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Metabolites, Volume 4, Issue 2

June 2014 - 19 articles

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Articles (19)

  • Review
  • Open Access
226 Citations
17,726 Views
34 Pages

20 June 2014

Breath analysis is a promising field with great potential for non-invasive diagnosis of a number of disease states. Analysis of the concentrations of volatile organic compounds (VOCs) in breath with an acceptable accuracy are assessed by means of usi...

  • Article
  • Open Access
59 Citations
10,691 Views
18 Pages

Molar-Based Targeted Metabolic Profiling of Cyanobacterial Strains with Potential for Biological Production

  • Yudai Dempo,
  • Erika Ohta,
  • Yasumune Nakayama,
  • Takeshi Bamba and
  • Eiichiro Fukusaki

20 June 2014

Recently, cyanobacteria have become one of the most attractive hosts for biochemical production due to its high proliferative ability and ease of genetic manipulation. Several researches aimed at biological production using modified cyanobacteria hav...

  • Review
  • Open Access
14 Citations
7,101 Views
12 Pages

Surveillance of C-Allocation in Microalgal Cells

  • Heiko Wagner,
  • Anne Jungandreas,
  • Andrea Fanesi and
  • Christian Wilhelm

19 June 2014

When microalgae are exposed to changing environmental conditions, e.g., light-dark cycles or oscillations in nutrient availability (CO2, nitrogen, phosphate or silicate) they respond with metabolic changes in the carbon allocation pattern. Short tim...

  • Article
  • Open Access
156 Citations
16,938 Views
20 Pages

Influence of Missing Values Substitutes on Multivariate Analysis of Metabolomics Data

  • Piotr S. Gromski,
  • Yun Xu,
  • Helen L. Kotze,
  • Elon Correa,
  • David I. Ellis,
  • Emily Grace Armitage,
  • Michael L. Turner and
  • Royston Goodacre

16 June 2014

Missing values are known to be problematic for the analysis of gas chromatography-mass spectrometry (GC-MS) metabolomics data. Typically these values cover about 10%–20% of all data and can originate from various backgrounds, including analytical, co...

  • Article
  • Open Access
23 Citations
8,557 Views
13 Pages

30 May 2014

13C metabolic flux analysis (MFA) is a tool of metabolic engineering for investigation of in vivo flux distribution. A direct 13C enrichment analysis of intracellular free amino acids (FAAs) is expected to reduce time for labeling experiments of the...

  • Article
  • Open Access
25 Citations
7,899 Views
12 Pages

Metabolome Consistency: Additional Parazoanthines from the Mediterranean Zoanthid Parazoanthus Axinellae

  • Coralie Audoin,
  • Vincent Cocandeau,
  • Olivier P. Thomas,
  • Adrien Bruschini,
  • Serge Holderith and
  • Grégory Genta-Jouve

30 May 2014

Ultra-high pressure liquid chromatography coupled to high resolution mass spectrometry (UHPLC-MS/MS) analysis of the organic extract obtained from the Mediterranean zoanthid Parazoanthus axinellae yielded to the identification of five new parazoanthi...

  • Article
  • Open Access
12 Citations
7,440 Views
14 Pages

Adiponectin Isoforms Differentially Affect Gene Expression and the Lipidome of Primary Human Hepatocytes

  • Josef Wanninger,
  • Gerhard Liebisch,
  • Kristina Eisinger,
  • Markus Neumeier,
  • Charalampos Aslanidis,
  • Lisa Voggenreiter,
  • Rebekka Pohl,
  • Thomas S. Weiss,
  • Sabrina Krautbauer and
  • Christa Buechler

23 May 2014

Adiponectin (APN) exerts multiple beneficial effects in obesity and protects from liver injury. Different APN isoforms circulate in serum, and here, the effect of low molecular weight (LMW) and higher molecular weight (HMW) APN on primary human hepat...

  • Article
  • Open Access
35 Citations
9,223 Views
26 Pages

15 May 2014

Microorganisms are constantly exposed to rapidly changing conditions, under natural as well as industrial production scale environments, especially due to large-scale substrate mixing limitations. In this work, we present an experimental approach bas...

  • Article
  • Open Access
43 Citations
11,451 Views
21 Pages

Biotechnological Screening of Microalgal and Cyanobacterial Strains for Biogas Production and Antibacterial and Antifungal Effects

  • Opayi Mudimu,
  • Nataliya Rybalka,
  • Thorsten Bauersachs,
  • Jens Born,
  • Thomas Friedl and
  • Rüdiger Schulz

15 May 2014

Microalgae and cyanobacteria represent a valuable natural resource for the generation of a large variety of chemical substances that are of interest for medical research, can be used as additives in cosmetics and food production, or as an energy sour...

  • Article
  • Open Access
33 Citations
8,399 Views
19 Pages

9 May 2014

Exhaled volatile organic compounds (VOCs) are of interest for their potential to diagnose disease non-invasively. However, most breath VOC studies have analyzed single breath samples from an individual and assumed them to be wholly consistent represe...

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Metabolites - ISSN 2218-1989