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Genes, Volume 10, Issue 1

January 2019 - 71 articles

Cover Story: How epigenetic Modifications (Mods) of small RNAs facilitate adaptation and the way back to homeostasis. This occurs all the way from bacteria (black bacilli from our gut loosing their pili) to humans (blue fellows raising their hands). View this paper.
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Articles (71)

  • Article
  • Open Access
4 Citations
4,525 Views
10 Pages

18 January 2019

Availability of diverse types of high-throughput data increases the opportunities for researchers to develop computational methods to provide a more comprehensive view for the mechanism and therapy of cancer. One fundamental goal for oncology is to d...

  • Article
  • Open Access
7 Citations
4,447 Views
20 Pages

17 January 2019

With the continuous accumulation of biological data, more and more machine learning algorithms have been introduced into the field of gene function prediction, which has great significance in decoding the secret of life. Recently, a multi-label super...

  • Article
  • Open Access
18 Citations
6,048 Views
25 Pages

17 January 2019

The GH3 gene family plays a vital role in the phytohormone-related growth and developmental processes. The effects of allopolyploidization on GH3 gene structures and expression levels have not been reported. In this study, a total of 38, 25, and 66 G...

  • Article
  • Open Access
40 Citations
8,582 Views
21 Pages

Cysteine-Rich Receptor-Like Kinase Gene Family Identification in the Phaseolus Genome and Comparative Analysis of Their Expression Profiles Specific to Mycorrhizal and Rhizobial Symbiosis

  • Elsa-Herminia Quezada,
  • Gabriel-Xicoténcatl García,
  • Manoj-Kumar Arthikala,
  • Govindappa Melappa,
  • Miguel Lara and
  • Kalpana Nanjareddy

17 January 2019

Receptor-like kinases (RLKs) are conserved upstream signaling molecules that regulate several biological processes, including plant development and stress adaptation. Cysteine (C)-rich receptor-like kinases (CRKs) are an important class of RLK that p...

  • Article
  • Open Access
12 Citations
6,083 Views
15 Pages

Functional Comparison of XPF Missense Mutations Associated to Multiple DNA Repair Disorders

  • Maria Marín,
  • María José Ramírez,
  • Miriam Aza Carmona,
  • Nan Jia,
  • Tomoo Ogi,
  • Massimo Bogliolo and
  • Jordi Surrallés

17 January 2019

XPF endonuclease is one of the most important DNA repair proteins. Encoded by XPF/ERCC4, XPF provides the enzymatic activity of XPF-ERCC1 heterodimer, an endonuclease that incises at the 5’ side of various DNA lesions. XPF is essential for nucl...

  • Article
  • Open Access
145 Citations
11,566 Views
16 Pages

17 January 2019

Rab family proteins play a crucial role in plant developmental processes and tolerance to environmental stresses. The current study investigated whether rice Rab7 (OsRab7) overexpression could improve rice tolerance to drought and heat stress conditi...

  • Review
  • Open Access
86 Citations
8,400 Views
27 Pages

Epitranscriptomic Signatures in lncRNAs and Their Possible Roles in Cancer

  • Sorina Dinescu,
  • Simona Ignat,
  • Andreea Daniela Lazar,
  • Carolina Constantin,
  • Monica Neagu and
  • Marieta Costache

16 January 2019

In contrast to the amazing exponential growth in knowledge related to long non-coding RNAs (lncRNAs) involved in cell homeostasis or dysregulated pathological states, little is known so far about the links between the chemical modifications occurring...

  • Review
  • Open Access
39 Citations
9,249 Views
17 Pages

Tuberculosis Genetic Epidemiology: A Latin American Perspective

  • Marc Woodman,
  • Ilsa L. Haeusler and
  • Louis Grandjean

16 January 2019

There are an estimated 10 million new cases of tuberculosis worldwide annually, with 282,000 new or relapsed cases each year reported from the Americas. With improvements in genome sequencing technology, it is now possible to study the genetic divers...

  • Article
  • Open Access
9 Citations
14,435 Views
17 Pages

Genomes of Three Closely Related Caribbean Amazons Provide Insight for Species History and Conservation

  • Sofiia Kolchanova,
  • Sergei Kliver,
  • Aleksei Komissarov,
  • Pavel Dobrinin,
  • Gaik Tamazian,
  • Kirill Grigorev,
  • Walter W. Wolfsberger,
  • Audrey J. Majeske,
  • Jafet Velez-Valentin and
  • Ricardo Valentin de la Rosa
  • + 6 authors

16 January 2019

Islands have been used as model systems for studies of speciation and extinction since Darwin published his observations about finches found on the Galapagos. Amazon parrots inhabiting the Greater Antillean Islands represent a fascinating model of sp...

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Genes - ISSN 2073-4425