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Journal of Clinical Medicine, Volume 3, Issue 2

June 2014 - 20 articles

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Articles (20)

  • Article
  • Open Access
6 Citations
7,387 Views
11 Pages

First Trimester Aneuploidy Screening Markers in Women with Pre-Gestational Diabetes Mellitus

  • Padmalatha Gurram,
  • Peter Benn,
  • James Grady,
  • Anne-Marie Prabulos and
  • Winston Campbell

8 May 2014

Objective: To investigate whether maternal serum pregnancy associated plasma protein-A (PAPP-A), total β human chorionic gonadotropin (hCG) levels and nuchal translucency (NT) measurements differ in women with pre-gestational diabetes mellitus (PGDM)...

  • Review
  • Open Access
69 Citations
23,915 Views
27 Pages

7 May 2014

Currently, two-thirds of American adults are overweight or obese. This high prevalence of overweight/obesity negatively affects the health of the population, as obese individuals tend to develop several chronic diseases, such as type 2 diabetes and c...

  • Editorial
  • Open Access
8 Citations
5,835 Views
13 Pages

6 May 2014

In this paper, all possible clinical applications of circulating mRNA and miRNA for non-invasive prenatal diagnosis appearing in the medical literature so far are described. Data from the literature have also been reported and commented on along with...

  • Article
  • Open Access
9 Citations
7,645 Views
8 Pages

Prenatal Isolated Ventricular Septal Defect May Not Be Associated with Trisomy 21

  • Ori Shen,
  • Sari Lieberman,
  • Benjamin Farber,
  • Daniel Terner,
  • Amnon Lahad and
  • Ephrat Levy-Lahad

23 April 2014

The aim of this study was to examine if isolated fetal ventricular septal defect (VSD) is associated with trisomy 21. One hundred twenty six cases with prenatal VSD diagnosed by a pediatric cardiologist were reviewed. Cases with known risk factors fo...

  • Article
  • Open Access
7 Citations
7,377 Views
16 Pages

Cortical Volume Alterations in Conduct Disordered Adolescents with and without Bipolar Disorder

  • Rene L. Olvera,
  • David C. Glahn,
  • Louise O'Donnell,
  • Carrie E. Bearden,
  • Jair C. Soares,
  • Anderson M. Winkler and
  • Steven R. Pliszka

16 April 2014

Background: There is increasing evidence that bipolar disorder (BD) and conduct disorder (CD) are co-occurring disorders. Magnetic resonance imaging has revealed differences in the structure and function of the frontal cortex in these disorders when...

  • Review
  • Open Access
7 Citations
10,918 Views
28 Pages

Beyond Trisomy 21: Additional Chromosomal Anomalies Detected through Routine Aneuploidy Screening

  • Amy Metcalfe,
  • Catriona Hippman,
  • Melanie Pastuck and
  • Jo-Ann Johnson

8 April 2014

Prenatal screening is often misconstrued by patients as screening for trisomy 21 alone; however, other chromosomal anomalies are often detected. This study aimed to systematically review the literature and use diagnostic meta-analysis to derive poole...

  • Article
  • Open Access
16 Citations
6,863 Views
14 Pages

Hyponatremia: A Risk Factor for Early Overt Encephalopathy after Transjugular Intrahepatic Portosystemic Shunt Creation

  • Jonathan Merola,
  • Noami Chaudhary,
  • Meng Qian,
  • Alexander Jow,
  • Katherine Barboza,
  • Hearns Charles,
  • Lewis Teperman and
  • Samuel Sigal

4 April 2014

Hepatic encephalopathy (HE) is a frequent complication in cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt (TIPS). Hyponatremia (HN) is a known contributing risk factor for the development of HE. Predictive factors, especia...

  • Review
  • Open Access
8 Citations
7,801 Views
15 Pages

The Power and the Promise of Cell Reprogramming: Personalized Autologous Body Organ and Cell Transplantation

  • Ana Belen Alvarez Palomo,
  • Michaela Lucas,
  • Rodney J. Dilley,
  • Samuel McLenachan,
  • Fred Kuanfu Chen,
  • Jordi Requena,
  • Marti Farrera Sal,
  • Andrew Lucas,
  • Inaki Alvarez and
  • Dolores Jaraquemada
  • + 1 author

4 April 2014

Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) or direct reprogramming to desired cell types are powerful and new in vitro methods for the study of human disease, cell replacement therapy, and drug development. Both methods to...

  • Article
  • Open Access
4 Citations
7,197 Views
11 Pages

Can Characteristics of Reciprocal Translocations Predict the Chance of Transferable Embryos in PGD Cycles?

  • Elsbeth Dul,
  • Jannie Van Echten-Arends,
  • Henk Groen,
  • Peter Kastrop,
  • Lucie Amory-van Wissen,
  • John Engelen,
  • Jolande Land,
  • Edith Coonen and
  • Conny Van Ravenswaaij-Arts

2 April 2014

Translocation carriers have an increased risk of miscarriage or the birth of a child with congenital anomalies. Preimplantation genetic diagnosis (PGD) is performed in translocation carriers to select for balanced embryos and, thus, increase the chan...

  • Opinion
  • Open Access
2 Citations
10,335 Views
14 Pages

28 March 2014

Pediatric bipolar disorder is a diagnosis that arose in the mid 1990s in the USA and has mostly remained confined to that nation. In this article a young American man (under a pseudonym) describes his experience of having the diagnosis throughout his...

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J. Clin. Med. - ISSN 2077-0383Creative Common CC BY license