Skip to Content
You are currently on the new version of our website. Access the old version .

Separations, Volume 11, Issue 1

2024 January - 36 articles

Cover Story: Extracting and profiling volatile metabolites from biological sample matrices reveals disease signatures, which is increasingly recognized as a frontier in disease diagnosis. Headspace solid-phase microextraction (HS-SPME) has been widely used to extract volatile compounds from biological samples, but its efficiency varies with different sample matrices. In this study, several HS-SPME parameters were optimized for lung lavage analysis. The new method produced a 340% increase in the total peak area and an 80% increase in peak number across various chemical classes. Our research demonstrates a significant enhancement in extraction performance and provides insights into how different compounds, affected by the matrix ionic strength, depend on their polarity. Overall, this optimization work paves the way for more precise and comprehensive volatile compound discovery using HS-SPME. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (36)

  • Article
  • Open Access
12 Citations
8,320 Views
16 Pages

Gallic acid, known for its biological activity contributing to human health, including antioxidant, anti-inflammatory, anticancer, and antimutagenic properties, was the focus of this study. The solubility of gallic acid was experimentally measured in...

  • Review
  • Open Access
33 Citations
10,205 Views
26 Pages

Potential of Deep Eutectic Solvents in the Extraction of Organic Compounds from Food Industry By-Products and Agro-Industrial Waste

  • Maja Molnar,
  • Dajana Gašo-Sokač,
  • Mario Komar,
  • Martina Jakovljević Kovač and
  • Valentina Bušić

Global food waste has a huge impact on the environment, as it is a source of greenhouse gas emissions and wasted natural resources. Across the world, over 30% of food is lost or wasted each year. Aside from this, the food industry, as well, is one of...

  • Article
  • Open Access
2 Citations
3,853 Views
12 Pages

HPLC-MS/MS Analysis for Sphingosine 1-Phosphate after the Dephosphorylation by Hydrogen Fluoride

  • Hee-Jung Kim,
  • Seo-Hyeon Jung,
  • Shokhid Gulyamov,
  • Hyun-Gy Lee,
  • Oybek Boyjigitov and
  • Yong-Moon Lee

Sphingosine 1-phosphate (S1P) is a signaling lipid molecule involved in various cellular processes. It is important to develop a quantitative method for S1P to determine endogenous levels and to investigate its functions. As S1P is a tiny lipid compo...

  • Article
  • Open Access
4 Citations
3,075 Views
19 Pages

Theoretical Calculations and Experimental Investigation of Separation of Dy3+, Er3+, Tm3+ and Yb3+ by Cascade Extraction in TOGDA–Kerosene/Hydrochloric Acid System

  • Yuzhen Bai,
  • Aijun Gong,
  • Lina Qiu,
  • Yiwen Wang,
  • Ge Gao,
  • Weiyu Zhao,
  • Yang Liu,
  • Jiayi Yin,
  • Xinyu Huang and
  • Yiyang Chen

The hot spot extraction agent N,N,N′,N′-tetraoctyl-3-oxoglutaramide (TODGA) has the advantages of novelty, high efficiency and environmental protection in the separation of rare earths by tandem extraction. In this paper, the characterist...

  • Article
  • Open Access
5 Citations
3,598 Views
13 Pages

HPLC/DAD Analysis and Antioxidant Activity of Adlay Sprouts and Seeds

  • Gia-Han Tran,
  • Neil-Patrick Uy,
  • Shi-Heon Kang,
  • Wonseok Heo,
  • Eun-Song Lee,
  • Seong-Soo Roh and
  • Sanghyun Lee

Adlay is an annual plant known for its abundant bioactive compounds and diverse pharmacological activities. Coixol, a key component found in various parts of adlay, significantly contributes to its biological activity. This study was conducted to ext...

  • Article
  • Open Access
2 Citations
3,230 Views
13 Pages

Puerariae Radix is one of the most widely used ancient traditional Chinese medicines and is also consumed as food, which has rich edible and medicinal value. Puerariae Radix can be divided into Puerariae Lobatae Radix (PL) and Puerariae Thomsonii Rad...

  • Review
  • Open Access
5 Citations
4,800 Views
22 Pages

Sunscreens are topical preparations containing one or more compounds that protect humans from ultraviolet (UV) light. This review focuses on analytical methods, particularly liquid chromatography, with the aim of identifying and determining UV filter...

