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Children 2017, 4(7), 57; https://doi.org/10.3390/children4070057

The Association between Non-Alcoholic Fatty Liver Disease and Cardiovascular Risk in Children

Department of Woman, Child and General and Specialized Surgery, University of Studies of Campania “Luigi Vanvitelli”, 80138 Napoli, Italy
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Academic Editor: Lucia Pacifico
Received: 28 April 2017 / Revised: 28 June 2017 / Accepted: 3 July 2017 / Published: 7 July 2017
(This article belongs to the Special Issue Pediatric Nonalcoholic Fatty Liver Disease)
Full-Text   |   PDF [170 KB, uploaded 7 July 2017]

Abstract

The rising prevalence of childhood obesity in the past decades has made Non-Alcoholic Fatty Liver Disease (NAFLD) the most common cause of pediatric chronic liver disease worldwide. Currently, a growing body of evidence links NAFLD with cardiovascular disease (CVD) even at an early age. Data on the pediatric population have shown that NAFLD could represent an independent risk factor not only for cardiovascular events but also for early subclinical abnormalities in myocardial structure and function. Briefly, we review the current knowledge regarding the relationship between pediatric NAFLD and cardiovascular risk in an attempt to clarify our understanding of NAFLD as a possible cardiovascular risk factor in childhood. View Full-Text
Keywords: Non-Alcoholic Fatty Liver Disease; cardiovascular; risk; diseases; atherosclerosis; cardiac; abnormalities Non-Alcoholic Fatty Liver Disease; cardiovascular; risk; diseases; atherosclerosis; cardiac; abnormalities
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Di Sessa, A.; Umano, G.R.; Miraglia del Giudice, E. The Association between Non-Alcoholic Fatty Liver Disease and Cardiovascular Risk in Children. Children 2017, 4, 57.

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