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Medical Sciences, Volume 10, Issue 1

2022 March - 20 articles

Cover Story: Background: The objective of this study was to assess if preoperative use of ARNI is associated with an increased VS after OHT or LVAD implantation and its relationship with 30-day mortality. Methods: A retrospective review of perioperative data, between January 2016 and December 2017, from 73 OHT and LVAD surgery adult patients was performed. Results: Preoperative use of an ARNI compared to that of other RAS blockers was not significantly associated with VS (p = 0.72). Preoperative treatment with ARNI was associated with a significantly lower rate of death compared to the absence of treatment (p = 0.009 ARNI). Conclusions: Preoperative use of ARNI was not significantly associated with development of VS in patients undergoing OHT or LVAD surgery. Furthermore, a significant 30-day survival benefit was determined with efficient ARNi before surgery. View this paper
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Articles (20)

  • Article
  • Open Access
1 Citations
3,731 Views
13 Pages

17 March 2022

Autophagy is a known mechanism of cells under internal stress that regulates cellular function via internal protein recycling and the cleaning up of debris, leading to healthy live cells. However, the stimulation of autophagy by external factors such...

  • Systematic Review
  • Open Access
15 Citations
5,746 Views
13 Pages

Parathyroid Allotransplantation: A Systematic Review

  • Jaimie L. H. Zhang,
  • Natasha M. Appelman-Dijkstra and
  • Abbey Schepers

15 March 2022

Background: To date, there is no satisfactory treatment for patients with calcium and vitamin D supplementation refractive hypoparathyroidism. Parathyroid allotransplantation by design is a one-time cure through its restoration of the parathyroid fun...

  • Article
  • Open Access
1 Citations
2,832 Views
7 Pages

The Dorsomedian Ligamentous Strand: An Evaluation In Vivo with Epiduroscopy

  • Maurizio Marchesini,
  • Eleonora Schiappa and
  • William Raffaeli

Several anatomical studies have described the morphology of the spinal space; however, researchers do not all agree on the presence of the dorsomedian ligamentous strand (DLS), which divides the epidural space. The possible existence of this structur...

  • Article
  • Open Access
16 Citations
4,560 Views
14 Pages

Anogeissus acuminata is used to treat wounds, diarrhoea, dysentery, and skin ailments. However, its hepatoprotective effect against ethanol-induced liver damage is yet to be reported. The phenolic-enriched ethyl acetate fraction of Anogeissus acumina...

  • Review
  • Open Access
22 Citations
5,724 Views
10 Pages

US Cancer Screening Recommendations: Developments and the Impact of COVID-19

  • Adam Barsouk,
  • Kalyan Saginala,
  • John Sukumar Aluru,
  • Prashanth Rawla and
  • Alexander Barsouk

The USPSTF and ACS recommend screening for breast, cervical, colorectal, and lung cancers. Rates of cancer screening, diagnosis, and treatment decreased significantly in the US and other developed nations during the height of the COVID-19 pandemic an...

  • Review
  • Open Access
21 Citations
8,526 Views
36 Pages

Overcoming Drug Resistance in Advanced Prostate Cancer by Drug Repurposing

  • Hisham F. Bahmad,
  • Timothy Demus,
  • Maya M. Moubarak,
  • Darine Daher,
  • Juan Carlos Alvarez Moreno,
  • Francesca Polit,
  • Olga Lopez,
  • Ali Merhe,
  • Wassim Abou-Kheir and
  • Yumna Omarzai
  • + 2 authors

18 February 2022

Prostate cancer (PCa) is the second most common cancer in men. Common treatments include active surveillance, surgery, or radiation. Androgen deprivation therapy and chemotherapy are usually reserved for advanced disease or biochemical recurrence, su...

