Table of Contents
Genes, Volume 10, Issue 6 (June 2019)
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Cover Story (view full-size image) Pet dogs are potentially the most powerful natural model for many human diseases, including cancer, [...] Read more. Pet dogs are potentially the most powerful natural model for many human diseases, including cancer, autoimmune disorders and psychiatric diseases (Image courtesy of Trish McMillan). In this issue, Megquier et al introduce the Barkbase data portal, a new epigenomic resource for dog research. Barkbase catalogs functional genomic regions in dozens of tissues from six adult dogs, who differed in ancestry, age, and size, as well as from embryos at four developmental time points. Modeled on similar resources in human genomics, this new portal supports efforts to identify and investigate canine genetic variants associated with traits and diseases. All data is freely accessible at barkbase.org with additional data in production. View this paper.