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Separations, Volume 12, Issue 3

2025 March - 18 articles

Cover Story: Several D-amino acid residue-containing peptides (DAACPs) exhibit biological activities. Among these, the D-amino acid-containing tripeptide L-Asn-D-Trp-L-Phe-NH2 from Aplysia kurodai affects invertebrate cardiac activity. The chirality of its tryptophan residue influences its structure and function. We achieved the chiral separation of the tripeptide and its diastereomer using (S)-3,3′-diphenyl-1,1′-binaphthyl-20-crown-6-ether columns (CR-I(+)), aided by lowering the acetonitrile and methanol ratio in the mobile phase. Molecular dynamics simulations presented an interaction view of the tripeptide and the chiral selector. These results highlight the stereoselective recognition of DAACPs by CR-I columns. View this paper
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Articles (18)

  • Article
  • Open Access
69 Citations
11,269 Views
50 Pages

The rapid pace of global industrialization and population growth has intensified freshwater scarcity and water pollution, necessitating urgent solutions. Adsorption technology, favored for its cost-effectiveness, simplicity, and scalability, has emer...

(This article belongs to the Special Issue Design and Preparation of Sustainable Separation Membrane for Efficient Water Purification)
  • Review
  • Open Access
15 Citations
7,274 Views
68 Pages

The efficient separation and removal of carbon dioxide (CO2) from its mixtures is an important technological challenge to limit effects resulting from the increase of the carbon dioxide concentration in the atmosphere. Membrane technology is an envir...

(This article belongs to the Section Materials in Separation Science)
  • Review
  • Open Access
66 Citations
7,343 Views
17 Pages

The rapid expansion of industrial and agricultural activities in recent years has significantly contributed to water pollution leading to a decline in water quality and the need for effective treatment and reuse strategies. Metal contamination in wat...

(This article belongs to the Special Issue Materials from Biomass and Waste for Adsorption Applications)
  • Article
  • Open Access
3 Citations
1,716 Views
19 Pages

With the rapid development of China’s zinc-related industries, the grade of zinc concentrate has steadily declined, while the generation of zinc-containing solid waste has shown a significant upward trend. To address this issue, a collaborative...

  • Article
  • Open Access
16 Citations
4,303 Views
12 Pages

Assessment of Bioactive Compounds and Antioxidant Activity of Barley Sprouts

  • Geon Oh,
  • Im-Joung La,
  • Do-Sang Lee,
  • Jong-Woo Chae and ,
  • Ji-Hyun Im,
  • Seon Woo Park,
  • Xiaolu Fu,
  • June-Seok Lim,
  • Min-Hye Kim and
  • Ok-Hwan Lee
  • + 7 authors+ 2 authors

Barley sprouts, rich in bioactive compounds, have gained attention as functional food ingredients because of their antioxidant potential. This study evaluated their bioactive composition and antioxidant capacity, focusing on the saponarin, chlorophyl...

  • Article
  • Open Access
3,132 Views
8 Pages

Several D-amino acid residue-containing peptides (DAACPs) with antimicrobial, cardio-excitatory, and neuronal activities have been identified in various species. The L-Asn-D-Trp-L-Phe-NH2 (N(dW)F) tripeptide, derived from Aplysia kurodai, exhibits ca...

(This article belongs to the Special Issue Peptide Synthesis, Separation and Purification)
  • Article
  • Open Access
1 Citations
1,737 Views
14 Pages

In this study, Acidthiobacillus ferrooxidans LX5 was used as an experimental microbial strain, and differences in biological oxidation between high-sulfur coal and pure pyrite were thoroughly investigated over 18 days in acidic environments with init...

(This article belongs to the Section Materials in Separation Science)
  • Review
  • Open Access
62 Citations
17,336 Views
40 Pages

Greener Pectin Extraction Techniques: Applications and Challenges

  • Shaikh Manirul Haque,
  • Abuzar Kabir,
  • Elaref Ratemi,
  • Mohamed Elzagheid and ,
  • Sreekumar Parambathmadhom Appu,
  • Syed Sauban Ghani and
  • Abdullah Sarief
  • + 2 authors+ 0 author

Pectin is a complex and versatile polysaccharide crucial for various industries. It functions as a thickener, gelling agent, emulsifier, and low-calorie food. Its anti-inflammatory and immunomodulatory properties have attracted biomedical interest, w...

  • Review
  • Open Access
5 Citations
2,371 Views
12 Pages

Although total selenium content is still useful in many areas, knowledge of its speciation is gaining importance as its various chemical forms have different environmental effects, toxicities and biological utilization. Among several methods used for...

(This article belongs to the Section Materials in Separation Science)
  • Article
  • Open Access
9 Citations
3,578 Views
11 Pages

Green Protein Extraction from Hazelnut Press Cake: Yield, Efficiency, and Secondary Structure Analysis

  • Bruna Anzà,
  • Silvia Fraterrigo Garofalo,
  • Alessandro Lapolla and
  • Debora Fino

Hazelnut (Corylus avellana L.) oil production generates press cakes, a by-product rich in plant-based proteins. As demand for alternative proteins grows, sustainable extraction methods like deep eutectic solvents (DESs) are essential for reducing the...

