Microarrays, Volume 1, Issue 2

September 2012 - 3 articles

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Articles (3)

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Article

10 Citations

7,488 Views

12 Pages

Development and Optimization of a Thrombin Sandwich Aptamer Microarray

Anna Meneghello,
Alice Sosic,
Agnese Antognoli,
Erica Cretaio and
Barbara Gatto

Microarrays2012, 1(2), 95-106;https://doi.org/10.3390/microarrays1020095

8 August 2012

A sandwich microarray employing two distinct aptamers for human thrombin has been optimized for the detection of subnanomolar concentrations of the protein. The aptamer microarray demonstrates high specificity for thrombin, proving that a two-site bi...

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Article

4 Citations

10,003 Views

11 Pages

Quality Visualization of Microarray Datasets Using Circos

Martin Koch and
Michael Wiese

Microarrays2012, 1(2), 84-94;https://doi.org/10.3390/microarrays1020084

7 August 2012

Quality control and normalization is considered the most important step in the analysis of microarray data. At present there are various methods available for quality assessments of microarray datasets. However there seems to be no standard visualiza...

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Review

26 Citations

14,723 Views

20 Pages

Data Analysis Strategies for Protein Microarrays

Paula Díez,
Noelia Dasilva,
María González-González,
Sergio Matarraz,
Juan Casado-Vela,
Alberto Orfao and
Manuel Fuentes

Microarrays2012, 1(2), 64-83;https://doi.org/10.3390/microarrays1020064

6 August 2012

Microarrays constitute a new platform which allows the discovery and characterization of proteins. According to different features, such as content, surface or detection system, there are many types of protein microarrays which can be applied for the...

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