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Diseases, Volume 4, Issue 1

March 2016 - 15 articles

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Articles (15)

  • Review
  • Open Access
3 Citations
5,275 Views
7 Pages

Pituitary-Adrenal Axis in Prader Willi Syndrome

  • Olivia S. Edgar,
  • Angela K. Lucas-Herald and
  • Mohamad Guftar Shaikh

19 January 2016

Purpose: Prader Willi syndrome (PWS) is a rare genetic condition that has concurrent endocrinological insufficiencies. The presence of growth hormone deficiency has been well documented, but adrenal insufficiency (AI) is not widely reported. A review...

  • Article
  • Open Access
11 Citations
7,304 Views
9 Pages

Phytoconstituents with Radical Scavenging and Cytotoxic Activities from Diospyros shimbaensis

  • Per Aronsson,
  • Joan J. E. Munissi,
  • Amra Gruhonjic,
  • Paul A. Fitzpatrick,
  • Göran Landberg,
  • Stephen S. Nyandoro and
  • Mate Erdelyi

15 January 2016

As part of our search for natural products having antioxidant and anticancer properties, the phytochemical investigation of Diospyros shimbaensis (Ebenaceae), a plant belonging to a genus widely used in East African traditional medicine, was carried...

  • Article
  • Open Access
4 Citations
7,392 Views
9 Pages

Obesity and Prader-Willi Syndrome Affect Heart Rate Recovery from Dynamic Resistance Exercise in Youth

  • Diobel M. Castner,
  • Susan J. Clark,
  • Daniel A. Judelson and
  • Daniela A. Rubin

15 January 2016

Following exercise, heart rate decline is initially driven by parasympathetic reactivation and later by sympathetic withdrawal. Obesity delays endurance exercise heart rate recovery (HRR) in both children and adults. Young people with Prader-Willi Sy...

  • Review
  • Open Access
62 Citations
17,168 Views
6 Pages

13 January 2016

Prader-Willi syndrome (PWS) is a neurodevelopmental disorder characterized by neonatal hypotonia, developmental delay/intellectual disability, and characteristic feeding behaviors with failure to thrive during infancy; followed by hyperphagia and exc...

  • Review
  • Open Access
11 Citations
5,615 Views
23 Pages

25 December 2015

Hepatocellular carcinoma (HCC) is one of the most common causes of cancer related mortality worldwide. The incidence of HCC has been increasing annually. Viral infection, alcohol usage, and other causes of cirrhosis have been identified as major risk...

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Diseases - ISSN 2079-9721