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Microorganisms, Volume 11, Issue 5

2023 May - 266 articles

Cover Story: Efficient feed utilization in dairy cows is crucial, both economically and environmentally. In addition to genetics, diets, and management, rumen microbiota play a vital role in feed digestion, yet their precise contribution remains unclear. Machine learning enables the prediction of dairy cows' residual energy intake phenotype based on microbial consortia. Furthermore, the microbiota of efficient animals emphasize distinct metabolic pathways compared to less efficient ones. To comprehensively understand the impact of the rumen microbiome on animal performance, eukaryotes and interkingdom interactions deserve more attention alongside the bacteria and archaea currently in focus. View this paper
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Articles (266)

  • Article
  • Open Access
2 Citations
2,582 Views
14 Pages

Chitinolytic Enzymes of the Hyperparasite Fungus Aphanocladium album: Genome-Wide Survey and Characterization of A Selected Enzyme

  • Claudia Leoni,
  • Caterina Manzari,
  • Matteo Chiara,
  • Pasqua Veronico,
  • Giovanni Luigi Bruno,
  • Graziano Pesole,
  • Luigi R. Ceci and
  • Mariateresa Volpicella

The filamentous fungus Aphanocladium album is known as a hyperparasite of plant pathogenic fungi; hence, it has been studied as a possible agent for plant protection. Chitinases secreted by A. album have proven to be essential for its fungicidal acti...

  • Article
  • Open Access
14 Citations
3,673 Views
15 Pages

Oral Administration of Lactobacillus sakei CVL-001 Improves Recovery from Dextran Sulfate Sodium-Induced Colitis in Mice by Microbiota Modulation

  • Dong-Yeon Kim,
  • Tae-Sung Lee,
  • Do-Hyeon Jung,
  • Eun-Jung Song,
  • Ah-Ra Jang,
  • Ji-Yeon Park,
  • Jae-Hun Ahn,
  • In-Su Seo,
  • Seung-Ju Song and
  • Jong-Hwan Park
  • + 3 authors

Inflammatory bowel disease (IBD) is an intestinal chronic inflammatory disease, and its incidence is steadily increasing. IBD is closely related to the intestinal microbiota, and probiotics are known to be a potential therapeutic agent for IBD. In ou...

  • Article
  • Open Access
3 Citations
2,701 Views
10 Pages

Mycoplasma pneumoniae (Mp) is a common cause of lower respiratory tract infection (LRTI) in children that is difficult to distinguish from LRTI of other etiologies. We aimed to determine if a combination of clinical, laboratory, and chest radiographi...

  • Article
  • Open Access
6 Citations
2,558 Views
29 Pages

This study investigated the effects of dietary commercial feed (n = 50,025 in triplicate, named group PF for soil dike pond, sampling n = 7; n = 15,000 in triplicate, WF for water tank, n = 8), iced fish (n = 50,025 in triplicate, PI, n = 7), and a c...

  • Article
  • Open Access
2 Citations
3,943 Views
14 Pages

Tryptophan is an essential amino acid required for tumor cell growth and is also the precursor to kynurenine, an immunosuppressive molecule that plays a role in limiting anticancer immunity. Tryptophanase (TNase) is an enzyme expressed by different b...

  • Article
  • Open Access
6 Citations
3,289 Views
17 Pages

Structure of Microbial Communities and Biological Activity in Tundra Soils of the Euro-Arctic Region (Rybachy Peninsula, Russia)

  • Maria V. Korneykova,
  • Vladimir A. Myazin,
  • Nadezhda V. Fokina,
  • Alexandra A. Chaporgina,
  • Dmitry A. Nikitin and
  • Andrey V. Dolgikh

The relevance of the Arctic regions’ study is rapidly increasing due to the sensitive response of fragile ecosystems to climate change and anthropogenic pressure. The microbiome is an important component that determines the soils’ functio...

  • Article
  • Open Access
5 Citations
3,093 Views
26 Pages

Synbiotics contain health-beneficial bacteria, i.e., probiotics and prebiotics selectively utilized by the probiotics. Herein, three probiotic strains, Leuconostoc lactis CCK940, L. lactis SBC001, and Weissella cibaria YRK005, and the oligosaccharide...

