • Yongsheng Wang

28 September 2021

In this study, the chemical composition of different tissues of Rana temporaria chensinensis David derived from the same individual was analyzed by comparative approach. First, pre-column derivatization combined with high performance liquid chromatog...

  • Feature Paper
  • Article
  • Open Access
7 Citations
6,764 Views
13 Pages

27 September 2021

A reversed-phase high-pressure liquid chromatography (RP-HPLC) method was developed and subsequently validated for the simultaneous determination of butamirate citrate (BC) and benzoic acid (BA) in cough syrup. The separation was performed employing...

  • Article
  • Open Access
9 Citations
4,644 Views
7 Pages

Determination of Genotoxic Azide Impurity in Cilostazol API by Ion Chromatography with Matrix Elimination

  • Boglárka Páll,
  • Zsuzsa Gyenge,
  • Róbert Kormány and
  • Krisztián Horváth

23 September 2021

Cilostazol is a commonly used active pharmaceutical ingredient (API) to treat and reduce the symptoms of intermittent claudication in peripheral vascular disease. Recently, it was found to be a potential medicine in the effective treatment of COVID-1...

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Separations - ISSN 2297-8739