Infectious Disease Epidemiology 2024

A special issue of Diseases (ISSN 2079-9721). This special issue belongs to the section "Infectious Disease".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 545

Special Issue Editors


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Guest Editor
Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Jackson State University, Jackson, MS 39213, USA
Interests: COVID-19; monkeypox; sleep disorders; health disparities; breastfeeding; lead poisoning
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Guest Editor
Department of Biological Sciences, Northern Arizona University, Flagstaff, AZ 86011, USA
Interests: microbiology; immunology; infectious diseases; host-pathogen interactions; genomics; proteomics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Many developing countries are burdened with an influx of infectious diseases, including diarrhea, malaria, tuberculosis, and HIV/AIDS. Although vaccines provide protection against most infectious diseases, newer and emerging illnesses such as Ebola fever, SERS coronavirus disease, MARS, Nipah virus, Hantavirus, Dengue fever, Chikungunya, Rocky Mountain Spotted Fever, West Nile virus infection, etc., continue to represent prominent public health threats worldwide. Climate change and global warming are increasing the prevalence of many vector-borne diseases, including malaria, Dengue fever, Chagas disease, leishmaniasis, filariasis, onchocerciasis, schistosomiasis, and trypanosomiasis. Over time, many infectious organisms have adapted to the drugs designed to kill them, developing resistance to commonly used antimicrobials, fueled by improper medication or self-medication. There is a growing need to identify at-risk populations, social and environmental factors, and economic burdens and to prioritize resources accordingly. Mathematical modeling and GIS are also important tools in the prediction of infectious diseases, the identification of at-risk populations, and the evaluation of interventions.

For this Special Issue on “Infectious Disease Epidemiology”, we are seeking original articles and systematic reviews related to the global burden of infectious diseases, antimicrobial resistance, emerging diseases, social aspects and the economic burden of diseases, laboratory identification, clinical trials, community interventions, GIS application, and mathematical models. Depending on interest, this Special Issue may also be published as a physical book; free copies will be distributed to the contributing authors upon publication.

Prof. Dr. Amal K. Mitra
Prof. Dr. Fernando Monroy
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diseases is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • infectious diseases
  • global burden
  • disability-adjusted life years (DALY)
  • risk factors
  • community interventions
  • clinical trials
  • laboratory studies
  • drug resistance
  • GIS applications
  • cost-effective analysis
  • vaccine
  • mathematical models
  • social epidemiology

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Published Papers (1 paper)

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Research

12 pages, 603 KiB  
Article
Frequency of the Main Human Leukocyte Antigen A, B, DR, and DQ Loci Known to Be Associated with the Clearance or Persistence of Hepatitis C Virus Infection in a Healthy Population from the Southern Region of Morocco: A Preliminary Study
by Safa Machraoui, Khaoula Errafii, Ider Oujamaa, Moulay Yassine Belghali, Abdelmalek Hakmaoui, Saad Lamjadli, Fatima Ezzohra Eddehbi, Ikram Brahim, Yasmine Haida and Brahim Admou
Diseases 2024, 12(5), 106; https://doi.org/10.3390/diseases12050106 - 16 May 2024
Viewed by 238
Abstract
Hepatitis C Virus (HCV) infection represents a significant global health challenge, with its natural course largely influenced by the host’s immune response. Human Leukocyte Antigen (HLA) molecules, particularly HLA class I and II, play a crucial role in the adaptive immune response against [...] Read more.
Hepatitis C Virus (HCV) infection represents a significant global health challenge, with its natural course largely influenced by the host’s immune response. Human Leukocyte Antigen (HLA) molecules, particularly HLA class I and II, play a crucial role in the adaptive immune response against HCV. The polymorphism of HLA molecules contributes to the variability in immune response, affecting the outcomes of HCV infection. This study aims to investigate the frequency of HLA A, B, DR, and DQ alleles known to be associated with HCV clearance or persistence in a healthy Moroccan population. Conducted at the University Hospital Center Mohammed VI, Marrakech, this study spanned from 2015 to 2022 and included 703 healthy Moroccan individuals. HLA class I and II typing was performed using complement-dependent cytotoxicity and polymerase chain reaction-based methodologies. The results revealed the distinct patterns of HLA-A, B, DRB1, and DQB1 alleles in the Moroccan population. Notably, alleles linked to favorable HCV outcomes, such as HLA-DQB1*0301, DQB1*0501, and DRB1*1101, were more prevalent. Conversely, alleles associated with increased HCV susceptibility and persistence, such as HLA-DQB1*02 and DRB1*03, were also prominent. Gender-specific variations in allele frequencies were observed, providing insights into genetic influences on HCV infection outcomes. The findings align with global trends in HLA allele associations with HCV infection outcomes. The study emphasizes the role of host genetics in HCV infection, highlighting the need for further research in the Moroccan community, including HCV-infected individuals. The prevalence of certain HLA alleles, both protective and susceptibility-linked, underscores the potential for a national HLA data bank in Morocco. Full article
(This article belongs to the Special Issue Infectious Disease Epidemiology 2024)
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