  • Article
  • Open Access
2 Citations
2,359 Views
17 Pages

Preparation and Application of Si@Al Adsorbents for Different Pollutants Removal from Aqueous Solution

  • Xiaoyu Xu,
  • Jiahua Liu,
  • Yuang Cao,
  • Han Wang,
  • Keqiang Zhang,
  • Chein-Chi Chang and
  • Suli Zhi

This study tried to use electroflocculating precipitated waste to prepare a Si@Al adsorbent by simply mixing sodium silicate at a mass ratio of 4:1 and calcining at 200 °C for 2 h. The adsorbent was low cost, high efficiency, and could remove a v...

  • Article
  • Open Access
3 Citations
5,603 Views
11 Pages

The Dewatering Performance of a Compact Screw Press Manure Separator for Non-Typical Substrates

  • Thomas Senfter,
  • Igor Schweiggl,
  • Manuel Berger,
  • Christian Mayerl,
  • Tobias Kofler,
  • Michael Kraxner,
  • Axel Steffens and
  • Martin Pillei

The dewatering of substrates is one of the key tasks in the handling of material flows in a circular economy. Besides belt filters, sedimenters, and decanters, screw presses are frequently used to reduce the water content of substrates. However, scre...

  • Article
  • Open Access
1 Citations
7,129 Views
15 Pages

Headspace solid-phase micro-extraction (HS-SPME) is a prevalent technique in metabolomics and volatolomics research. However, the performance of HS-SPME can vary considerably depending on the sample matrix. As a result, fine-tuning the parameters for...

  • Review
  • Open Access
8 Citations
4,289 Views
16 Pages

Because of the requirements for accelerating the construction of a green, low-carbon, and recycling economy development system, the petrochemical industry has been paying attention to green and low-carbon transformations and innovations. Oily sludge...

  • Article
  • Open Access
7 Citations
4,049 Views
16 Pages

Tuning Nanopores in Tubular Ceramic Nanofiltration Membranes with Atmospheric-Pressure Atomic Layer Deposition: Prospects for Pressure-Based In-Line Monitoring of Pore Narrowing

  • Michiel Nijboer,
  • Asif Jan,
  • Mingliang Chen,
  • Kevin Batenburg,
  • Julia Peper,
  • Tom Aarnink,
  • Fred Roozeboom,
  • Alexey Kovalgin,
  • Arian Nijmeijer and
  • Mieke Luiten-Olieman

Atomic layer deposition (ALD) is known for its unparalleled control over layer thickness and 3D conformality and could be the future technique of choice to tailor the pore size of ceramic nanofiltration membranes. However, a major challenge in tuning...

  • Article
  • Open Access
4 Citations
4,328 Views
11 Pages

Phthalates are the synthetic chemical plasticizers with the most varied uses and are a source of concern due to their toxicity and ubiquity, so much so that even plasticizer-free polymers can contain them as non-intentionally added substances (NIAS)....

  • Article
  • Open Access
6 Citations
5,216 Views
16 Pages

Characterization, Antioxidant and Cytotoxic Evaluation of Demethoxycurcumin and Bisdemethoxycurcumin from Curcuma longa Cultivated in Costa Rica

  • Andrea Mariela Araya-Sibaja,
  • Felipe Vargas-Huertas,
  • Silvia Quesada,
  • Gabriela Azofeifa,
  • José Roberto Vega-Baudrit and
  • Mirtha Navarro-Hoyos

The biological activities of curcuminoids, the main polyphenol constituents of Curcuma longa (turmeric), have been the subject of many studies in recent years. However, these studies have focused on the major active compound, curcumin (CUR), while ot...

  • Article
  • Open Access
2 Citations
2,275 Views
11 Pages

We investigate band broadening in the most widely adopted configuration of micro-pillar array columns (μPACs)—specifically, a cylindrical pillar array where both the pillar walls and the channel bottom are coated with a thin layer of mesopor...

  • Editorial
  • Open Access
2,475 Views
14 Pages

The origin of the International Symposia on Separation Sciences (ISSS) can be found in the national gas chromatography scientific meetings held in Zagreb, Croatia, from 1967 and later at Plitvice Lakes until 1988 [...]

