A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Data Extraction
2.2. Risk of Bias Assessment
2.3. Statistical Analysis
3. Results
3.1. Study Characteristics
3.2. Death
3.3. Mechanical Ventilation
3.4. ICU Admission
4. Discussion
Limitations of the Study
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Study | Type of Study | Region | CAC Scoring | Events Reported | Newcastle-Ottawa Scale |
---|---|---|---|---|---|
Luo et al. 2021 | Retrospective Cohort | China | V-CACS | Death Mechanical Ventilation ICU Admission | 9 |
Gupta et al. 2021 | Retrospective Cohort | United States | V-CACS | Death Mechanical Ventilation ICU Admission | 9 |
Mousseaux et al. 2021 | Prospective Cohort | France | V-CACS | Death Mechanical Ventilation ICU Admission | 8 |
Fazzari et al. 2021 | Retrospective Cohort | Italy | Agatston | Death Mechanical Ventilation ICU Admission | 9 |
Gianni et al. 2021 | Retrospective Cohort | Italy | Agatston | Death Mechanical Ventilation | 8 |
Dillinger et al. 2020 * | Cross-sectional | France | Agatston | Death Mechanical Ventilation | 8 |
Slipczuk et al. 2021 | Retrospective Cohort | United States | V-CACS | Death | 9 |
Zimmermann et al. 2021 | Retrospective Cohort | Germany | Agatston | Death ICU Admission | 8 |
Study | CAC Severity | Total Patients (N) | Death | ICU Admission | Mechanical Ventilation |
---|---|---|---|---|---|
Luo et al. 2021 | High CAC | 177 | 27 | 37 | 23 |
Low CAC | 1890 | 52 | 91 | 73 | |
Gupta et al. 2021 | Absent | 51 | 8 | -- | 13 |
Mild | 42 | 15 | -- | 15 | |
Moderate | 23 | 8 | -- | 10 | |
Severe | 42 | 19 | -- | 12 | |
Mousseaux et al. 2021 | Absent | 64 | 7 | 21 | 17 |
Mild | 42 | 11 | 17 | 8 | |
Moderate | 26 | 9 | 8 | 4 | |
Heavy | 37 | 17 | 7 | 7 | |
Fazzari et al. 2021 | CAC 0 | 138 | 15 | 31 | 28 |
CAC 1–299 | 94 | 22 | 27 | 25 | |
CAC 300–999 | 34 | 12 | 4 | 4 | |
CAC ≥ 1000 | 16 | 8 | 3 | 3 | |
Gianni et al. 2021 | CAC ≤ 335.48 | 868 | 125 | -- | 136 |
CAC > 335.48 | 225 | 86 | -- | 19 | |
Dillinger et al. 2020 | CAC = 0 | 103 | 2 | -- | 10 |
CAC ≥ 1 | 106 | 7 | -- | 20 | |
Slipczuk et al. 2021 | CAC = 0 | 147 | 50 | -- | -- |
CAC ≥ 1 | 308 | 131 | -- | -- | |
Zimmermann et al. 2021 | CAC = 0 | 40 | 2 | 11 | -- |
CAC ≥ 1 | 69 | 9 | 37 | -- | |
Total | -- | 4542 | 642 | 294 | 427 |
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Lee, K.K.; Rahimi, O.; Lee, C.K.; Shafi, A.; Hawwass, D. A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis. Med. Sci. 2022, 10, 5. https://doi.org/10.3390/medsci10010005
Lee KK, Rahimi O, Lee CK, Shafi A, Hawwass D. A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis. Medical Sciences. 2022; 10(1):5. https://doi.org/10.3390/medsci10010005
Chicago/Turabian StyleLee, Kevin Kyungmin, Osman Rahimi, Charlie Kyungchan Lee, Amaan Shafi, and Dalia Hawwass. 2022. "A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis" Medical Sciences 10, no. 1: 5. https://doi.org/10.3390/medsci10010005
APA StyleLee, K. K., Rahimi, O., Lee, C. K., Shafi, A., & Hawwass, D. (2022). A Meta-Analysis: Coronary Artery Calcium Score and COVID-19 Prognosis. Medical Sciences, 10(1), 5. https://doi.org/10.3390/medsci10010005