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Separations, Volume 11, Issue 1

January 2024 - 36 articles

Cover Story: Extracting and profiling volatile metabolites from biological sample matrices reveals disease signatures, which is increasingly recognized as a frontier in disease diagnosis. Headspace solid-phase microextraction (HS-SPME) has been widely used to extract volatile compounds from biological samples, but its efficiency varies with different sample matrices. In this study, several HS-SPME parameters were optimized for lung lavage analysis. The new method produced a 340% increase in the total peak area and an 80% increase in peak number across various chemical classes. Our research demonstrates a significant enhancement in extraction performance and provides insights into how different compounds, affected by the matrix ionic strength, depend on their polarity. Overall, this optimization work paves the way for more precise and comprehensive volatile compound discovery using HS-SPME. View this paper
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Articles (36)

  • Article
  • Open Access
9 Citations
7,275 Views
16 Pages

Gallic acid, known for its biological activity contributing to human health, including antioxidant, anti-inflammatory, anticancer, and antimutagenic properties, was the focus of this study. The solubility of gallic acid was experimentally measured in...

  • Review
  • Open Access
24 Citations
8,818 Views
26 Pages

Potential of Deep Eutectic Solvents in the Extraction of Organic Compounds from Food Industry By-Products and Agro-Industrial Waste

  • Maja Molnar,
  • Dajana Gašo-Sokač,
  • Mario Komar,
  • Martina Jakovljević Kovač and
  • Valentina Bušić

Global food waste has a huge impact on the environment, as it is a source of greenhouse gas emissions and wasted natural resources. Across the world, over 30% of food is lost or wasted each year. Aside from this, the food industry, as well, is one of...

  • Article
  • Open Access
1 Citations
3,181 Views
12 Pages

HPLC-MS/MS Analysis for Sphingosine 1-Phosphate after the Dephosphorylation by Hydrogen Fluoride

  • Hee-Jung Kim,
  • Seo-Hyeon Jung,
  • Shokhid Gulyamov,
  • Hyun-Gy Lee,
  • Oybek Boyjigitov and
  • Yong-Moon Lee

Sphingosine 1-phosphate (S1P) is a signaling lipid molecule involved in various cellular processes. It is important to develop a quantitative method for S1P to determine endogenous levels and to investigate its functions. As S1P is a tiny lipid compo...

  • Article
  • Open Access
3 Citations
2,820 Views
19 Pages

Theoretical Calculations and Experimental Investigation of Separation of Dy3+, Er3+, Tm3+ and Yb3+ by Cascade Extraction in TOGDA–Kerosene/Hydrochloric Acid System

  • Yuzhen Bai,
  • Aijun Gong,
  • Lina Qiu,
  • Yiwen Wang,
  • Ge Gao,
  • Weiyu Zhao,
  • Yang Liu,
  • Jiayi Yin,
  • Xinyu Huang and
  • Yiyang Chen

The hot spot extraction agent N,N,N′,N′-tetraoctyl-3-oxoglutaramide (TODGA) has the advantages of novelty, high efficiency and environmental protection in the separation of rare earths by tandem extraction. In this paper, the characterist...

  • Article
  • Open Access
5 Citations
3,140 Views
13 Pages

HPLC/DAD Analysis and Antioxidant Activity of Adlay Sprouts and Seeds

  • Gia-Han Tran,
  • Neil-Patrick Uy,
  • Shi-Heon Kang,
  • Wonseok Heo,
  • Eun-Song Lee,
  • Seong-Soo Roh and
  • Sanghyun Lee

Adlay is an annual plant known for its abundant bioactive compounds and diverse pharmacological activities. Coixol, a key component found in various parts of adlay, significantly contributes to its biological activity. This study was conducted to ext...

  • Article
  • Open Access
2 Citations
2,820 Views
13 Pages

Puerariae Radix is one of the most widely used ancient traditional Chinese medicines and is also consumed as food, which has rich edible and medicinal value. Puerariae Radix can be divided into Puerariae Lobatae Radix (PL) and Puerariae Thomsonii Rad...

  • Review
  • Open Access
4 Citations
4,117 Views
22 Pages

Sunscreens are topical preparations containing one or more compounds that protect humans from ultraviolet (UV) light. This review focuses on analytical methods, particularly liquid chromatography, with the aim of identifying and determining UV filter...

  • Article
  • Open Access
1 Citations
2,219 Views
17 Pages

Preparation and Application of Si@Al Adsorbents for Different Pollutants Removal from Aqueous Solution

  • Xiaoyu Xu,
  • Jiahua Liu,
  • Yuang Cao,
  • Han Wang,
  • Keqiang Zhang,
  • Chein-Chi Chang and
  • Suli Zhi

This study tried to use electroflocculating precipitated waste to prepare a Si@Al adsorbent by simply mixing sodium silicate at a mass ratio of 4:1 and calcining at 200 °C for 2 h. The adsorbent was low cost, high efficiency, and could remove a v...

  • Article
  • Open Access
2 Citations
4,701 Views
11 Pages

The Dewatering Performance of a Compact Screw Press Manure Separator for Non-Typical Substrates

  • Thomas Senfter,
  • Igor Schweiggl,
  • Manuel Berger,
  • Christian Mayerl,
  • Tobias Kofler,
  • Michael Kraxner,
  • Axel Steffens and
  • Martin Pillei

The dewatering of substrates is one of the key tasks in the handling of material flows in a circular economy. Besides belt filters, sedimenters, and decanters, screw presses are frequently used to reduce the water content of substrates. However, scre...

  • Article
  • Open Access
1 Citations
5,723 Views
15 Pages

Headspace solid-phase micro-extraction (HS-SPME) is a prevalent technique in metabolomics and volatolomics research. However, the performance of HS-SPME can vary considerably depending on the sample matrix. As a result, fine-tuning the parameters for...

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Separations - ISSN 2297-8739Creative Common CC BY license