In the published [1] article, several statements describing the composition of lysophosphatidic acid (LPA) species in the gintonin fraction require clarification.
Originally, the manuscript stated that major LPA species include “C16:0, C18:0, and C18:1”. While this description reflects previously reported analytical findings [9,42], it may not fully represent the current consensus regarding relative abundance.
Recent interpretations suggest that unsaturated LPA species, particularly C18:2, are predominant in gintonin preparations, whereas saturated species such as C18:0 may be present at lower levels.
Accordingly, the following corrections have been made:
Correction in Abstract
Original:
Biochemical analyses have identified major LPA species within the gintonin fraction, including C16:0, C18:0, and C18:1, stabilized within a proteinaceous matrix that may influence receptor engagement kinetics.
Corrected:
Biochemical analyses have identified major LPA species within the gintonin fraction, including C16:0, C18:1, and other unsaturated LPA species such as C18:2 stabilized within a proteinaceous matrix that may influence receptor engagement kinetics.
Correction in Introduction
Original:
Biochemical analyses have demonstrated that the gintonin fraction contains specific LPA molecular species, including C16:0, C18:0, and C18:1, stabilized within a proteinaceous scaffold derived from ginseng tissue [9,42].
Corrected:
Biochemical analyses have demonstrated that the gintonin fraction contains specific LPA molecular species, including C16:0 and C18:1, and unsaturated species such as C18:2, stabilized within a proteinaceous scaffold derived from ginseng tissue [9,42].
Correction in Section 2.2
Original:
Mass spectrometric analyses of the gintonin-enriched fraction revealed the presence of multiple LPA molecular species, predominantly C16:0, C18:0, and C18:1 [9].
Corrected:
Mass spectrometric analyses of the gintonin-enriched fraction revealed the presence of multiple LPA molecular species, comprising multiple LPA species, including C16:0 and C18:1, and unsaturated species such as C18:2, which are considered predominant in recent analyses [9].
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
Reference
- Kim, K.-H.; Yoo, B.C. Gintonin as a Lysophosphatidic Acid-Enriched GPCR Ligand System: Molecular Architecture and Receptor Pharmacology in Panax ginseng. Biomolecules 2026, 16, 465. [Google Scholar] [CrossRef] [Scilit] [PubMed]
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