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Biomolecules, Volume 11, Issue 3

March 2021 - 146 articles

 

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Cover Story: Circadian rhythm and the molecules involved in it, such as melanopsin and melatonin, play a key role in the eye to regulate homeostasis and even to treat some ocular conditions. As a result, many ocular pathologies, such as dry eye, corneal wound healing, cataracts, myopia, retinal diseases and glaucoma, are affected by this cycle. This review summarizes the current scientific literature about the influence of circadian patterns on the eye, focusing on its relationship with increased intraocular pressure and glaucoma. Further study is required on whether these treatments could improve their effect when posology is established in function of circadian patterns, as well as on if new drugs such as melatonin or its analogs, which are related to the circadian rhythm, not only could be used as the main treatment but as coadjutant, improving the circadian pattern or its antioxidant and antiangiogenic effect. View this paper

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