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Diseases, Volume 13, Issue 4

April 2025 - 37 articles

Cover Story: Bladder cancer is a prevalent malignancy worldwide, marked by a high recurrence rate, metastatic potential, and considerable socioeconomic impact. Usual therapeutic strategies are often associated with severe adverse effects, which can significantly affect patients' quality of life. In the pursuit of novel therapeutic approaches with reduced side effects, natural compounds have emerged as promising alternative or complementary options. This review explores the potential application of various bioactive phytochemicals—such as curcumin, resveratrol, epigallocatechin, and genistein—when used together with the conventional treatment of bladder cancer. Particular emphasis is placed on their capacity to modulate key molecular signaling pathways and mechanisms involved in cell survival, proliferation, migration, and apoptosis. View this paper
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Articles (37)

  • Article
  • Open Access
881 Views
11 Pages

Clinical Importance of B-Type Natriuretic Peptide Levels in Sinus Rhythm at 3 Months After Persistent Atrial Fibrillation Ablation

  • Jumpei Saito,
  • Toshihiko Matsuda,
  • Yui Koyanagi,
  • Katsuya Yoshihiro,
  • Yuma Gibo,
  • Soichiro Usumoto,
  • Wataru Igawa,
  • Toshitaka Okabe,
  • Naoei Isomura and
  • Masahiko Ochiai

21 April 2025

Background: B-type natriuretic peptide (BNP) levels after ablation have been associated with a risk of arrhythmia recurrence (AR) after atrial fibrillation (AF) ablation. In addition, baseline BNP levels were also predictors of AR after AF ablation....

  • Case Report
  • Open Access
664 Views
9 Pages

21 April 2025

Background: Almost all patients undergoing dialysis develop renal anemia and receive medicines such as erythropoietin and iron preparations. However, the conventional intravenous treatment with saccharated ferric oxide (SFO) is insufficient for these...

  • Systematic Review
  • Open Access
3,730 Views
30 Pages

Rabies Vaccination and Public Health Insights in the Extended Arabian Gulf and Saudi Arabia: A Systematic Scoping Review

  • Helal F. Hetta,
  • Khalid S. Albalawi,
  • Amal M. Almalki,
  • Nasser D. Albalawi,
  • Abdulmajeed S. Albalawi,
  • Suleiman M. Al-Atwi,
  • Saleh E. Alatawi,
  • Mousa J. Alharbi,
  • MeshaL F. Albalawi and
  • Ahmad A. Alharbi
  • + 3 authors

21 April 2025

Background and Aim: This systematic scoping review examines rabies-related incidents, interventions, and post-exposure immunoprophylaxis in the Arabian Gulf region and Saudi Arabian Peninsula. Methods: A comprehensive literature search was conducted...

  • Article
  • Open Access
1 Citations
751 Views
11 Pages

Correlation of Inflammatory Biomarkers and IgG4 Antibodies with Malaria in Cameroon’s Buea Municipality Children

  • Jerome Nyhalah Dinga,
  • Flora Ayah,
  • Emmanuel Fondungallah Anu,
  • Haowen Qin,
  • Stanley Dobgima Gamua,
  • Anthony Kukwah Tufon,
  • Magloire Essissima Amougou and
  • Rameshbabu Manyam

21 April 2025

Background: In recent decades, malaria has become a major worldwide public health problem in endemic countries, especially with children below five years. Malaria causes inflammation, and inflammatory biomarkers like α-1-glycoprotein (AGP) and C-reac...

  • Article
  • Open Access
791 Views
11 Pages

Clinical Trial: Effects of Autologous Dendritic Cell Administration on Renal Hemodynamics and Inflammatory Biomarkers in Diabetic Kidney Disease

  • Endang Drajat,
  • Aziza Ghanie Icksan,
  • Jonny Jonny,
  • Aditya Pratama Lokeswara,
  • Bhimo Aji Hernowo,
  • Elvita Rahmi Daulay and
  • Terawan Agus Putranto

21 April 2025

Background: Diabetic kidney disease (DKD) is a significant risk factor for End-Stage Renal Disease, with a high global incidence and mortality rate. Hyperglycemia in DKD induces inflammation, contributing to glomerular hyperfiltration, fibrosis, and...

  • Article
  • Open Access
2,084 Views
13 Pages

Exploring Self-Perceived Stress and Anxiety Throughout Pregnancy: A Longitudinal Study

  • Mar Miguel Redondo,
  • Cristina Liebana-Presa,
  • Javier Pérez-Rivera,
  • Cristian Martín-Vázquez,
  • Natalia Calvo-Ayuso and
  • Rubén García-Fernández

19 April 2025

Background: Anxiety and stress are common during pregnancy and can impact the health of the pregnant woman and the newborn. There is a lack of research focused on identifying weaknesses that promote equity in the care of pregnant women. The objective...

  • Article
  • Open Access
568 Views
9 Pages

Factors Influencing Physical Performance and Quality of Life in Post-COVID-19 Patients

  • Ajchamon Thammachai,
  • Patchareeya Amput and
  • Sirima Wongphon

19 April 2025

Background: This study aims to identify the factors related to demographic variables and physical performance associated with quality of life (QoL) in post-COVID-19 pa-tients who have recovered from mild infection and were not hospitalized. Methods:...

  • Brief Report
  • Open Access
782 Views
10 Pages

Possible Significance of Neutrophil–Hemoglobin Ratio in Differentiating Progressive Supranuclear Palsy from Depression: A Pilot Study

  • Michał Markiewicz,
  • Natalia Madetko-Alster,
  • Dagmara Otto-Ślusarczyk,
  • Karolina Duszyńska-Wąs,
  • Bartosz Migda,
  • Patryk Chunowski,
  • Marta Struga and
  • Piotr Alster

18 April 2025

Background: Research has associated chronic inflammation with the evolution of neurological and psychiatric disorders. Neurodegenerative diseases, including Parkinson’s Disease (PD), Alzheimer’s Disease (AD), and less common ones such as...

  • Article
  • Open Access
1,255 Views
11 Pages

False-Positive Galactomannan Test Results in Multiple Myeloma

  • Shingen Nakamura,
  • Yusaku Maeda,
  • Ryohei Sumitani,
  • Masahiro Oura,
  • Kimiko Sogabe,
  • Hikaru Yagi,
  • Shiro Fujii,
  • Takeshi Harada,
  • Ken-ichi Matsuoka and
  • Hirokazu Miki

17 April 2025

Background/Objectives: Invasive pulmonary aspergillosis (IA) is a common infectious disease in patients with hematological diseases. The prevention, early detection, and establishment of treatment strategies for IA are important. The serum galactoman...

  • Review
  • Open Access
2,905 Views
15 Pages

Neurogenic Bladder in Children with Myelomeningocele

  • Aleksandar Sič,
  • Borko Stojanović and
  • Miroslav Đorđević

17 April 2025

Myelomeningocele (MMC), a severe congenital anomaly resulting from neural tube closure defects, poses significant urological challenges necessitating specialized care. This review explores the intricate landscape of MMC within urological practice, ad...

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Diseases - ISSN 2079-9721Creative Common CC BY license