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Pathogens, Volume 13, Issue 7

July 2024 - 85 articles

Cover Story: Tolerance enables bacteria to survive intermittent antibiotic exposure without an increase in antimicrobial susceptibility. In this study, we investigated the presence of tolerance to three antimicrobials, ceftriaxone, azithromycin and ciprofloxacin in clinical isolates of Neisseria gonorrhoeae. A total of 4 of the 62 clinical anorectal isolates and none of the urogenital isolates exhibited tolerance to azithromycin. Tolerance to ceftriaxone and ciprofloxacin was observed in eight and four isolates, respectively, with no difference between infection sites. Tolerance was also detected in 8 (K, M, N, O, P, U, V, W) out of the 14 WHO reference strains. This study identified ceftriaxone, azithromycin and ciprofloxacin tolerance in clinical and WHO reference N. gonorrhoeae isolates. Azithromycin tolerance was more common in anorectal than urogenital infections. View this paper
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Articles (85)

  • Review
  • Open Access
8 Citations
4,273 Views
22 Pages

A Comparative Assessment of the Pathogenic Potential of Newly Discovered Henipaviruses

  • Kristina Meier,
  • Judith Olejnik,
  • Adam J. Hume and
  • Elke Mühlberger

Recent advances in high-throughput sequencing technologies have led to the discovery of a plethora of previously unknown viruses in animal samples. Some of these newly detected viruses are closely related to human pathogens. A prime example are the h...

  • Article
  • Open Access
3 Citations
2,093 Views
15 Pages

The Impact of Altitude on Tick-Borne Pathogens at Two Mountain Ranges in Central Slovakia

  • Dana Zubriková,
  • Lucia Blaňarová,
  • Gabriela Hrkľová,
  • Yaroslav Syrota,
  • Jozef Macko,
  • Dana Blahútová,
  • Veronika Blažeková,
  • Michal Stanko,
  • Klaudia Švirlochová and
  • Bronislava Víchová

Ticks are ectoparasites of a wide range of animals and are important vectors of numerous pathogens affecting humans, livestock, and pets. This study investigates possible correlations between selected factors, altitude, soil pH, and a factor called &...

  • Article
  • Open Access
3 Citations
2,687 Views
16 Pages

Uncovering the Antifungal Potential of Plant-Associated Cultivable Bacteria from the Aral Sea Region against Phytopathogenic Fungi

  • Ilkham S. Aytenov,
  • Tohir A. Bozorov,
  • Daoyuan Zhang,
  • Sitora A. Samadiy,
  • Dono A. Muhammadova,
  • Marufbek Z. Isokulov,
  • Sojida M. Murodova,
  • Ozoda R. Zakirova,
  • Bakhodir Kh. Chinikulov and
  • Anvar G. Sherimbetov

Two freshwater rivers, the Amu Darya and Syr Darya, flow into the Aral Sea, but they began to diminish in the early 1960s, and by the 1980s, the lake had nearly ceased to exist due to excessive water consumption for agriculture and the unsustainable...

  • Brief Report
  • Open Access
1 Citations
2,311 Views
10 Pages

The Genomic Epidemiology of Clinical Burkholderia pseudomallei Isolates in North Queensland, Australia

  • Ian Gassiep,
  • Mark D. Chatfield,
  • Budi Permana,
  • Delaney Burnard,
  • Michelle J. Bauer,
  • Thom Cuddihy,
  • Brian M. Forde,
  • Johanna Mayer-Coverdale,
  • Robert E. Norton and
  • Patrick N. A. Harris

Background: Burkholderia pseudomallei, the causative agent of melioidosis, is highly genetically recombinant, resulting in significant genomic diversity. Multiple virulence factors have been associated with specific disease presentations. To dat...