  • Article
  • Open Access
8 Citations
2,828 Views
10 Pages

Antibiotics Resistance and Adhesive Properties of Clinical Staphylococcus aureus Isolated from Wound Infections

  • Khulood Fahad Alabbosh,
  • Tarek Zmantar,
  • Abdulrahman S. Bazaid,
  • Mejdi Snoussi and
  • Emira Noumi

Staphylococcus aureus (S. aureus) is a ubiquitous pathogen responsible for several severe infections. This study aimed to investigate the adhesive properties and antibiotic resistance among clinical S. aureus isolated from Hail Hospital Province, Kin...

  • Article
  • Open Access
11 Citations
5,321 Views
20 Pages

The main purpose of this study was to degrade total petroleum hydrocarbons (TPHs) from contaminated soil in batch microcosm reactors. Native soil fungi isolated from the same petroleum-polluted soil and ligninolytic fungal strains were screened and a...

  • Communication
  • Open Access
1 Citations
2,155 Views
11 Pages

Total Osteopontin and Its Isoform OPN4 Are Differently Expressed in Respiratory Samples during Influenza A(H1N1)pdm09 Infection and Progression

  • Jéssica Santa Cruz de Carvalho Martins,
  • Thiago das Chagas Sousa,
  • Maria de Lourdes de Aguiar Oliveira,
  • Etel Rodrigues Pereira Gimba,
  • Marilda Mendonça Siqueira and
  • Aline da Rocha Matos

Influenza A virus (IAV) infection affects the human respiratory tract, causing an acute and highly contagious disease. Individuals with comorbidities and in the extremes of age are classified as risk groups for serious clinical outcomes. However, par...

  • Article
  • Open Access
5 Citations
2,594 Views
12 Pages

Investigating the Impacts of UVC Radiation on Natural and Cultured Biofilms: An assessment of Cell Viability

  • Cierra R. Braga,
  • Kailey N. Richard,
  • Harrison Gardner,
  • Geoffrey Swain and
  • Kelli Z. Hunsucker

Biofilms are conglomerates of cells, water, and extracellular polymeric substances which can lead to various functional and financial setbacks. As a result, there has been a drive towards more environmentally friendly antifouling methods, such as the...

  • Article
  • Open Access
8 Citations
2,550 Views
17 Pages

Evaluation of Rouxiella badensis Subsp Acadiensis (Canan SV-53) as a Potential Probiotic Bacterium

  • Ivanna Novotny-Nuñez,
  • Gabriela Perdigón,
  • Chantal Matar,
  • María José Martínez Monteros,
  • Nour Yahfoufi,
  • Silvia Inés Cazorla and
  • Carolina Maldonado-Galdeano

The advent of omic platforms revealed the significant benefits of probiotics in the prevention of many infectious diseases. This led to a growing interest in novel strains of probiotics endowed with health characteristics related to microbiome and im...

  • Article
  • Open Access
11 Citations
3,191 Views
12 Pages

Antiherpetic Activity of Taurisolo®, a Grape Pomace Polyphenolic Extract

  • Carla Zannella,
  • Annalisa Chianese,
  • Giuseppe Annunziata,
  • Annalisa Ambrosino,
  • Anna De Filippis,
  • Gian Carlo Tenore,
  • Ettore Novellino,
  • Mariano Stornaiuolo and
  • Massimiliano Galdiero

Herpes simplex virus (HSV) is widespread in the population, causing oral or genital ulcers and, rarely, severe complications such as encephalitis, keratitis, and neonatal herpes. Current available anti-HSV drugs are acyclovir and its derivatives, alt...

  • Article
  • Open Access
39 Citations
7,876 Views
20 Pages

Study of Antimicrobial Resistance, Biofilm Formation, and Motility of Pseudomonas aeruginosa Derived from Urine Samples

  • Telma de Sousa,
  • Michel Hébraud,
  • Olimpia Alves,
  • Eliana Costa,
  • Luís Maltez,
  • José Eduardo Pereira,
  • Ângela Martins,
  • Gilberto Igrejas and
  • Patricia Poeta

Pseudomonas aeruginosa causes urinary tract infections associated with catheters by forming biofilms on the surface of indwelling catheters. Therefore, controlling the spread of the bacteria is crucial to preventing its transmission in hospitals and...

