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Processes, Volume 3, Issue 1

2015 March - 14 articles

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Articles (14)

  • Article
  • Open Access
15 Citations
8,955 Views
18 Pages

20 March 2015

Fibrous materials are prominent among novel chromatographic supports for the separation and purification of biomolecules. In this work, strong anion exchange, quaternary ammonium (Q) functional fibrous adsorbents were evaluated with regards to their...

  • Article
  • Open Access
8 Citations
9,445 Views
26 Pages

16 March 2015

In this study, we present a novel modeling approach which combines ordinary differential equation (ODE) modeling with logical rules to simulate an archetype biochemical network, the human coagulation cascade. The model consisted of five differential...

  • Article
  • Open Access
5 Citations
6,883 Views
17 Pages

11 March 2015

A system is differentially flat if it is Lie–Bäcklund (L-B) equivalent to a free dynamical system that has dimensions equal to that of the input of the original system. Utilizing this equivalence, the problem of nonlinear model predictive control of...

  • Article
  • Open Access
13 Citations
7,738 Views
23 Pages

3 March 2015

Cell-free systems offer many advantages for the study, manipulation and modeling of metabolism compared to in vivo processes. Many of the challenges confronting genome-scale kinetic modeling can potentially be overcome in a cell-free system. For exam...

  • Review
  • Open Access
5 Citations
5,713 Views
25 Pages

17 February 2015

Performance assessment and retuning techniques for proportional-integral-derivative (PID) controllers are reviewed in this paper. In particular, we focus on techniques that consider deterministic performance and that use routine operating data (that...

  • Article
  • Open Access
6 Citations
6,570 Views
15 Pages

16 February 2015

Silver nanoparticles supported on hierarchically porous silica and cobalt oxide monoliths have previously been shown to be catalytically active for the hydrogenation of common organic dyes in batch studies. This work presents a detailed investigation...

  • Article
  • Open Access
3 Citations
6,761 Views
23 Pages

A Computational Study of the Effects of Syk Activity on B Cell Receptor Signaling Dynamics

  • Reginald L. McGee,
  • Mariya O. Krisenko,
  • Robert L. Geahlen,
  • Ann E. Rundell and
  • Gregery T. Buzzard

11 February 2015

The kinase Syk is intricately involved in early signaling events in B cells and isrequired for proper response when antigens bind to B cell receptors (BCRs). Experimentsusing an analog-sensitive version of Syk (Syk-AQL) have better elucidated its rol...

  • Article
  • Open Access
9 Citations
9,889 Views
21 Pages

14 January 2015

Interleukin-6 (IL-6) is a systemic inflammatory mediator that triggers the human body’s acute phase response to trauma or inflammation. Although mathematical models for IL-6 signaling pathways have previously been developed, reactions that describe t...

  • Editorial
  • Open Access
1 Citations
5,682 Views
4 Pages

12 January 2015

Tissue engineering and, more broadly, regenerative medicine is moving into a phase where we are seeing potential therapies moving ‘slowly but surely’ from the laboratory into the clinic, i.e., from research to the clinic and into manufacturing. The n...

  • Article
  • Open Access
43 Citations
6,348 Views
21 Pages

8 January 2015

This paper gives an analysis of the efficacy of PFC strategies. PFC is widely used in industry for simple loops with constraint handling, as it is very simple and cheap to implement. However, the algorithm has had very little exposure in the mainstre...

  • Article
  • Open Access
26 Citations
14,923 Views
18 Pages

Mathematical Modeling of Pro- and Anti-Inflammatory Signaling in Macrophages

  • Shreya Maiti,
  • Wei Dai,
  • Robert C. Alaniz,
  • Juergen Hahn and
  • Arul Jayaraman

26 December 2014

Inflammation is a beneficial mechanism that is usually triggered by injury or infection and is designed to return the body to homeostasis. However, uncontrolled or sustained inflammation can be deleterious and has been shown to be involved in the eti...

  • Editorial
  • Open Access
1 Citations
5,707 Views
4 Pages

26 December 2014

Reaction-oriented research in flow chemistry and microreactor has been extensively focused upon in special journal issues and books. On a process level, this resembled the “drop-in” (retrofit) concept with the microreactor replacing a conventional (b...

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Processes - ISSN 2227-9717