You are currently viewing a new version of our website. To view the old version click .

Genes, Volume 12, Issue 10

October 2021 - 187 articles

Cover Story: Major Depressive Disorder (MDD) is a neuropsychiatric condition with strong ties to disease and lifestyle factors. Trait associations at the population level can result from a shared genetic or environmental etiology. In a twin pedigree approach with almost 20.000 relatives, we establish to what degree genetic and environmental factors influence the association between MDD and smoking behavior, physical inactivity, and obesity. We show that each of these traits is heritable, and that the associations between MDD and lifestyle factors are mainly driven by shared genetic factors.View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (187)

  • Article
  • Open Access
2 Citations
3,406 Views
20 Pages

Novel Candidate Genes Differentially Expressed in Glyphosate-Treated Horseweed (Conyza canadensis)

  • Yongil Yang,
  • Cory Gardner,
  • Pallavi Gupta,
  • Yanhui Peng,
  • Cristiano Piasecki,
  • Reginald J. Millwood,
  • Tae-Hyuk Ahn and
  • C. Neal Stewart

14 October 2021

The evolution of herbicide-resistant weed species is a serious threat for weed control. Therefore, we need an improved understanding of how gene regulation confers herbicide resistance in order to slow the evolution of resistance. The present study a...

  • Case Report
  • Open Access
10 Citations
2,499 Views
9 Pages

A Two-Year Clinical Description of a Patient with a Rare Type of Low-GGT Cholestasis Caused by a Novel Variant of USP53

  • Olga Shatokhina,
  • Natalia Semenova,
  • Nina Demina,
  • Elena Dadali,
  • Alexander Polyakov and
  • Oxana Ryzhkova

14 October 2021

Here, we report a novel truncating mutation in the ubiquitin-specific peptidase gene (USP53) causing low-γ-GT (GGT) cholestasis. Genetic testing was carried out, including clinical exome sequencing for the proband and Sanger sequencing for the proban...

  • Article
  • Open Access
6 Citations
4,391 Views
25 Pages

More Than a Moggy; A Population Genetics Analysis of the United Kingdom’s Non-Pedigree Cats

  • Jennifer Irving McGrath,
  • Wengang Zhang,
  • Regina Hollar,
  • Alison Collings,
  • Roger Powell,
  • Rob D. Foale,
  • Nicola Thurley,
  • Jeffrey A. Brockman,
  • Richard J. Mellanby and
  • Danièlle A. Gunn-Moore
  • + 1 author

14 October 2021

The domestic cat is one of the most popular pets in the world. It is estimated that 89–92% of domestic cats in the UK are non-pedigree Domestic shorthair (DSH), Domestic longhair (DLH), or Domestic semi-longhair cats (DSLH). Despite their popularity,...

  • Review
  • Open Access
43 Citations
4,872 Views
16 Pages

14 October 2021

Plant growth and development and interactions with the environment are regulated by phytohormones and other signaling molecules. During their evolution, plants have developed strategies for efficient signal perception and for the activation of signal...

  • Article
  • Open Access
5 Citations
3,566 Views
10 Pages

Detection of Spinal Muscular Atrophy Patients Using Dried Saliva Spots

  • Yogik Onky Silvana Wijaya,
  • Hisahide Nishio,
  • Emma Tabe Eko Niba,
  • Kentaro Okamoto,
  • Haruo Shintaku,
  • Yasuhiro Takeshima,
  • Toshio Saito,
  • Masakazu Shinohara and
  • Hiroyuki Awano

14 October 2021

Spinal muscular atrophy (SMA) is a lower motor neuron disease, once considered incurable. The main symptoms are muscle weakness and muscular atrophy. More than 90% of cases of SMA are caused by homozygous deletion of survival motor neuron 1 (SMN1). E...

  • Article
  • Open Access
3 Citations
2,464 Views
10 Pages

14 October 2021

The risk factors for stroke, a fatal disease, include type two diabetes, hypertension, and genetic influences. Small vessel occlusion (SVO) can be affected by epigenetic alterations, but an association between SVO and the methylation of cytochrome P4...

  • Article
  • Open Access
5 Citations
3,981 Views
16 Pages

An Investigation of the Role of Common and Rare Variants in a Large Italian Multiplex Family of Multiple Sclerosis Patients

  • Nadia Barizzone,
  • Rachele Cagliani,
  • Chiara Basagni,
  • Ferdinando Clarelli,
  • Laura Mendozzi,
  • Cristina Agliardi,
  • Diego Forni,
  • Martina Tosi,
  • Elisabetta Mascia and
  • Francesco Favero
  • + 17 authors

13 October 2021

Known multiple sclerosis (MS) susceptibility variants can only explain half of the disease’s estimated heritability, whereas low-frequency and rare variants may partly account for the missing heritability. Thus, here we sought to determine the occurr...

  • Review
  • Open Access
14 Citations
5,986 Views
28 Pages

Association and Genetic Expression between Genes Involved in HPA Axis and Suicide Behavior: A Systematic Review

  • Yazmín Hernández-Díaz,
  • Alma Delia Genis-Mendoza,
  • Thelma Beatriz González-Castro,
  • Carlos Alfonso Tovilla-Zárate,
  • Isela Esther Juárez-Rojop,
  • María Lilia López-Narváez and
  • Humberto Nicolini

13 October 2021

Background: Suicide behavior (SB) has been highly associated with the response to stress and the hypothalamic–pituitary–adrenal (HPA) axis. The aim of this study was to summarize the results obtained in genetic studies that analyzed the HPA axis—stre...

  • Article
  • Open Access
13 Citations
3,772 Views
15 Pages

13 October 2021

Anaerobic archaeal methanogens are key players in the global carbon cycle due to their role in the final stages of organic matter decomposition in anaerobic environments such as wetland sediments. Here we present the first draft metagenome-assembled...

  • Article
  • Open Access
10 Citations
3,026 Views
17 Pages

13 October 2021

Solenopsis japonica, as a fire ant species, shows some predatory behavior towards earthworms and woodlice, and preys on the larvae of other ant species by tunneling into a neighboring colony’s brood chamber. This study focused on the molecular respon...

of 19

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Genes - ISSN 2073-4425