  • Review
  • Open Access
48 Citations
18,854 Views
34 Pages

Fermented Beverage Benefits: A Comprehensive Review and Comparison of Kombucha and Kefir Microbiome

  • Ann Qi Chong,
  • Siew Wen Lau,
  • Nyuk Ling Chin,
  • Rosnita A. Talib and
  • Roseliza Kadir Basha

Beverage fermentation is an ancient ritual that has been practised for millennia. It was slowly disappearing from households and communities due to the advancement of manufacturing technology and the marketing of soft drinks until the recent revival...

  • Article
  • Open Access
3 Citations
2,232 Views
11 Pages

Localization of C Cycle Enzymes in Arable and Forest Phaeozems within Levels of Soil Microstructure

  • Anna Yudina,
  • Olga Ovchinnikova,
  • Vladimir Cheptsov and
  • Dmitry Fomin

Soil microbial and enzyme activities are closely related to the spatial variability of soil environmental conditions at the microscale (μm-mm). The origin and localization of the enzymes are somewhat neglected when the measured activity is used to...

  • Article
  • Open Access
5 Citations
2,267 Views
15 Pages

Favipiravir Suppresses Zika Virus (ZIKV) through Activity as a Mutagen

  • Evelyn J. Franco,
  • Eleonora Cella,
  • Xun Tao,
  • Kaley C. Hanrahan,
  • Taj Azarian and
  • Ashley N. Brown

In a companion paper, we demonstrated that the nucleoside analogue favipiravir (FAV) suppressed Zika virus (ZIKV) replication in three human-derived cell lines—HeLa, SK-N-MC, and HUH-7. Our results revealed that FAV’s effect was most pron...

  • Article
  • Open Access
10 Citations
3,171 Views
26 Pages

Downy mildew (caused by Plasmopara viticola) and gray mold (caused by Botrytis cinerea) are fungal diseases that significantly impact grape production globally. Cytochrome b plays a significant role in the mitochondrial respiratory chain of the two f...

  • Review
  • Open Access
7 Citations
3,151 Views
11 Pages

Eusocial wasps are represented in the Vespidae by the subfamilies Stenogastrinae, Vespinae and Polistinae. These wasps present colonies that are sometimes composed of thousands of individuals which live in nests built with paper materials. The high d...

  • Review
  • Open Access
51 Citations
11,221 Views
27 Pages

Epizootic Hemorrhagic Disease Virus: Current Knowledge and Emerging Perspectives

  • Luis Jiménez-Cabello,
  • Sergio Utrilla-Trigo,
  • Gema Lorenzo,
  • Javier Ortego and
  • Eva Calvo-Pinilla

Epizootic Hemorrhagic Disease (EHD) of ruminants is a viral pathology that has significant welfare, social, and economic implications. The causative agent, epizootic hemorrhagic disease virus (EHDV), belongs to the Orbivirus genus and leads to signif...

  • Review
  • Open Access
29 Citations
5,965 Views
26 Pages

Inside Current Winemaking Challenges: Exploiting the Potential of Conventional and Unconventional Yeasts

  • Nunzio A. Fazio,
  • Nunziatina Russo,
  • Paola Foti,
  • Alessandra Pino,
  • Cinzia Caggia and
  • Cinzia L. Randazzo

Wine represents a complex matrix in which microbial interactions can strongly impact the quality of the final product. Numerous studies have focused on optimizing microbial approaches for addressing new challenges to enhance quality, typicity, and fo...

  • Article
  • Open Access
13 Citations
3,953 Views
15 Pages

Importance of Pre-Milking Udder Hygiene to Reduce Transfer of Clostridial Spores from Teat Skin to Raw Milk

  • Johanna Burtscher,
  • Tamara Rudavsky,
  • Ulrike Zitz,
  • Viktoria Neubauer and
  • Konrad J. Domig

Butyric acid producing clostridia (BAPC) cause the so-called late-blowing defect, a serious quality problem in semi-hard and hard cheeses. Late-blown cheeses are characterized by undesired slits and cracks, irregular eyes, and off-flavors due to exce...

  • Article
  • Open Access
2 Citations
4,418 Views
12 Pages

Several strains of a Gram-negative, anaerobic photoautotrophic, motile, rod-shaped bacterium, designated as B14B, A-7R, and A-7Y were isolated from biofilms of low-mineralized soda lakes in central Mongolia and Russia (southeast Siberia). They had la...

