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Article

CCEO-DCABNet: Chronological Chaotic Evolution Optimization-Enabled Hybrid Deep Learning for Multiclass Disease Classification Using Chest X-Ray Images in Federated Learning

1
Bharati Vidyapeeth (Deemed to be) University, College of Engineering, Pune 411043, India
2
Department of Computer Science and Engineering, Walchand College of Engineering, Sangli 416415, India
3
Department of Civil, Environmental and Mechanical Engineering, University of Trento, 38123 Trento, Italy
4
Department of Information Technology, Bharati Vidyapeeth’s College of Engineering, New Delhi 110063, India
5
INTI International University, Persiaran Perdana BBN Putra Nilai, Nilai 71800, Negeri Sembilan, Malaysia
*
Authors to whom correspondence should be addressed.
Diagnostics 2026, 16(13), 2096; https://doi.org/10.3390/diagnostics16132096
Submission received: 6 May 2026 / Revised: 18 June 2026 / Accepted: 25 June 2026 / Published: 3 July 2026
(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Abstract

Background: Chest X-ray imaging is a widely used diagnostic modality for identifying various lung diseases. Accurate multiclass classification of lung diseases enables timely treatment and improves patient survival. However, disease detection using chest X-ray images remains challenging due to heterogeneous data, overlapping radiographic features, and data privacy concerns. Furthermore, distinguishing among different lung diseases is difficult because of their similar clinical manifestations and imaging characteristics. Method: To address these challenges, a novel chaotic evolution optimization-enabled deep channel-attention broad convolutional neural network (CCEO-DCABNet) is proposed for multiclass lung disease classification within a federated learning (FL) framework. The proposed model ensures enhanced data privacy by allowing multiple client nodes and a central server to collaboratively train the model without sharing raw data. Prior to classification, image preprocessing is performed using Gaussian filter-based denoising followed by multiscale unsharp masking-based image sharpening. Subsequently, multiclass disease classification is carried out using DCABNet, whose parameters are optimized through the proposed CCEO algorithm. In addition, the federated learning process employs an averaging strategy for local model updates and global aggregation. Results: The proposed CCEO-DCABNet achieves an accuracy, true positive rate (TPR), and true negative rate (TNR) of 96.98%, 96.41%, and 97.45%. Conclusions: Experimental results demonstrate that the proposed CCEO-DCABNet framework effectively classifies multiple lung diseases from chest X-ray images while preserving data privacy through federated learning. The model achieves superior classification performance and can support reliable computer-aided diagnosis in clinical settings.
Keywords: chest X-ray image; federated learning; MMPU-Net; Gaussian filter; chaotic evolution optimization chest X-ray image; federated learning; MMPU-Net; Gaussian filter; chaotic evolution optimization

Share and Cite

MDPI and ACS Style

Patil, L.; Garg, B.; Donelli, M.; Jain, A. CCEO-DCABNet: Chronological Chaotic Evolution Optimization-Enabled Hybrid Deep Learning for Multiclass Disease Classification Using Chest X-Ray Images in Federated Learning. Diagnostics 2026, 16, 2096. https://doi.org/10.3390/diagnostics16132096

AMA Style

Patil L, Garg B, Donelli M, Jain A. CCEO-DCABNet: Chronological Chaotic Evolution Optimization-Enabled Hybrid Deep Learning for Multiclass Disease Classification Using Chest X-Ray Images in Federated Learning. Diagnostics. 2026; 16(13):2096. https://doi.org/10.3390/diagnostics16132096

Chicago/Turabian Style

Patil, Leena, Bindu Garg, Massimo Donelli, and Achin Jain. 2026. "CCEO-DCABNet: Chronological Chaotic Evolution Optimization-Enabled Hybrid Deep Learning for Multiclass Disease Classification Using Chest X-Ray Images in Federated Learning" Diagnostics 16, no. 13: 2096. https://doi.org/10.3390/diagnostics16132096

APA Style

Patil, L., Garg, B., Donelli, M., & Jain, A. (2026). CCEO-DCABNet: Chronological Chaotic Evolution Optimization-Enabled Hybrid Deep Learning for Multiclass Disease Classification Using Chest X-Ray Images in Federated Learning. Diagnostics, 16(13), 2096. https://doi.org/10.3390/diagnostics16132096

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