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Biosensors, Volume 11, Issue 2

February 2021 - 32 articles

Cover Story: The measurement of the chemical parameters of binding between cell adhesion molecules and extracellu-lar ligands using live-cell assays is a challenging task. Here, for the first time, we used a computer-controlled micropipette to measure cell adhesion on PLL-g-PEG-based surface coatings with various ligand densities to determine the dissociation constant of the integrin–RGD bond. We use a simple biophysical model to fit the weighted average of adhesion histograms. The results are confirmed by applying a resonant waveguide-based biosensor. Furthermore, we present a subpopulation analysis of the data emphasizing the single-cell capabili-ties of the method. We find that most cells are found in the weak adhesion range, while a growing, strongly adhered subpopulation appears with the increase of RGD surface density. View this paper.
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Articles (32)

  • Review
  • Open Access
27 Citations
8,293 Views
27 Pages

Nucleic Acid-Based Sensing Techniques for Diagnostics and Surveillance of Influenza

  • Samantha J. Courtney,
  • Zachary R. Stromberg and
  • Jessica Z. Kubicek-Sutherland

12 February 2021

Influenza virus poses a threat to global health by causing seasonal outbreaks as well as three pandemics in the 20th century. In humans, disease is primarily caused by influenza A and B viruses, while influenza C virus causes mild disease mostly in c...

  • Perspective
  • Open Access
18 Citations
6,721 Views
13 Pages

12 February 2021

Halophilic bacteria are remarkable organisms that have evolved strategies to survive in high saline concentrations. These bacteria offer many advances for microbial-based biotechnologies and are commonly used for industrial processes such as compatib...

  • Article
  • Open Access
6 Citations
2,766 Views
9 Pages

Simple Yeast-Direct Catalytic Fuel Cell Bio-Device: Analytical Results and Energetic Properties

  • Mauro Tomassetti,
  • Emanuele Dell’Aglio,
  • Mauro Castrucci,
  • Maria Pia Sammartino,
  • Luigi Campanella and
  • Corrado Di Natale

11 February 2021

This paper reports the analytical detection and energetic properties of a glucose-fed Direct Catalytic Fuel Cell (DCFC) operated in association with yeast cells (Saccharomyces Cerevisiae). The cell was tested in a potentiostatic mode, and the operati...

  • Review
  • Open Access
27 Citations
5,043 Views
28 Pages

Imprinted Polymers as Synthetic Receptors in Sensors for Food Safety

  • Rocio Arreguin-Campos,
  • Kathia L. Jiménez-Monroy,
  • Hanne Diliën,
  • Thomas J. Cleij,
  • Bart van Grinsven and
  • Kasper Eersels

11 February 2021

Foodborne illnesses represent high costs worldwide in terms of medical care and productivity. To ensure safety along the food chain, technologies that help to monitor and improve food preservation have emerged in a multidisciplinary context. These te...

  • Article
  • Open Access
26 Citations
4,367 Views
15 Pages

10 February 2021

An origami three-dimensional design of a paper-based potentiometric sensor is described. In its simplest form, this electrochemical paper-based analytical device (ePAD) is made from three small parts of the paper. Paper layers are folded on each othe...

  • Article
  • Open Access
20 Citations
4,401 Views
11 Pages

A Novel Enzyme-Based SPR Strategy for Detection of the Antimicrobial Agent Chlorophene

  • Gabriela Elizabeth Quintanilla-Villanueva,
  • Donato Luna-Moreno,
  • Edgar Allan Blanco-Gámez,
  • José Manuel Rodríguez-Delgado,
  • Juan Francisco Villarreal-Chiu and
  • Melissa Marlene Rodríguez-Delgado

9 February 2021

Chlorophene is an important antimicrobial agent present in disinfectant products which has been related to health and environmental effects, and its detection has been limited to chromatographic techniques. Thus, there is a lack of research that atte...

  • Article
  • Open Access
17 Citations
4,954 Views
15 Pages

Optimisation of an Electrochemical DNA Sensor for Measuring KRAS G12D and G13D Point Mutations in Different Tumour Types

  • Bukola Attoye,
  • Matthew J. Baker,
  • Fiona Thomson,
  • Chantevy Pou and
  • Damion K. Corrigan

5 February 2021

Circulating tumour DNA (ctDNA) is widely used in liquid biopsies due to having a presence in the blood that is typically in proportion to the stage of the cancer and because it may present a quick and practical method of capturing tumour heterogeneit...

  • Article
  • Open Access
21 Citations
5,726 Views
12 Pages

2D Nanomaterial, Ti3C2 MXene-Based Sensor to Guide Lung Cancer Therapy and Management

  • Mahek Sadiq,
  • Lizhi Pang,
  • Michael Johnson,
  • Venkatachalem Sathish,
  • Qifeng Zhang and
  • Danling Wang

4 February 2021

Major advances in cancer control can be greatly aided by early diagnosis and effective treatment in its pre-invasive state. Lung cancer (small cell and non-small cell) is a leading cause of cancer-related deaths among both men and women around the wo...

  • Review
  • Open Access
14 Citations
4,499 Views
16 Pages

Ethanol Biofuel Cells: Hybrid Catalytic Cascades as a Tool for Biosensor Devices

  • Jefferson Honorio Franco,
  • Shelley D. Minteer and
  • Adalgisa R. De Andrade

4 February 2021

Biofuel cells use chemical reactions and biological catalysts (enzymes or microorganisms) to produce electrical energy, providing clean and renewable energy. Enzymatic biofuel cells (EBFCs) have promising characteristics and potential applications as...

  • Review
  • Open Access
27 Citations
7,829 Views
18 Pages

31 January 2021

Cyclic adenosine monophosphate (cAMP) plays a key role in signal transduction pathways as a second messenger. Studies on the cAMP dynamics provided useful scientific insights for drug development and treatment of cAMP-related diseases such as some ca...

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Biosensors - ISSN 2079-6374