  • Review
  • Open Access
47 Citations
10,628 Views
34 Pages

Viability of Probiotic Microorganisms and the Effect of Their Addition to Fruit and Vegetable Juices

  • Maria Spinasse Maia,
  • Manueli Monciozo Domingos and
  • Jackline Freitas Brilhante de São José

Consumers’ recent interest in healthier diets has increased the demand for food products with functional properties, such as probiotics. However, most probiotic food types available on the market are of dairy origin, which limits their consumpt...

  • Review
  • Open Access
13 Citations
5,858 Views
19 Pages

The effect of the intestinal microbiome on the gut–brain axis has received considerable attention, strengthening the evidence that intestinal bacteria influence emotions and behavior. The colonic microbiome is important to health and the patter...

  • Article
  • Open Access
19 Citations
3,482 Views
12 Pages

We describe the impact of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic on invasive pneumococcal disease (IPD) in Calgary. IPD declined significantly worldwide during 2020 and 2021. This may be due to the reduced transmission o...

  • Article
  • Open Access
1 Citations
3,076 Views
12 Pages

Phenotypic Variation in Clinical S. aureus Isolates Did Not Affect Disinfection Efficacy Using Short-Term UV-C Radiation

  • Birte Knobling,
  • Gefion Franke,
  • Laura Carlsen,
  • Cristina Belmar Campos,
  • Henning Büttner,
  • Eva M. Klupp,
  • Philipp Maximilian Maurer and
  • Johannes K. Knobloch

Pigmentation, catalase activity and biofilm formation are virulence factors that cause resistance of Staphylococcus aureus to environmental stress factors including disinfectants. In recent years, automatic UV-C room disinfection gained greater impor...

  • Article
  • Open Access
4 Citations
2,729 Views
17 Pages

Klebsiella aerogenes Adhesion Behaviour during Biofilm Formation on Monazite

  • Arya Van Alin,
  • Melissa K. Corbett,
  • Homayoun Fathollahzadeh,
  • M. Christian Tjiam,
  • Andrew Putnis,
  • Jacques Eksteen,
  • Anna H. Kaksonen and
  • Elizabeth Watkin

The adsorption behaviour of micro-organisms during the initial attachment stage of biofilm formation affects subsequent stages. The available area for attachment and the chemophysical properties of a surface affect microbial attachment performance. T...

  • Article
  • Open Access
4 Citations
2,651 Views
11 Pages

Antibiotic resistance is a significant and pressing issue in the medical field, as numerous strains of infectious bacteria have become resistant to commonly prescribed antibiotics. Staphylococcus aureus is a bacterium that poses a grave threat, as it...

  • Article
  • Open Access
3 Citations
3,268 Views
27 Pages

Comprehensive Approaches for the Search and Characterization of Staphylococcins

  • Rosa Fernández-Fernández,
  • Carmen Lozano,
  • Rine Christopher Reuben,
  • Laura Ruiz-Ripa,
  • Myriam Zarazaga and
  • Carmen Torres

Novel and sustainable approaches are required to curb the increasing threat of antimicrobial resistance (AMR). Within the last decades, antimicrobial peptides, especially bacteriocins, have received increased attention and are being explored as suita...

  • Review
  • Open Access
8 Citations
3,191 Views
14 Pages

Microbial Interventions to Improve Neonatal Gut Health

  • Ranga Nakandalage,
  • Le Luo Guan and
  • Nilusha Malmuthuge

The diverse pioneer microbial community colonizing the mammalian gastrointestinal tract is critical for the developing immune system. Gut microbial communities of neonates can be affected by various internal and external factors, resulting in microbi...

  • Article
  • Open Access
1 Citations
2,284 Views
14 Pages

Colorectal cancer (CRC) develops from pre-cancerous cellular lesions in the gut epithelium and mainly originates from specific types of colonic adenomas with dysplasia. However, gut microbiota signatures among sampling sites in patients with colorect...

  • Article
  • Open Access
9 Citations
2,861 Views
13 Pages

Quorum sensing inhibitors (QSIs) are an attractive alternative to antibiotic growth promoters in farmed animal nutrition. The goal of the study was the diet supplementation of Arbor Acres chickens with quercetin (QC), vanillin (VN), and umbelliferon...