  • Article
  • Open Access
5 Citations
2,037 Views
18 Pages

Clustering of Gastrointestinal Microorganisms in Human Stool Samples from Ghana

  • Joy Backhaus,
  • Simone Kann,
  • Andreas Hahn,
  • Felix Weinreich,
  • Martin Blohm,
  • Konstantin Tanida,
  • Torsten Feldt,
  • Fred Stephen Sarfo,
  • Veronica Di Cristanziano and
  • Ulrike Loderstädt
  • + 5 authors

The study was conducted to identify cluster patterns of enteric microorganisms with potential etiological relevance for infectious gastroenteritis in stool samples of individuals from Ghana, which is a known high-endemicity setting for infectious gas...

  • Article
  • Open Access
1 Citations
2,181 Views
12 Pages

Monoclonal Antibodies for Rift Valley Fever Virus Nucleocapsid: Application in IgG/IgM ELISA for Sero-Diagnosis

  • Jiansheng Huang,
  • Ferdinard Adungo,
  • Samson Limbaso Konongoi,
  • Shingo Inoue,
  • Lin Zhan,
  • Rosemary Sang,
  • Salame Ashur,
  • Allan ole Kwallah,
  • Matilu Mwau and
  • Kouichi Morita
  • + 1 author

Introduction: Rift Valley fever virus (RVFV) belonging to the Phenuiviridae family is responsible for a zoonotic disease called Rift Valley fever (RVF). Currently, RVFV has spread from Africa to Asia, and due to its ability to cause high mortality ra...

  • Article
  • Open Access
4 Citations
1,777 Views
12 Pages

Genetic Homogeneity of Francisella tularensis subsp. mediasiatica Strains in Kazakhstan

  • Alexandr Shevtsov,
  • Uinkul Izbanova,
  • Asylulan Amirgazin,
  • Alma Kairzhanova,
  • Ayan Dauletov,
  • Vladimir Kiyan and
  • Gilles Vergnaud

Tularemia is an acute febrile disease caused by the Gram-negative bacillus Francisella tularensis. Based on genetic and phenotypic characteristics, three subspecies are distinguished: tularensis, holarctica, and mediasiatica. F. tularensis subsp. med...

  • Review
  • Open Access
3 Citations
5,276 Views
19 Pages

Grade C molar-incisor pattern periodontitis (C-MIP) is a disease that affects specific teeth with an early onset and aggressive progression. It occurs in systemically healthy patients, mostly African descendants, at an early age, with familial involv...

  • Article
  • Open Access
7 Citations
1,806 Views
15 Pages

Native Biocrust Cyanobacteria Strains Showing Antagonism against Three Soilborne Pathogenic Fungi

  • Pilar Águila-Carricondo,
  • Raúl Román,
  • José Ignacio Marín-Guirao,
  • Yolanda Cantón and
  • Miguel de Cara

The biocontrol potential of three native soil cyanobacteria from biological soil crusts (Nostoc commune, Scytonema hyalinum, and Tolypothrix distorta) was tested by means of in vitro mycelial growth inhibition assays for eighteen cyanobacteria-based...

  • Article
  • Open Access
1,785 Views
13 Pages

Plasma Photoinactivation of Bacterial Isolated from Blood Donors Skin: Potential of Security Barrier in Transfusional Therapy

  • Yanet Ventura-Enríquez,
  • Antonio Casas-Guerrero,
  • María de Jesús Sánchez-Guzmán,
  • Miguel Ángel Loyola-Cruz,
  • Clemente Cruz-Cruz,
  • Andres Emmanuel Nolasco-Rojas,
  • Emilio Mariano Durán-Manuel,
  • Dulce Milagros Razo Blanco-Hernández,
  • Francisco Álvarez-Mora and
  • Gabriela Ibáñez-Cervantes
  • + 3 authors

The presence of skin bacteria capable of forming biofilm, exhibiting antibiotic resistance, and displaying virulence represents a significant challenge in the field of transfusion medicine. This underscores the necessity of enhancing the microbiologi...

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Pathogens - ISSN 2076-0817