(This article belongs to the Special Issue Novel Solvents and Methods for Extraction of Chemicals)
  • Article
  • Open Access
1 Citations
1,696 Views
16 Pages

Enrichment of Trace Selenium in Water Based on Metal−Organic Framework Materials and Reversed−Phase Ultra−High−Performance Liquid Chromatography−Diode Array Determination

  • Hanqing Cai,
  • Hongmei Guo,
  • Hanlu Jing,
  • Pingping Wen and ,
  • Qiuying Wu,
  • Yang Li,
  • Zhirong Suo and
  • Jian Zhang
  • + 3 authors+ 0 author

A method for the determination of trace selenium in water enriched by metal–organic−framework material (MIL−125−NH2) and reversed−phase ultra−high−performance liquid chromatography−diode array detection...

  • Article
  • Open Access
5 Citations
2,146 Views
13 Pages

The Bio-Desulfurization of Cassiterite–Polymetallic Sulfide Ores Enhanced by a Consortium of Moderately Thermophilic Bacteria

  • Mingwei Wang,
  • Weimin Zeng,
  • Zhen Yan,
  • Li Shen and ,
  • Runlan Yu,
  • Xueling Wu,
  • Jiaokun Li,
  • Guanzhou Qiu,
  • Wolfgang Streit and
  • Yuandong Liu
  • + 5 authors+ 0 author

Sulfides should be removed before the recovery of cassiterite from tin-rich minerals due to their similarity in flotation properties. However, the traditional methods used have low selectivity. Therefore, moderately thermophilic microorganisms were u...

(This article belongs to the Section Purification Technology)
  • Article
  • Open Access
2,609 Views
13 Pages

Multiple cyclones working in series are sufficient for heavy separation tasks at the cost of significant energy consumption. The majority of researchers conducting optimization studies on multiple cyclones have attempted to find the best possible com...

  • Article
  • Open Access
6 Citations
1,939 Views
16 Pages

A robust and elegant approach, based on the Two-Zone Moment Analysis (TZMA) method, is proposed to assess the contributions of the mobile and stationary zones, HCm and HCs, to the C term HC in the van Deemter equation for plate height. The TZMA metho...

(This article belongs to the Section Chromatographic Separations)
  • Article
  • Open Access
5 Citations
3,486 Views
17 Pages

In the present work, brewer’s spent grain, BSG, the main by-product of beer production, was applied for the recovery of total polyphenols (TPs). Whole and ground BSG (wBSG and gBSG), derived from a Pilsen beer, was subjected to a solvent extrac...

(This article belongs to the Special Issue Novel Solvents and Methods for Extraction of Chemicals)
  • Article
  • Open Access
1 Citations
1,958 Views
12 Pages

Isolation, Spectral Assignments and Absolute Configuration of a Linear Hexapeptide from the Culture Broth of the Plant-Associated Actinomycete Actinomycetospora sp. CA-287887

  • Katerina Georgousaki,
  • Nikolaos Tsafantakis,
  • Ignacio González,
  • Jesús Martin and ,
  • Thomas Andrew Mackenzie,
  • Sentiljana Gumeni,
  • Ioannis P. Trougakos,
  • Fernando Reyes,
  • Olga Genilloud and
  • Nikolas Fokialakis
  • + 5 authors+ 0 author

A high proteolytic-resistant hexapeptide (αs1-CN 181–186) (1) along with two known 2,5-diketopiperazines, namely cyclo-(L-Pro-L-Phe) (2) and cyclo-(L-Pro-L-Tyr) (3), as well as the carboxylic acid 2-hydroxyphenylacetic acid (4), were isol...

(This article belongs to the Section Analysis of Natural Products and Pharmaceuticals)
  • Article
  • Open Access
6 Citations
1,587 Views
15 Pages

Effect of Vacuum Process on Enrichment of Low-Concentration Coal Mine Methane by Adsorption

  • Yuanyuan Kang,
  • Yingshu Liu,
  • Wenhai Liu,
  • Ye Li and ,
  • Ningqi Sun,
  • Quanli Zhang,
  • Ziyi Li and
  • Xiong Yang
  • + 3 authors+ 0 author

The massive emission of low-concentration coal mine methane (CMM) has resulted in the ineffective utilization of a large amount of energy methane and caused environmental pollution. The gas mixture used in the study consisted of methane (CH4) 12% and...

(This article belongs to the Section Separation Engineering)
  • Article
  • Open Access
3 Citations
2,886 Views
11 Pages

Isolation and Hydrolysis of Proteins from Vigna umbellata and the Effect on Their Antioxidant and Anticancer Activities

  • Leopoldo González-Cruz,
  • Leonardo Morales-Cerda,
  • Gerardo Teniente-Martínez,
  • Carmen Valadez-Vega and
  • Aurea Bernardino-Nicanor

Rice bean is a legume that is considered to be an important source of protein; it is still poorly understood but can produce peptides with various biological activities. These peptides can be released by enzymes during gastrointestinal passage and ha...

(This article belongs to the Special Issue Extraction and Analysis of Chemical Composition from Natural Products and Metabolites)
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Separations - ISSN 2297-8739