You are currently viewing a new version of our website. To view the old version click .

Metabolites, Volume 10, Issue 9

September 2020 - 44 articles

Cover Story: Preterm birth (PTB) is a serious concern for neonate and maternal health, increasing the risk of mortality and morbidity. Several measures have been introduced for monitoring of PTB that offer just superficial information and are inadequate for confirmation of the PTB-causing agent. During pregnancy, hormonal/metabolic changes and consumption of high-protein/carbohydrate diets cause dysregulation, and gut microbiota alteration leads to dysbiosis of the vaginal microbiota profile. This dysbiosis of the vaginal microbiota, which occurs occasionally, is considered the most common cause of ascending vaginal infection. This dysbiosis directly impacts the production of pathogenic microbiota metabolites by changing the vaginal pH and inducing the release of proinflammatory cytokines (IL-6, IL-8, etc.) and immunological cells that might be responsible for PTB. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (44)

  • Article
  • Open Access
32 Citations
5,979 Views
11 Pages

11 September 2020

Tempe is a fermented soybean food from Indonesia, made by inoculating Rhizopus spp. onto cooked and dehulled soybean. Tempe has been a part of Indonesian culture since the 16th century and is now produced globally as a highly nutritious plant-based f...

  • Article
  • Open Access
8 Citations
3,879 Views
17 Pages

11 September 2020

Metabolic flux analysis requires both a reliable metabolic model and reliable metabolic profiles in characterizing metabolic reprogramming. Advances in analytic methodologies enable production of high-quality metabolomics datasets capturing isotopic...

  • Article
  • Open Access
20 Citations
4,751 Views
20 Pages

11 September 2020

Accumulation of biologically active metabolites is a specific feature of plant biochemistry, directing the use of plants in numerous applications in the pharmaceutical and food industries. Among these substances, the plethora of phenolic compounds ha...

  • Editorial
  • Open Access
2 Citations
2,673 Views
4 Pages

Metabolomics Applications in Children: A Right Way to Go

  • Maria Elisabetta Baldassarre and
  • Nicola Laforgia

8 September 2020

Metabolomics is a new science based on the study of the metabolome, representing the set of all the metabolites of a biological organism, which are the final products of its gene expression. Metabolomics appears to be a promising tool in perinatal st...

  • Article
  • Open Access
4 Citations
3,125 Views
10 Pages

Effect of Sample Storage Conditions on Measurements of Salivary Cotinine Levels

  • Fábio Renato Manzolli Leite,
  • Vibeke Baelum,
  • Julie Becker Pajaniaye,
  • Lisbeth Ann Abildtrup and
  • Rodrigo López

8 September 2020

Information on smoking exposure obtained with self-reports may be inaccurate. Cotinine has a large half-life and its salivary levels correlate well with plasmatic levels. The influence of storage conditions on the validity and precision of salivary c...

  • Article
  • Open Access
15 Citations
5,038 Views
22 Pages

8 September 2020

Multiple sclerosis (MS) is a neurodegenerative inflammatory disease where an autoimmune response to components of the central nervous system leads to a loss of myelin and subsequent neurological deterioration. People with MS can develop primary or se...

  • Article
  • Open Access
11 Citations
4,484 Views
16 Pages

Metabolic Characterization and Consequences of Mitochondrial Pyruvate Carrier Deficiency in Drosophila melanogaster

  • Chloé Simard,
  • Andréa Lebel,
  • Eric Pierre Allain,
  • Mohamed Touaibia,
  • Etienne Hebert-Chatelain and
  • Nicolas Pichaud

6 September 2020

In insect, pyruvate is generally the predominant oxidative substrate for mitochondria. This metabolite is transported inside mitochondria via the mitochondrial pyruvate carrier (MPC), but whether and how this transporter controls mitochondrial oxidat...

  • Review
  • Open Access
19 Citations
5,564 Views
30 Pages

5 September 2020

Globally, lung cancer is the most prevalent cancer type. However, screening and early detection is challenging. Previous studies have identified metabolites as promising lung cancer biomarkers. This systematic literature review and meta-analysis aime...

  • Article
  • Open Access
16 Citations
4,400 Views
20 Pages

4 September 2020

Microalgae produce specific chemicals indicative of stress and/or death. The aim of this study was to perform non-destructive monitoring of algal culture systems, in the presence and absence of grazers, to identify potential biomarkers of incipient p...

  • Article
  • Open Access
32 Citations
4,588 Views
15 Pages

An 1H NMR- and MS-Based Study of Metabolites Profiling of Garden Snail Helix aspersa Mucus

  • Nikolay G. Vassilev,
  • Svetlana D. Simova,
  • Miroslav Dangalov,
  • Lyudmila Velkova,
  • Venceslav Atanasov,
  • Aleksandar Dolashki and
  • Pavlinka Dolashka

2 September 2020

Metabolic profiling based on 1H nuclear magnetic resonance (NMR) spectroscopy was applied with the aim to investigate the functional role of the metabolites in lyophilized mucus from the garden snail Helix aspersa. Twenty metabolites were unambiguous...

of 5

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Metabolites - ISSN 2218-1989