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Processes, Volume 3, Issue 1

March 2015 - 14 articles

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Articles (14)

  • Article
  • Open Access
15 Citations
8,674 Views
18 Pages

20 March 2015

Fibrous materials are prominent among novel chromatographic supports for the separation and purification of biomolecules. In this work, strong anion exchange, quaternary ammonium (Q) functional fibrous adsorbents were evaluated with regards to their...

  • Article
  • Open Access
8 Citations
8,861 Views
26 Pages

16 March 2015

In this study, we present a novel modeling approach which combines ordinary differential equation (ODE) modeling with logical rules to simulate an archetype biochemical network, the human coagulation cascade. The model consisted of five differential...

  • Article
  • Open Access
5 Citations
6,655 Views
17 Pages

11 March 2015

A system is differentially flat if it is Lie–Bäcklund (L-B) equivalent to a free dynamical system that has dimensions equal to that of the input of the original system. Utilizing this equivalence, the problem of nonlinear model predictive control of...

  • Article
  • Open Access
13 Citations
7,467 Views
23 Pages

3 March 2015

Cell-free systems offer many advantages for the study, manipulation and modeling of metabolism compared to in vivo processes. Many of the challenges confronting genome-scale kinetic modeling can potentially be overcome in a cell-free system. For exam...

  • Review
  • Open Access
5 Citations
5,505 Views
25 Pages

17 February 2015

Performance assessment and retuning techniques for proportional-integral-derivative (PID) controllers are reviewed in this paper. In particular, we focus on techniques that consider deterministic performance and that use routine operating data (that...

  • Article
  • Open Access
6 Citations
6,420 Views
15 Pages

16 February 2015

Silver nanoparticles supported on hierarchically porous silica and cobalt oxide monoliths have previously been shown to be catalytically active for the hydrogenation of common organic dyes in batch studies. This work presents a detailed investigation...

  • Article
  • Open Access
3 Citations
6,525 Views
23 Pages

A Computational Study of the Effects of Syk Activity on B Cell Receptor Signaling Dynamics

  • Reginald L. McGee,
  • Mariya O. Krisenko,
  • Robert L. Geahlen,
  • Ann E. Rundell and
  • Gregery T. Buzzard

11 February 2015

The kinase Syk is intricately involved in early signaling events in B cells and isrequired for proper response when antigens bind to B cell receptors (BCRs). Experimentsusing an analog-sensitive version of Syk (Syk-AQL) have better elucidated its rol...

  • Article
  • Open Access
8 Citations
9,303 Views
21 Pages

14 January 2015

Interleukin-6 (IL-6) is a systemic inflammatory mediator that triggers the human body’s acute phase response to trauma or inflammation. Although mathematical models for IL-6 signaling pathways have previously been developed, reactions that describe t...

  • Editorial
  • Open Access
1 Citations
5,516 Views
4 Pages

12 January 2015

Tissue engineering and, more broadly, regenerative medicine is moving into a phase where we are seeing potential therapies moving ‘slowly but surely’ from the laboratory into the clinic, i.e., from research to the clinic and into manufacturing. The n...

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