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Appl. Sci. 2016, 6(11), 365;

Advanced Microbubbles as a Multifunctional Platform Combining Imaging and Therapy

Department of Ultrasonic Diagnosis, The Second Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China
These authors contributed equally to this work.
Authors to whom correspondence should be addressed.
Academic Editor: Kohji Masuda
Received: 6 October 2016 / Revised: 9 November 2016 / Accepted: 11 November 2016 / Published: 21 November 2016
(This article belongs to the Special Issue Biomedical Ultrasound)
Full-Text   |   PDF [2586 KB, uploaded 21 November 2016]   |  


Microbubbles as traditional ultrasound contrast agents have seen tremendous developments and bio-applications in the past decades. Due to their outstanding performance, advanced microbubbles as a multifunctional platform combining both imaging and therapy have been increasingly attracting attention. Associated with ultrasound-mediated stimuli, targeting drug transportation with high precision can be established and, as a consequence, a synergistic treatment strategy may prevail, which implies a bright perspective for this brand-new technology. This perspective article will summarize the latest developments on the advanced microbubbles, and review their emerging biomedical applications for the vast community of both applied ultrasound and functional ultrasound-based materials. View Full-Text
Keywords: ultrasound; microbubbles; multifunctional; UTMD; targeted therapy ultrasound; microbubbles; multifunctional; UTMD; targeted therapy

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Ni, X.; Ye, J.; Wang, L.; Xu, S.; Zou, C.; Yang, Y.; Liu, Z. Advanced Microbubbles as a Multifunctional Platform Combining Imaging and Therapy. Appl. Sci. 2016, 6, 365.

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