  • Article
  • Open Access
6 Citations
4,122 Views
12 Pages

Dynamics in Morbidity Markers and Cytological Observations Made in Urine of Schistosoma haematobium-Infected Children: Pre- and Post-Praziquantel Treatment in an Endemic Setting

  • Patience B. Tetteh-Quarcoo,
  • Asamoah Ampong,
  • Nicholas T. K. D. Dayie,
  • John Ahenkorah,
  • Emilia A. Udofia,
  • Emmanuel Afutu,
  • Robert Aryee,
  • Benjamin P. Niriwa,
  • Fleischer C. N. Kotey and
  • Patrick F. Ayeh-Kumi
  • + 1 author

17 February 2022

Background: Schistosomiasis is a neglected tropical disease caused by helminths of the genus Schistosoma. Morbidity markers and cytological observations such as squamous metaplastic cells, inflammatory cells, and hyperkeratotic cells in the urine of...

  • Article
  • Open Access
12 Citations
5,700 Views
14 Pages

Recent Considerations on Gaming Console Based Training for Multiple Sclerosis Rehabilitation

  • Antonio Celesti,
  • Vincenzo Cimino,
  • Antonino Naro,
  • Simona Portaro,
  • Maria Fazio,
  • Massimo Villari and
  • Rocco Salvatore Calabró

11 February 2022

Multiple Sclerosis (MS) is a well-known, chronic demyelinating disease of the Central Nervous System (CNS) and one of the most common causes of disability in young adults. In this context, one of the major challenges in patients’ rehabilitation...

  • Review
  • Open Access
27 Citations
7,724 Views
14 Pages

9 February 2022

Ultrasonography is becoming the favored hemodynamic monitoring utensil of emergentologists, anesthesiologists and intensivists. While the roles of ultrasound grow and evolve, many clinical applications of ultrasound stem from qualitative, image-based...

  • Article
  • Open Access
2 Citations
2,960 Views
8 Pages

8 February 2022

Introduction: The American College of Rheumatology (ACR) criteria, and more recently the revised ACR criteria (rACR), are a scoring system developed to aid in the diagnosis of giant cell arteritis (GCA). Our aim was to investigate the value of the no...

  • Article
  • Open Access
10 Citations
5,386 Views
10 Pages

Preliminary Investigation into Plasmodium-like Piroplasms (Babesia/Theileria) among Cattle, Dogs and Humans in A Malaria-Endemic, Resource-Limited Sub-Saharan African City

  • Patrick F. Ayeh-Kumi,
  • Irene A. Owusu,
  • Patience B. Tetteh-Quarcoo,
  • Nicholas T. K. D. Dayie,
  • Kevin Kofi Adutwum-Ofosu,
  • Seth K. Amponsah,
  • Emilia A. Udofia,
  • Emmanuel Afutu,
  • Simon K. Attah and
  • John Ahenkorah
  • + 6 authors

3 February 2022

Babesia and Theileria are protozoan parasites belonging to the order piroplasmida, transmitted by hard ticks, and can cause diseases known as piroplasmosis. Human infections are usually asymptomatic, except in immuno-compromised persons who present m...

  • Article
  • Open Access
5 Citations
3,677 Views
7 Pages

Psoriasis in Patients Attending a Large HIV Clinic in Trinidad

  • Robert Jeffrey Edwards,
  • Leon Omari Lavia,
  • Jonathan Edwards and
  • Gregory Boyce

29 January 2022

The data on psoriasis in persons infected with HIV in the Caribbean is sparse. A cross-sectional study was conducted on patients attending the HIV Clinic diagnosed with psoriasis where sociodemographic data and data on the pattern of psoriasis were c...

  • Article
  • Open Access
36 Citations
5,083 Views
16 Pages

Amelioration of Cadmium-Induced Oxidative Damage in Wistar Rats by Vitamin C, Zinc and N-Acetylcysteine

  • Venkataramanaiah Poli,
  • Renuka Madduru,
  • Yenukolu Aparna,
  • Vimala Kandukuri and
  • Srinivasulu Reddy Motireddy

26 January 2022

The present study was performed to determine the protective effects of vitamin C, zinc, and N-acetylcysteine, individually or in combination with Cd, to monitor their amelioration capability against Cd-induced oxidative damage in Wistar rats. We inve...