  • Communication
  • Open Access
5 Citations
2,929 Views
12 Pages

Unveiling the Emergence and Genetic Diversity of OXA-48-like Carbapenemase Variants in Shewanella xiamenensis

  • Xueqi Jiang,
  • Beibei Miao,
  • Xiaofei Zhao,
  • Xuemei Bai,
  • Min Yuan,
  • Xia Chen,
  • Xinyi Gong,
  • Zeliang Liu,
  • Jie Li and
  • Juan Li
  • + 2 authors

An increase in the carbapenem-hydrolyzing capacity of class D β-lactamase has been observed in strains of multiple species, posing a significant challenge to the control of antibiotic resistance. In this study, we aimed to investigate the geneti...

  • Article
  • Open Access
16 Citations
4,694 Views
18 Pages

In Vitro Effect of the Cell-Free Supernatant of the Lactobacillus casei Strain IMAU60214 against the Different Pathogenic Properties of Diarrheagenic Escherichia coli

  • Luz María Rocha-Ramírez,
  • Ulises Hernández-Chiñas,
  • Silvia Selene Moreno-Guerrero,
  • Arturo Ramírez-Pacheco and
  • Carlos A. Eslava

Enteroaggregative Escherichia coli (EAEC) and enterohemorrhagic E. coli (EHEC) are E. coli pathotypes associated with unmanageable diarrhea in children and adults. An alternative to the treatment of infections caused by these microorganisms is the us...

  • Review
  • Open Access
21 Citations
10,963 Views
15 Pages

The Fight against Poliovirus Is Not Over

  • Chaldam Jespère Mbani,
  • Magloire Pandoua Nekoua,
  • Donatien Moukassa and
  • Didier Hober

Poliovirus (PV), the virus that causes both acute poliomyelitis and post-polio syndrome, is classified within the Enterovirus C species, and there are three wild PV serotypes: WPV1, WPV2 and WPV3. The launch of the Global Polio Eradication Initiative...

  • Article
  • Open Access
2 Citations
2,311 Views
17 Pages

Leishmaniasis is a protozoan disease responsible for significant morbidity and mortality. There is no recommended vaccine to protect against infection. In this study, transgenic Leishmania tarentolae expressing gamma glutamyl cysteine synthetase (&ga...

  • Article
  • Open Access
8 Citations
3,392 Views
14 Pages

Genetic Engineering of Klebsiella pneumoniae ATCC 25955 for Bioconjugate Vaccine Applications

  • Yan Liu,
  • Shulei Li,
  • Yan Guo,
  • Xin Li,
  • Li Zhu,
  • Hengliang Wang,
  • Jun Wu and
  • Chao Pan

Vaccination is considered the most effective means to fight against the multidrug-resistant strains of Klebsiella pneumoniae. In recent years, a potential protein glycan coupling technology has been extensively used in the production of bioconjugated...

  • Article
  • Open Access
29 Citations
5,045 Views
11 Pages

16S-23S rRNA Internal Transcribed Spacer Region (ITS) Sequencing: A Potential Molecular Diagnostic Tool for Differentiating Lactococcus garvieae and Lactococcus petauri

  • Nadia Stoppani,
  • Silvia Colussi,
  • Paolo Pastorino,
  • Marino Prearo,
  • Simona Sciuto,
  • Ilhan Altinok,
  • Rafet Çağrı Öztürk,
  • Mustafa Ture,
  • Ana Isabel Vela and
  • Jose Francisco Fernández-Garayzábal
  • + 7 authors

Lactococcus garvieae is the etiological agent of lactococcosis, a clinically and economically significant infectious disease affecting farmed rainbow trout. L. garvieae had been considered the only cause of lactococcosis for a long time; however, L. ...

  • Article
  • Open Access
8 Citations
3,351 Views
17 Pages

Klebsiella pneumoniae, a member of the Enterobacteriaceae family, has become a dangerous pathogen accountable for a large fraction of the various infectious diseases in both clinical and community settings. In general, the K. pneumoniae population ha...

  • Review
  • Open Access
8 Citations
5,153 Views
18 Pages

Due to the global crisis caused by the dramatic rise of drug resistance among Gram-negative bacteria, there is an urgent need for a thorough understanding of the pathogenesis of infections of such an etiology. In light of the limited availability of...

