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Diseases, Volume 11, Issue 1

March 2023 - 52 articles

Cover Story: Hantaan virus and relatives were long thought to constitute a homogenous group of rodent-infecting trisegmented negative-sense RNA viruses. Recent metagenomic studies revealed the considerable diversity of these viruses not only in rodents, but also in bats, eulipotyphlans, fish, and reptiles (silhouettes), necessitating the creation of a family, Hantaviridae, including multiple genera (italicized terms). Only orthohantaviruses are known to cause human diseases, i.e., hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Background: electron-microscopic images of orthohantavirus particles produced during Hantaan virus and Sin Nombre virus infections. View this paper
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Articles (52)

  • Article
  • Open Access
4 Citations
3,672 Views
12 Pages

22 March 2023

Background/Objective: This study aimed to investigate the effect of exposure to per- and polyfluoroalkyl substances (PFAS), a class of organic compounds utilized in commercial and industrial applications, on allostatic load (AL), a measure of chronic...

  • Systematic Review
  • Open Access
13 Citations
4,165 Views
16 Pages

Neutrophil to Lymphocyte Ratio as a Predictor of Postoperative Outcomes in Traumatic Brain Injury: A Systematic Review and Meta-Analysis

  • Andrew Nguyen,
  • Alexander Nguyen,
  • Timothy I. Hsu,
  • Harrison D. Lew,
  • Nithin Gupta,
  • Brandon Nguyen,
  • Akhil Mandavalli,
  • Michael J. Diaz and
  • Brandon Lucke-Wold

15 March 2023

(1) Introduction: Traumatic brain injury (TBI) is a leading cause of injury and mortality worldwide, carrying an estimated cost of $38 billion in the United States alone. Neutrophil to lymphocyte ratio (NLR) has been investigated as a standardized bi...

  • Article
  • Open Access
14 Citations
7,292 Views
12 Pages

The Possible Effect of the Long-Term Use of Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) on Hba1c and Lipid Profile in Type 2 Diabetes Mellitus: A Retrospective Study in KAUH, Jeddah, Saudi Arabia

  • Ghada M. A. Ajabnoor,
  • Kamal Talat Hashim,
  • Mohammed Meshari Alzahrani,
  • Abdullah Zeid Alsuheili,
  • Abdullah Fahad Alharbi,
  • Amani Matook Alhozali,
  • Sumia Enani,
  • Basmah Eldakhakhny and
  • Ayman Elsamanoudy

14 March 2023

(1) Background: Type 2 diabetes (T2DM) is a chronic metabolic disease with serious health complications. T2DM is associated with many chronic illnesses, including kidney failure, cardiovascular diseases (CVD), vision loss, and other related diseases....

  • Article
  • Open Access
9 Citations
46,175 Views
10 Pages

14 March 2023

We have previously shown that pitavastatin has the potential to be used to treat ovarian cancer, although relatively high doses are likely to be necessary. One solution to this problem is to identify drugs that are synergistic with pitavastatin, ther...

  • Article
  • Open Access
10 Citations
3,190 Views
13 Pages

Promising Antimicrobial Action of Sustained Released Curcumin-Loaded Silica Nanoparticles against Clinically Isolated Porphyromonas gingivalis

  • Adileh Shirmohammadi,
  • Solmaz Maleki Dizaj,
  • Simin Sharifi,
  • Shirin Fattahi,
  • Ramin Negahdari,
  • Mohammad Ali Ghavimi and
  • Mohammad Yousef Memar

Background. Porphyromonas gingivalis (P. gingivalis) has always been one of the leading causes of periodontal disease, and antibiotics are commonly used to control it. Numerous side effects of synthetic drugs, as well as the spread of drug resis...

  • Article
  • Open Access
6 Citations
3,579 Views
15 Pages

Three Perspectives on the Experience of Support for Family Caregivers in First Nations Communities

  • Amber Ward,
  • Laurie Buffalo,
  • Colleen McDonald,
  • Tanya L’Heureux,
  • Lesley Charles,
  • Cheryl Pollard,
  • Peter G Tian,
  • Sharon Anderson and
  • Jasneet Parmar

There is a dearth of research on how family caregivers are supported in First Nations. We interviewed family caregivers, health and community providers, and leaders in two Alberta First Nations Communities about their experiences of care and support...

  • Article
  • Open Access
6 Citations
3,034 Views
12 Pages

Background: Although the human immunodeficiency virus (HIV) is spatially heterogeneous in Ethiopia, current regional estimates of HIV prevalence hide the epidemic’s heterogeneity. A thorough examination of the prevalence of HIV infection using...

  • Review
  • Open Access
23 Citations
8,184 Views
11 Pages

Acute Traumatic Pain in the Emergency Department

  • Christian Zanza,
  • Tatsiana Romenskaya,
  • Marta Zuliani,
  • Fabio Piccolella,
  • Maria Bottinelli,
  • Giorgia Caputo,
  • Eduardo Rocca,
  • Antonio Maconi,
  • Gabriele Savioli and
  • Yaroslava Longhitano

Trauma is a major cause of mortality throughout the world. Traumatic pain—acute, sudden, or chronic—is defined as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage”. Patients&rsq...

  • Brief Report
  • Open Access
1 Citations
5,893 Views
6 Pages

Laparoscopic Surgery with Concomitant Hernia Repair and Cholecystectomy: An Alternative Approach to Everyday Practice

  • Paul Zarogoulidis,
  • Aris Ioannidis,
  • Marios Anemoulis,
  • Dimitrios Giannakidis,
  • Dimitris Matthaios,
  • Konstantinos Romanidis,
  • Konstantinos Sapalidis,
  • Lavrentios Papalavrentios and
  • Isaak Kesisoglou

Introduction: Concomitant surgeries have been performed previously in several centers with experience in laparoscopic surgeries. These surgeries are performed in one patient under one operation with anesthesia. Methods: We performed a retrospective u...

  • Article
  • Open Access
4 Citations
2,147 Views
10 Pages

Lipoprotein(a) and Its Autoantibodies in Association with Calcific Aortic Valve Stenosis

  • Anna L. Burdeynaya,
  • Olga I. Afanasieva,
  • Marat V. Ezhov,
  • Elena A. Klesareva,
  • Marina A. Saidova and
  • Sergey N. Pokrovsky

Aortic valve stenosis is the most common valvular heart disease in the Western world. Lipoprotein(a) (Lp(a)) is an independent risk factor of coronary heart disease (CHD) and calcific aortic valve stenosis (CAVS). The aim of this study was to assess...

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Diseases - ISSN 2079-9721