  • Review
  • Open Access
8 Citations
4,693 Views
13 Pages

Emerging Tools to Capture Self-Reported Acute and Chronic Pain Outcome in Children and Adolescents: A Literature Review

  • Alexandra Turnbull,
  • Dean Sculley,
  • Derek Santos,
  • Mohammed Maarj,
  • Lachlan Chapple,
  • Xavier Gironès,
  • Antoni Fellas and
  • Andrea Coda

25 January 2022

The advancement of digital health provides strategic and cost-effective opportunities for the progression of health care in children and adolescents. It is important for clinicians to be aware of the potential of emerging pain outcome measures and em...

  • Systematic Review
  • Open Access
9 Citations
4,888 Views
10 Pages

A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis

  • Kevin Kyungmin Lee,
  • Osman Rahimi,
  • Charlie Kyungchan Lee,
  • Amaan Shafi and
  • Dalia Hawwass

21 January 2022

Background: Multiple studies have investigated the correlations of mortality, mechanical ventilation, and intensive care unit (ICU) admissions with CAC scores. This analysis overviews the prognostic capability of CAC scoring in mortality, mechanical...

  • Article
  • Open Access
16 Citations
4,008 Views
17 Pages

RhoA, Claudin 18, and c-MET in Gastric Cancer: Clinicopathological Characteristics and Prognostic Significance in Curative Resected Patients

  • Marina Alessandra Pereira,
  • Marcus Fernando Kodama Pertille Ramos,
  • Andre Roncon Dias,
  • Leonardo Cardili,
  • Renan Ribeiro e Ribeiro,
  • Tiago Biachi de Castria,
  • Bruno Zilberstein,
  • Sergio Carlos Nahas,
  • Ulysses Ribeiro and
  • Evandro Sobroza de Mello

29 December 2021

Background: Recently, markers related to molecular classification were suggested as promising therapeutic targets for treatment and prediction of prognosis in gastric cancer (GC), including c-MET, RhoA, and Claudin-18 (CLDN18). This study aimed to in...

  • Hypothesis
  • Open Access
20 Citations
14,586 Views
15 Pages

Nitric Oxide: The Missing Factor in COVID-19 Severity?

  • Alexandros Nikolaidis,
  • Ron Kramer and
  • Sergej Ostojic

23 December 2021

Coronavirus disease 2019 (COVID-19) is a contagious respiratory and vascular disease that continues to spread among people around the world, mutating into new strains with increased transmission rates, such as the delta variant. The scientific commun...

  • Article
  • Open Access
16 Citations
4,810 Views
10 Pages

ARNI Pre-Operative Use and Vasoplegic Syndrome in Patients Undergoing Heart Transplantation or Left Ventricular Assist Device Surgery

  • Lamis Haider,
  • Elisabeth Hugon-Vallet,
  • Jean Philippe Constantin,
  • Zakaria Riad,
  • Laurent Sebbag and
  • Nathan Mewton

21 December 2021

Background: Vasoplegic syndrome after orthotopic heart transplantation (OHT) or left ventricular assist device (LVAD) implantation is a rare but highly lethal syndrome with complex etiologies. The objective of this study was to assess if the preopera...

  • Article
  • Open Access
4 Citations
5,213 Views
11 Pages

Safety of Insulin Degludec/Insulin Aspart in Patients with Diabetes Mellitus over a Period of 1 Year during Routine Clinical Care in India: SMART (Study of Management of Diabetes with Ryzodeg™ Treatment)

  • Jothydev Kesavadev,
  • Ambanna Gowda,
  • Harish Kumar,
  • Sadasiva Rao Yalamanchi,
  • Sailesh Lodha,
  • Kiran Pal Singh,
  • Debasis Basu,
  • Arthur Asirvatham,
  • Navneet Shah and
  • Jagat Jyoti Mukherjee
  • + 2 authors

21 December 2021

This post-authorization study was conducted to evaluate the safety of insulin degludec/insulin aspart (IDegAsp) in adult patients with diabetes mellitus (DM) during routine clinical care under a real-world setting in India. Eligible patients received...

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Med. Sci. - ISSN 2076-3271