  • Article
  • Open Access
3 Citations
2,602 Views
13 Pages

The accumulation of uncollected fly ash from flue gas in post-combustion CO2 capture processes is a significant concern in current coal-fired power plants due to its potential impact on the performance of CO2 absorbent and absorption towers. In order...

  • Article
  • Open Access
5 Citations
2,453 Views
13 Pages

Effective Utilization of Sulfur Wastewater by Photocatalytic System Using B/CuO/ZnO

  • Ikki Tateishi,
  • Mai Furukawa,
  • Hideyuki Katsumata and
  • Satoshi Kaneco

B-doped zinc oxide/copper oxide composites prepared using a simple method showed high photocatalytic hydrogen production activity in the presence of aqueous sulfide solutions. Co-modification of the CuO composite with B-doping caused an increase in t...

  • Article
  • Open Access
2,713 Views
12 Pages

In this work, three cyanoalkyl silicone GC stationary-phase polymers, namely OV-105, OV-225, and OV-275, were investigated as potential extractants for dispersive liquid–liquid microextraction (DLLME). The OV-225 polymer (cyanopropylmethyl-phen...

  • Article
  • Open Access
12 Citations
4,468 Views
19 Pages

This study investigated the adsorption performance of hydrothermal carbon derived from banana peel and modified with different concentrations of phosphoric acid solution, then used to adsorb lead ions in an aqueous solution. The surface structure and...

  • Article
  • Open Access
5 Citations
2,526 Views
17 Pages

Prediction of Bleeding via Simulation of Hydrodynamics in Centrifugal Partition Chromatography

  • Felix Buthmann,
  • Sophia Volpert,
  • Jörg Koop and
  • Gerhard Schembecker

Centrifugal Partition Chromatography (CPC) utilizes a two-phase liquid–liquid system as mobile and stationary phases. During operation, the latter continuously drains out of the rotor, despite it being in fact stationary, leading to decreasing...

  • Article
  • Open Access
2,697 Views
10 Pages

Isolation and Chemotaxonomic Implications of Tenelloside, a Novel Unusual C-Glycosyl Flavanone from Phyllanthus tenellus Roxb. in Tenerife Island

  • Antonio Francioso,
  • Ignacio Antonio Jiménez Díaz,
  • Carolina Pérez Reyes,
  • Cristina González Montelongo,
  • Marco Pierini,
  • Claudio Villani and
  • Isabel López Bazzocchi

Phyllanthus is a large genus of the Euphorbiaceae family, which has been widely used in traditional medicine. The current study reports the isolation of an unusual C-glycosyl flavonoid, named tenelloside, from Phyllanthus tenellus Roxb., a non-endemi...

  • Article
  • Open Access
1 Citations
2,228 Views
12 Pages

The aim of this work was to investigate the composition of essential oils isolated from fruits of Peucedanum longifolium, and Rhizomatophora aegopodioides (a species which was previously placed in the genus Peucedanum), as well as to compare the obta...

  • Article
  • Open Access
11 Citations
3,388 Views
15 Pages

Optimization of the Extraction of Bioactive Compounds from Cabernet Sauvignon Grape Pomace from Querétaro, Mexico, Using MSPD

  • Tellez-Robles Daniela,
  • López-Cortez Ma. del Socorro,
  • Santoyo-Tepole Fortunata,
  • Rosales-Martínez Patricia,
  • García-Ochoa Felipe,
  • Hernández-Botello Mayuric Teresa and
  • Salgdo-Cruz María de la Paz

Red wine contains polyphenols which are extracted during the winemaking process. However, winemaking is not an extraction; therefore, the resulting byproducts still have a substantial polyphenol content. The aim of this study was to compare two metho...

  • Article
  • Open Access
1 Citations
2,683 Views
18 Pages

Application of the Biomass of Leaves of Diospyros kaki L.f. (Ebenaceae) in the Removal of Metal Ions from Aqueous Media

  • Rodrigo Martorelli Galera,
  • Adrielli Cristina Peres da Silva,
  • Alexandre de Oliveira Jorgetto,
  • Marcos Henrique Pereira Wondracek,
  • Margarida Juri Saeki,
  • José Fabián Schneider,
  • Valber de Albuquerque Pedrosa,
  • Marco Autônio Utrera Martines and
  • Gustavo Rocha Castro

Using straightforward and cost-effective methods, persimmon leaves were converted into high-quality powder. This powder was applied as an adsorbent for the removal of Cu(II) and Cd(II) from aqueous solutions. Scanning electron microscopy (SEM) reveal...

