Simple Summary
The paper presents the synthesis of newly prepared derivatives of 6- methyl-2-phenyl-4-phenylamino-5-aminomethylpyrimidine and 5-methyl- 1,7- diphenyl-l,2,3,4-tetrahydropyrimido[4,5-d]pyrimidine and also the results of microbiological studies. Pyrimidopyrimidine derivatives prepared show a certain analogy in their chemical structure to quinolone structures and also- as it might have been expected - they inhibit to a large extent the growth of bacterial strains, in some cases better than some antibiotics and sulfonamides used at present.
Excerpt
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Our earlier works on synthesis and biological properties of the pyrimidine ring indicated that this system is extremely biologically active [...]
Keywords:
Pyrimidine, antibacterial action