Efficient Synthesis of Nα,N-Disubstituted α-Aminocarbohydroxamic Acids

Detlef, Geffken; Alf, Ploetz; Hans v., Zydowitz

doi:10.3797/scipharm.aut-02-31

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Article

24 November 2002

6 Pages

Efficient Synthesis of N^α,N-Disubstituted α-Aminocarbohydroxamic Acids

and

Department of Pharmaceutical Chemistry, University of Hamburg, Bundesstrasse 45,20 146 Hamburg, Germany

Author to whom correspondence should be addressed.

Sci. Pharm.2002, 70(4), 325-330;https://doi.org/10.3797/scipharm.aut-02-31

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Abstract

The title compounds 3 can be prepared in good yields by the reaction of N-substituted α-chlorocarbohydroxarnic acids 2 and primary amines in dirnethylacetarnide as solvent.

Keywords:

N-subst ituted a-chlorocarbohydroxamic acids, primary amines, dimethylacetarnide, N^α,N-disubstituted α-arninocarbohydroxamic acids

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