Third-Generation Cephalosporin Resistance in Intrinsic Colistin-Resistant Enterobacterales Isolated from Retail Meat
Abstract
1. Introduction
2. Results
2.1. Isolated ICR Enterobacterales
2.2. Antimicrobial Resistance Profiles of the Isolated ICR Enterobacterales
3. Discussion
4. Materials and Methods
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Bacteria | Total Pos. Samples (%) | Total No. of Isolates | Chicken (n = 103) | Pork (n = 103) | Beef (n = 104) | ||||
---|---|---|---|---|---|---|---|---|---|
Genus | Species | Pos. Samples (%) | No. of Isolates | Pos. Samples (%) | No. of Isolates | Pos. Samples (%) | No. of Isolates | ||
Serratia | liquefaciens | 194 (62.6) | 387 | 63 (61.2) | 118 | 64 (62.1) | 135 | 67 (64.4) | 134 |
marcescens | 25 (8.1) | 29 | 11 (10.7) | 13 | 6 (5.8) | 7 | 8 (7.7) | 9 | |
fonticola | 20 (6.5) | 21 | 11 (10.7) | 11 | 4 (3.8) | 5 | 5 (4.8) | 5 | |
plymuthica | 2 (1) | 3 | 1 (1) | 1 | 1 (1) | 2 | 0 | 0 | |
subtotal | 202 (65.2) | 440 | 68 (66) | 143 | 67 (65.0) | 149 | 67 (64.4) | 148 | |
Hafnia | alvei | 89 (28.7) | 136 | 17 (16.5) | 22 | 40 (38.8) | 62 | 32 (30.8) | 52 |
Proteus | penneri | 14 (4.5) | 18 | 11 (10.7) | 13 | 2 (1.9) | 3 | 1 (1) | 2 |
hauseri | 7 (2.3) | 9 | 4 (3.8) | 4 | 3 (2.9) | 5 | 0 | 0 | |
mirabilis | 7 (2.3) | 10 | 6 (5.8) | 9 | 1 (1) | 1 | 0 | 0 | |
vulgaris | 2 (1) | 2 | 1 (1) | 1 | 1 (1) | 1 | 0 | 0 | |
subtotal | 29 (9.4) | 39 | 21 (20.4) | 27 | 6 (5.8) | 10 | 1 (1) | 2 | |
Cedecea | davisae | 14 (4.5) | 22 | 11 (10.7) | 18 | 1 (1) | 2 | 2 (1.9) | 2 |
Providencia | rustigianii | 12 (3.9) | 12 | 12 (11.7) | 12 | 0 | 0 | 0 | 0 |
Morganella | morganii | 10 (3.2) | 11 | 7 (6.8) | 7 | 2 (1.9) | 2 | 1 (1) | 2 |
Bacteria | Resistance Profile | No. of Chicken Samples (No. of Isolates) | No. of Pork Samples (No. of Isolates) | No. of Beef Samples (No. of Isolates) | Total No. of Samples (Total No. of Isolates) |
---|---|---|---|---|---|
Serratia liquefaciens | CTX | 2 (3) | 1 (1) | 2 (2) | 5 (6) |
CTX-CAZ | 1 (1) | 1 (1) | |||
CTX-CHL | 1 (1) | 1 (1) | |||
Susceptible | 61 (115) | 61 (132) | 65 (132) | 187 (379) | |
Subtotal | 63 (118) | 64 (135) | 67 (134) | 199 (387) | |
Serratia marcescens | CAZ-TET-CIP-LVF | 1 (1) | 1 (1) | ||
CTX-NAL-CHL | 1 (1) | 1 (1) | |||
TET | 5 (5) | 4 (4) | 2 (2) | 11 (11) | |
TET-CHL | 1 (1) | 1 (1) | |||
Susceptible | 4 (6) | 2 (3) | 5 (6) | 11 (15) | |
Subtotal | 11 (13) | 6 (7) | 8 (9) | 25 (29) | |
Serratia fonticola | CTX | 5 (5) | 2 (2) | 3 (3) | 10 (10) |
Susceptible | 6 (7) | 2 (3) | 2 (2) | 10 (12) | |
Subtotal | 11 (12) | 4 (5) | 5 (5) | 19 (22) | |
Serratia plymuthica | Susceptible | 1 (1) | 1 (2) | 2 (3) | |
Hafnia alvei | CTX | 1 (1) | 4 (4) | 1 (1) | 6 (6) |
CAZ | 2 (2) | 2 (3) | 4 (5) | ||
TET | 1 (1) | 1 (1) | |||
CTX-CAZ | 3 (4) | 1 (1) | 4 (5) | ||
NAL | 1 (1) | 1 (1) | |||
CTX-CAZ-TET | 1 (1) | 1 (1) | |||
Susceptible | 16 (21) | 29 (50) | 27 (46) | 72 (117) | |
Subtotal | 17 (22) | 40 (62) | 32 (52) | 89 (136) | |
Proteus penneri | CHL | 1 (1) | 1 (1) | ||
CTX | 2 (2) | 2 (2) | |||
Susceptible | 9 (10) | 2 (3) | 1 (2) | 12 (15) | |
Subtotal | 11 (13) | 2 (3) | 1 (2) | 14 (18) | |
