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Pathogens, Volume 12, Issue 3

March 2023 - 150 articles

Cover Story: Protein synthesis is a central process in all cells, and its regulation plays a key role in bacteria–host interactions. One of the important aspects of protein synthesis is limiting errors and maintaining translational fidelity. In this review, we summarize recent findings on how translational fidelity in bacteria is altered by genetic and environmental cues and, in turn, affects stress adaptations and host interactions. We also point out some future directions to understand the role of translational fidelity in the pathogenesis of various bacterial species, an emerging area in studying bacteria–pathogen interactions. View this paper
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Articles (150)

  • Article
  • Open Access
5 Citations
3,090 Views
17 Pages

Spherical Body Protein 4 from Babesia bigemina: A Novel Gene That Contains Conserved B-Cell Epitopes and Induces Cross-Reactive Neutralizing Antibodies in Babesia ovata

  • Juan Mosqueda,
  • Diego Josimar Hernandez-Silva,
  • Massaro W. Ueti,
  • Adolfo Cruz-Reséndiz,
  • Ricardo Marquez-Cervantez,
  • Uriel Mauricio Valdez-Espinoza,
  • Minh-Anh Dang-Trinh,
  • Thu-Thuy Nguyen,
  • Minerva Camacho-Nuez and
  • Miguel Angel Mercado-Uriostegui
  • + 5 authors

Bovine babesiosis is a tick-transmitted disease caused by intraerythrocytic protozoan parasites of the genus Babesia. Its main causative agents in the Americas are Babesia bigemina and Babesia bovis, while Babesia ovata affects cattle in Asia. All Ba...

  • Article
  • Open Access
2 Citations
4,239 Views
15 Pages

Optimized High Throughput Ascochyta Blight Screening Protocols and Immunity to A. pisi in Pea

  • Emmanuel N. Annan,
  • Bernard Nyamesorto,
  • Qing Yan,
  • Kevin McPhee and
  • Li Huang

Ascochyta blight (AB) is a destructive disease of the field pea (Pisum sativum L.) caused by necrotrophic fungal pathogens known as the AB-disease complex. To identify resistant individuals to assist AB resistance breeding, low-cost, high throughput,...

  • Review
  • Open Access
8 Citations
3,873 Views
12 Pages

Slowly progressive spastic paraparesis with bladder dysfunction, the main clinical feature of human T-cell leukemia virus-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP), is induced by chronic inflammation in the spinal cord,...

  • Article
  • Open Access
10 Citations
4,275 Views
13 Pages

Serotypes and Antibiotic Resistance of Streptococcus pneumoniae before and after the Introduction of the 13-Valent Pneumococcal Conjugate Vaccine for Adults and Children in a Rural Area in Japan

  • Takashi Ono,
  • Masahiro Watanabe,
  • Koichi Hashimoto,
  • Yohei Kume,
  • Mina Chishiki,
  • Hisao Okabe,
  • Masatoki Sato,
  • Sakurako Norito,
  • Bin Chang and
  • Mitsuaki Hosoya

The increase in non-vaccine serotypes of Streptococcus pneumoniae and their multidrug resistance have become an issue following the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13). In this study, we investigated the serotypes and...

  • Article
  • Open Access
2 Citations
3,301 Views
11 Pages

Monitoring the Status of Soil-Transmitted Helminthiases in Non-Endemic Implementation Units: A Case Study of Borgu in Northcentral Nigeria

  • Babatunde Adewale,
  • Hammed Mogaji,
  • Joshua Balogun,
  • Emmanuel Balogun,
  • Francisca Olamiju and
  • De’Broski Herbert

Nigeria remains the most endemic country in sub-Saharan Africa (SSA) for soil-transmitted helminthiases (STH). In line with ongoing monitoring plans, we present findings from a recent analysis of STH epidemiological data in Borgu, one of the non-ende...

  • Article
  • Open Access
8 Citations
2,567 Views
12 Pages

Persistence of Tembusu Virus in Culex tritaeniorhynchus in Yunnan Province, China

  • Danhe Hu,
  • Chao Wu,
  • Ruichen Wang,
  • Xiaohui Yao,
  • Kai Nie,
  • Quan Lv,
  • Shihong Fu,
  • Qikai Yin,
  • Wenzhe Su and
  • Fan Li
  • + 5 authors

The Tembusu virus (TMUV), a member of the Flaviviridae family, can be transmitted via mosquitoes and cause poultry disease. In 2020, a strain of TMUV (YN2020-20) was isolated from mosquito samples collected in Yunnan province, China. In vitro experim...

  • Article
  • Open Access
8 Citations
3,364 Views
22 Pages

Attenuation of In Vitro and In Vivo Virulence Is Associated with Repression of Gene Expression of AIG1 Gene in Entamoeba histolytica

  • Janeth Lozano-Mendoza,
  • Fátima Ramírez-Montiel,
  • Ángeles Rangel-Serrano,
  • Itzel Páramo-Pérez,
  • Claudia Leticia Mendoza-Macías,
  • Faridi Saavedra-Salazar,
  • Bernardo Franco,
  • Naurú Vargas-Maya,
  • Ghulam Jeelani and
  • Yumiko Saito-Nakano
  • + 3 authors

Entamoeba histolytica virulence results from complex host–parasite interactions implicating multiple amoebic components (e.g., Gal/GalNAc lectin, cysteine proteinases, and amoebapores) and host factors (microbiota and immune response). UG10 is...

  • Article
  • Open Access
1 Citations
2,651 Views
13 Pages

The Microbial Genetic Diversity and Succession Associated with Processing Waters at Different Broiler Processing Stages in an Abattoir in Australia

  • Josphat Njenga Gichure,
  • Ranil Coorey,
  • Patrick Murigu Kamau Njage,
  • Gary A. Dykes,
  • Esther K. Muema and
  • Elna M. Buys

The high organic content of abattoir-associated process water provides an alternative for low-cost and non-invasive sample collection. This study investigated the association of microbial diversity from an abattoir processing environment with that of...

  • Review
  • Open Access
6 Citations
2,663 Views
13 Pages

Giardia, Cryptosporidium, Cyclospora, and microsporidia are gastrointestinal pathogens that can cause various disease symptoms in both animals and humans. Numerous studies worldwide have confirmed the presence of these eukaryotic pathogens in nesting...

  • Review
  • Open Access
15 Citations
4,248 Views
15 Pages

Breast cancer is the leading cause of death among women worldwide, and certain subtypes are highly aggressive and drug resistant. As oxidative stress is linked to the onset and progression of cancer, new alternative therapies, based on plant-derived...

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Pathogens - ISSN 2076-0817