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Journal of Clinical Medicine, Volume 3, Issue 1

2014 March - 19 articles

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Articles (19)

  • Article
  • Open Access
11,156 Views
13 Pages

Pediatric Bipolar Disorder: Subtype Trend and Impact of Behavioral Comorbidities

  • Thiyagu Rajakannan,
  • Julie M. Zito,
  • Mehmet Burcu and
  • Daniel J. Safer

20 March 2014

The diagnosis of pediatric bipolar disorder (PBD) has increased dramatically in community-treated youth in the past 20 years. No previous study has assessed the trend in PBD subtype diagnoses or the impact of clinician-reported behavioral comorbiditi...

  • Article
  • Open Access
1 Citations
7,517 Views
11 Pages

20 March 2014

The Chinese inland, where low child obesity and overweight rates were reported in earlier studies, has recently experienced rapid economy changes. This may impact children’s health. In the present study, we investigated the obesity rate, metabolic he...

  • Review
  • Open Access
36 Citations
20,171 Views
30 Pages

17 March 2014

Preimplantation genetic diagnosis was developed nearly a quarter-century ago as an alternative form of prenatal diagnosis that is carried out on embryos. Initially offered for diagnosis in couples at-risk for single gene genetic disorders, such as c...

  • Article
  • Open Access
5 Citations
9,113 Views
13 Pages

Effectiveness of Proadrenomedullin Enhanced CURB65 Score Algorithm in Patients with Community-Acquired Pneumonia in “Real Life”, an Observational Quality Control Survey

  • Daniel Widmer,
  • Daniel Drozdov,
  • Kristina Rüegger,
  • Alexander Litke,
  • Birsen Arici,
  • Katharina Regez,
  • Merih Guglielmetti,
  • Ursula Schild,
  • Antoinette Conca and
  • Werner C. Albrich
  • + 9 authors

14 March 2014

Background: An intervention trial found a trend for shorter length of stay (LOS) in patients with community-acquired pneumonia (CAP) when the CURB65 score was combined with the prognostic biomarker proadrenomedullin (ProADM) (CURB65-A). However, the...

  • Article
  • Open Access
10 Citations
7,888 Views
12 Pages

Circadian Phase Preference in Pediatric Bipolar Disorder

  • Kerri L. Kim,
  • Alexandra B. Weissman,
  • Megan E. Puzia,
  • Grace K. Cushman,
  • Karen E. Seymour,
  • Ezra Wegbreit,
  • Mary A. Carskadon and
  • Daniel P. Dickstein

11 March 2014

Pediatric bipolar disorder (BD) rates have notably increased over the past three decades. Given the significant morbidity and mortality associated with BD, efforts are needed to identify factors useful in earlier detection to help address this seriou...

  • Article
  • Open Access
9,124 Views
15 Pages

Improving Clinical Prediction of Bipolar Spectrum Disorders in Youth

  • Thomas W. Frazier,
  • Eric A. Youngstrom,
  • Mary A. Fristad,
  • Christine Demeter,
  • Boris Birmaher,
  • Robert A. Kowatch,
  • L. Eugene Arnold,
  • David Axelson,
  • Mary K. Gill and
  • Robert L. Findling
  • + 1 author

10 March 2014

This report evaluates whether classification tree algorithms (CTA) may improve the identification of individuals at risk for bipolar spectrum disorders (BPSD). Analyses used the Longitudinal Assessment of Manic Symptoms (LAMS) cohort (629 youth, 148...

  • Review
  • Open Access
11 Citations
9,151 Views
22 Pages

Frontotemporal White Matter in Adolescents with, and at-Risk for, Bipolar Disorder

  • Sonja M. C. De Zwarte,
  • Jennifer A. Y. Johnston,
  • Elizabeth T. Cox Lippard and
  • Hilary P. Blumberg

10 March 2014

Frontotemporal neural systems are highly implicated in the emotional dysregulation characteristic of bipolar disorder (BD). Convergent genetic, postmortem, behavioral and neuroimaging evidence suggests abnormalities in the development of frontotempor...

  • Review
  • Open Access
16 Citations
8,817 Views
19 Pages

Towards a Treatment of Stress Urinary Incontinence: Application of Mesenchymal Stromal Cells for Regeneration of the Sphincter Muscle

  • Wilhelm K. Aicher,
  • Melanie L. Hart,
  • Jan Stallkamp,
  • Mario Klünder,
  • Michael Ederer,
  • Oliver Sawodny,
  • Martin Vaegler,
  • Bastian Amend,
  • Karl D. Sievert and
  • Arnulf Stenzl

24 February 2014

Stress urinary incontinence is a significant social, medical, and economic problem. It is caused, at least in part, by degeneration of the sphincter muscle controlling the tightness of the urinary bladder. This muscular degeneration is characterized...

  • Article
  • Open Access
18 Citations
10,231 Views
15 Pages

14 February 2014

As new technologies enable the development of non-invasive prenatal diagnosis (NIPD) for cystic fibrosis (CF), research examining stakeholder views is essential for the preparation of implementation strategies. Here, we compare the views of potential...

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J. Clin. Med. - ISSN 2077-0383