Proteus mirabilis | CHL | 1 (1) | 1 (1) | ||
SXT | 1 (2) | 1 (2) | |||
KAN-CHL-SXT | 1 (1) | 1 (1) | |||
Susceptible | 4 (6) | 0 | 0 | 4 (6) | |
Subtotal | 6 (9) | 1 (1) | 0 | 7 (10) | |
Proteus vulgaris | GEN-KAN-CHL-SXT | 1 (1) | 1 (1) | ||
Susceptible | 1 (1) | 0 | 1 (1) | ||
Subtotal | 1 (1) | 1 (1) | 2 (2) | ||
Proteus hauseri | Susceptible | 4 (4) | 3 (5) | 7 (9) | |
Cedecea davisae | TET | 1 (2) | 1 (2) | ||
Susceptible | 10 (16) | 1 (2) | 2 (2) | 13 (20) | |
Subtotal | 11 (18) | 1 (2) | 2 (2) | 14 (22) | |
Morganella morganii | CHL | 1 (1) | 1 (1) | ||
CTX | 1 (1) | 1 (1) | |||
TET | 2 (2) | 2 (2) | 4 (4) | ||
Susceptible | 3 (3) | 0 | 1 (2) | 4 (5) | |
Subtotal | 7 (7) | 2 (2) | 1 (2) | 10 (11) | |
Providencia rustigianii | Susceptible | 12 (12) | 0 | 0 | 12 (12) |
Total | 96 (229) | 89 (225) | 67 (206) | 252 (659) |
Bacteria | Strain No. | Source | Resistance Profile | Beta-Lactamase Gene Detected | |
---|---|---|---|---|---|
ESBL | AmpC | ||||
S. fonticola | CL-320 | Chicken | CTX | blafonA | |
S. fonticola | CL-398 | Pork | CTX | blafonA | |
S. fonticola | CL-402 | Pork | CTX | blafonA | |
S. fonticola | CL-513 | Chicken | CTX | blafonA | |
S. fonticola | CL-531 | Beef | CTX | blafonA | |
S. fonticola | CL-537 | Chicken | CTX | blafonA | |
S. fonticola | CL-559 | Chicken | CTX | blafonA | |
S. fonticola | CL-586 | Beef | CTX | blafonA | |
S. fonticola | CL-663 | Chicken | CTX | blafonA | |
S. fonticola | CL-1126 | Beef | CTX | blafonA | |
H. alvei | CL-41 | Beef | CTX | blaACC | |
H. alvei | CL-177 | Beef | CTX-TET | blaACC | |
H. alvei | CL-208 | Pork | CTX-CAZ | blaACC | |
H. alvei | CL-209 | Pork | CTX-CAZ | blaACC | |
H. alvei | CL-215 | Beef | CTX-CAZ | blaACC | |
H. alvei | CL-284 | Pork | CTX | blaACC | |
H. alvei | CL-338 | Chicken | CTX | blaACC | |
H. alvei | CL-607 | Pork | CTX-CAZ | blaACC | |
H. alvei | CL-698 | Pork | CTX | blaACC | |
H. alvei | CL-774 | Pork | CTX-CAZ | blaACC | |
H. alvei | CL-954 | Pork | CTX | blaACC | |
M. morganii | CL-277 | Chicken | CTX | blaDHA |
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Odoi, J.O.; Takayanagi, S.; Yossapol, M.; Sugiyama, M.; Asai, T. Third-Generation Cephalosporin Resistance in Intrinsic Colistin-Resistant Enterobacterales Isolated from Retail Meat. Antibiotics 2021, 10, 1437. https://doi.org/10.3390/antibiotics10121437
Odoi JO, Takayanagi S, Yossapol M, Sugiyama M, Asai T. Third-Generation Cephalosporin Resistance in Intrinsic Colistin-Resistant Enterobacterales Isolated from Retail Meat. Antibiotics. 2021; 10(12):1437. https://doi.org/10.3390/antibiotics10121437
Chicago/Turabian StyleOdoi, Justice Opare, Sayo Takayanagi, Montira Yossapol, Michiyo Sugiyama, and Tetsuo Asai. 2021. "Third-Generation Cephalosporin Resistance in Intrinsic Colistin-Resistant Enterobacterales Isolated from Retail Meat" Antibiotics 10, no. 12: 1437. https://doi.org/10.3390/antibiotics10121437
APA StyleOdoi, J. O., Takayanagi, S., Yossapol, M., Sugiyama, M., & Asai, T. (2021). Third-Generation Cephalosporin Resistance in Intrinsic Colistin-Resistant Enterobacterales Isolated from Retail Meat. Antibiotics, 10(12), 1437. https://doi.org/10.3390/antibiotics10121437