  • Review
  • Open Access
2 Citations
5,340 Views
22 Pages

Sulfolane, a highly water-soluble industrial solvent, has raised environmental concerns due to its widespread usage and its prolonged persistence once released into the environment. To assess the extent of contamination effectively, reliable analytic...

  • Article
  • Open Access
3 Citations
3,361 Views
19 Pages

A novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the simultaneous determination of tipiracil (TIP), trifluridine (FTD), and their metabolites, 5-trifluoromethyluracil (FTY) and 5-carboxy-2&...

  • Article
  • Open Access
3 Citations
2,881 Views
15 Pages

Immobilisation of Molybdenum in a Sulphate-Reducing Bioreactor

  • Pavlina Kousi,
  • Dimitra-Artemis Strongyli,
  • Petros E. Tsakiridis,
  • Artin Hatzikioseyian and
  • Emmanouella Remoundaki

This work presents a biological remediation process for molybdenum-bearing wastewater which may lead to the fabrication of biogenic Mo chalcogenide particles with (photo)catalytic properties. The process is based on dissimilatory sulphate reduction,...

  • Article
  • Open Access
3,703 Views
14 Pages

Straw is an important by-product of crop production. It has been widely used as a feed as well as in fruit–vegetable production due to exerting a positive impact on soil and crop health and quality in the operated areas. On the other hand, appl...

  • Article
  • Open Access
6 Citations
3,476 Views
15 Pages

Recovery of Valuable Metals from Polymetallic Refractory Concentrate by a Sulfuric Acid Curing and Leaching Method

  • Wei Jiang,
  • Jilai Xue,
  • Kaixi Jiang,
  • Xunxiong Jiang,
  • Shengdong Wang,
  • Jinping Hu,
  • Derek O. Northwood,
  • Kristian E. Waters and
  • Hao Ma

Sulfuric acid curing and leaching is a promising technology for treating refractory ores. In this work, a refractory concentrate containing 3191 ppm uranium (U), 2135 ppm niobium (Nb), and 0.7% rare earth minerals (REMs) went through two stages: curi...

  • Article
  • Open Access
2 Citations
2,743 Views
17 Pages

This is the first study aiming to enrich momilactones A (MA) and B (MB) and phenolic compounds in germinated brown rice (GBR) and non-GBR var. Koshihikari and Milky Queen through the cooking process. Extraction methods for these compounds were optimi...

  • Article
  • Open Access
2,133 Views
14 Pages

In recent decades, the versatility of fossil-based polymers has led them to become one of the most used materials for the production of several consumer goods. The destiny of post-consumer plastics is crucial for environmental sustainability. Two are...

  • Article
  • Open Access
3 Citations
2,456 Views
13 Pages

Myrica rubra (Lour.) Siebold & Zucc bark is a traditional natural medicine used by the people of the Dong minority in western Hunan in China. In this study, the main compounds in Myrica rubra bark including epigallocatechin gallate, myricetrin, m...

  • Article
  • Open Access
3 Citations
3,207 Views
15 Pages

Structure Elucidation and Immunoactivity Study of Armillaria mellea Fruiting Body Polysaccharides

  • Qingqing Li,
  • Ying Li,
  • Huazhou Niu,
  • Enhui Wang,
  • Lili Jiao,
  • Hui Li and
  • Wei Wu

Polysaccharides are the main nutritional constituents in the Armillaria mellea fruiting bodies. The structure and immunoactivity of Armillaria mellea polysaccharide are valuable to be determined for development. In the present study, two polysacchari...

  • Article
  • Open Access
31 Citations
10,876 Views
17 Pages

Monosaccharide composition analysis is essential to the structural characterization and research into the biological activity of polysaccharides. In this study, a systematic comparison was performed among commonly used monosaccharide composition anal...

  • Review
  • Open Access
6 Citations
4,523 Views
23 Pages

Since CO2 is an important component of gas emissions, its removal from gas streams is of the utmost importance to fulfill various environmental requirements. The technologies used to accomplish this removal are based mainly on absorption, as well as...

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Separations - ISSN 2297-8739