  • Article
  • Open Access
11 Citations
3,256 Views
18 Pages

Integrated Microbiota and Metabolome Analysis to Assess the Effects of the Solid-State Fermentation of Corn–Soybean Meal Feed Using Compound Strains

  • Yue Li,
  • Qinghong Hao,
  • Chunhui Duan,
  • Yawei Ding,
  • Yuanyuan Wang,
  • Xiaojun Guo,
  • Yueqin Liu,
  • Yunxia Guo and
  • Yingjie Zhang

Solid-state fermentation is known to improve plant-based feed nutritional quality; however, the association between microbes and metabolite production in fermented feed remains unclear. We inoculated corn–soybean–wheat bran (CSW) meal fee...

  • Article
  • Open Access
5 Citations
3,313 Views
26 Pages

Bacterial Microbiota of Ostreobium, the Coral-Isolated Chlorophyte Ectosymbiont, at Contrasted Salinities

  • Anaïs Massé,
  • Juliette Detang,
  • Charlotte Duval,
  • Sébastien Duperron,
  • Anthony C. Woo and
  • Isabelle Domart-Coulon

Microscopic filaments of the siphonous green algae Ostreobium (Ulvophyceae, Bryopsidales) colonize and dissolve the calcium carbonate skeletons of coral colonies in reefs of contrasted salinities. Here, we analyzed their bacterial community’s c...

  • Review
  • Open Access
25 Citations
5,487 Views
15 Pages

Undigested dietary and endogenous proteins, as well as unabsorbed amino acids, can move from the terminal part of the ileum into the large intestine, where they meet a dense microbial population. Exfoliated cells and mucus released from the large int...

  • Article
  • Open Access
2 Citations
2,562 Views
16 Pages

Carbapenem-Resistant Pseudomonas aeruginosa Bacteremia, through a Six-Year Infection Control Program in a Hospital

  • Amalia Papanikolopoulou,
  • Panagiotis Gargalianos-Kakolyris,
  • Athina Stoupis,
  • Nikos Moussas,
  • Anastasia Pangalis,
  • Kalliopi Theodoridou,
  • Genovefa Chronopoulou,
  • Nikos Pantazis,
  • Maria Kantzanou and
  • Athanasios Tsakris
  • + 1 author

Background: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a life-threatening healthcare-associated infection affecting especially patients with immunosuppression and comorbidities. We investigated the association between the incidence of CRPA...

  • Review
  • Open Access
114 Citations
14,192 Views
21 Pages

Gastric cancer is a challenging public health concern worldwide and remains a leading cause of cancer-related mortality. The primary risk factor implicated in gastric cancer development is infection with Helicobacter pylori. H. pylori induces chronic...

  • Article
  • Open Access
2 Citations
2,286 Views
13 Pages

Comparison of the Diagnostic Accuracy of Three Real-Time PCR Assays for the Detection of Arcobacter butzleri in Human Stool Samples Targeting Different Genes in a Test Comparison without a Reference Standard

  • Ramona Binder,
  • Andreas Hahn,
  • Kirsten Alexandra Eberhardt,
  • Ralf Matthias Hagen,
  • Holger Rohde,
  • Ulrike Loderstädt,
  • Torsten Feldt,
  • Fred Stephen Sarfo,
  • Veronica Di Cristanziano and
  • Andreas Erich Zautner
  • + 2 authors

Potential etiological relevance for gastroenteric disorders including diarrhea has been assigned to Arcobacter butzleri. However, standard routine diagnostic algorithms for stool samples of patients with diarrhea are rarely adapted to the detection o...

  • Article
  • Open Access
3 Citations
3,324 Views
21 Pages

Bovine udder health is an important factor for animal wellbeing and the dairy farm economy. Thus, researchers aim to understand factors causing mastitis. The gold standard for diagnosing mastitis in cows is the conventional culturing of milk samples....

  • Article
  • Open Access
8 Citations
2,988 Views
15 Pages

Expression of Envelope Protein Encoded by Endogenous Retrovirus K102 in Rheumatoid Arthritis Neutrophils

  • Amanda Laine,
  • Xiaoxing Wang,
  • Kathryn Ni,
  • Sarah E. B. Smith,
  • Rayan Najjar,
  • Leanne S. Whitmore,
  • Michael Yacoub,
  • Alison Bays,
  • Michael Gale and
  • Tomas Mustelin

Many patients suffering from autoimmune diseases have autoantibodies against proteins encoded by genomic retroelements, suggesting that normal epigenetic silencing is insufficient to prevent the production of the encoded proteins for which immune tol...

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Microorganisms - ISSN 2076-2607