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Cancers, Volume 16, Issue 8

April-2 2024 - 168 articles

Cover Story: Hepatocellular Carcinoma (HCC) is the third leading cause of cancer-related death and the sixth-most-diagnosed malignancy. Alpha-fetoprotein (AFP) is a traditional, ubiquitous biomarker. However, there increasing interest in using multiple biomarkers to optimize care. AFP, AFP-L3, and Prothrombin with vitamin K absence II (DCP) are useful, but have also established and significant limitations. ctDNA, genomic glycosylation, and even totally non-invasive salivary metabolomics/miRNA demonstrate great promise for both screening and surveillance, but lack large-scale prospective validation. We provide an update on the clinically available and emerging biomarkers for HCC, focusing on their respective clinical strengths and weaknesses. View this paper
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Articles (168)

  • Article
  • Open Access
1 Citations
2,277 Views
10 Pages

22 April 2024

Purpose: This study sought to investigate changes in quality of life (QoL) and symptom burden among palliative care patients undergoing one week of inpatient care in a specialized palliative care unit (PCU). The patient population was stratified into...

  • Review
  • Open Access
10 Citations
4,769 Views
35 Pages

An Overview of the Spices Used for the Prevention and Potential Treatment of Gastric Cancer

  • Katarzyna Kostelecka,
  • Łukasz Bryliński,
  • Olga Komar,
  • Justyna Michalczyk,
  • Agata Miłosz,
  • Jan Biłogras,
  • Filip Woliński,
  • Alicja Forma and
  • Jacek Baj

22 April 2024

Gastric cancer (GC) ranks third in terms of cancer-related deaths and is the fifth most commonly diagnosed type of cancer. Its risk factors include Helicobacter pylori infection, Epstein–Barr virus infection, the consumption of broiled and char...

  • Systematic Review
  • Open Access
4 Citations
5,169 Views
15 Pages

Imiquimod Is Effective in Reducing Cervical Intraepithelial Neoplasia: A Systematic Review and Meta-Analysis

  • Balázs Hamar,
  • Brigitta Teutsch,
  • Eszter Hoffmann,
  • Péter Hegyi,
  • Andrea Harnos,
  • Péter Nyirády,
  • Zsombor Hunka,
  • Nándor Ács,
  • Ferenc Bánhidy and
  • Zsolt Melczer

22 April 2024

Introduction: Topical Imiquimod is an immune response modifier approved for the off-label use of vulvar intraepithelial neoplasia. We conducted this systematic review and meta-analysis to investigate the efficacy and safety of Imiquimod in treating c...

  • Article
  • Open Access
6 Citations
5,824 Views
19 Pages

22 April 2024

Immunotherapy with PD-1/PD-L1 inhibitors has significantly improved the survival rates of patients with metastatic non-small-cell lung cancer (NSCLC). Results of a real-world data study investigating add-on VA (Viscum album L.) to chemotherapy have s...

  • Article
  • Open Access
3 Citations
2,824 Views
15 Pages

Effects of Adjuvant Exercise and Nutrition Therapy on Muscle Fibre Biomechanics in Gastrointestinal Cancer Patients

  • Michael Haug,
  • Raphaela Schwappacher,
  • Charlotte Pollmann,
  • Paul Ritter,
  • Mena Michael,
  • Hans Joachim Hermann,
  • Robert Grützmann,
  • Anke Mittelstädt,
  • Markus Friedrich Neurath and
  • Yurdagül Zopf
  • + 1 author

22 April 2024

Patients with aggressive cancer, e.g., gastrointestinal cancer, are prone (≥50% chance) to developing cancer cachexia (CC). Little is known about the effects of CC on the biomechanical function of muscle. A promising prevention strategy was found...

  • Article
  • Open Access
16 Citations
3,153 Views
20 Pages

Deferral of Treatment for Small Choroidal Melanoma and the Risk of Metastasis: An Investigation Using the Liverpool Uveal Melanoma Prognosticator Online (LUMPO)

  • Bertil Damato,
  • Antonio Eleuteri,
  • Azzam Taktak,
  • Rumana Hussain,
  • Maria Fili,
  • Gustav Stålhammar,
  • Heinrich Heimann and
  • Sarah E. Coupland

22 April 2024

Background: We estimated metastatic-death risk when the treatment of small choroidal melanomas is deferred until growth is observed. Methods: In 24 patients with choroidal melanoma (median diameter 5.85 mm), the exponential growth rate estimated by a...

  • Retraction
  • Open Access
8 Citations
1,722 Views
1 Page

22 April 2024

The Cancers Editorial Office retracts the article, “MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling” [...]

  • Article
  • Open Access
2 Citations
2,022 Views
12 Pages

Seroprevalence of SARS-CoV-2 and Hepatitis B Virus Coinfections among Ethiopians with Acute Leukemia

  • Jemal Alemu,
  • Balako Gumi,
  • Aster Tsegaye,
  • Ziyada Rahimeto,
  • Dessalegn Fentahun,
  • Fozia Ibrahim,
  • Abdulaziz Abubeker,
  • Amha Gebremedhin,
  • Tesfaye Gelanew and
  • Rawleigh Howe

22 April 2024

SARS-CoV-2 and blood-borne viral coinfections are well reported. Nevertheless, little is known regarding the seroprevalence of SARS-CoV-2 and coinfection with blood-borne viruses in hematologic malignancy patients in Ethiopia. We aimed to assess the...

  • Review
  • Open Access
3 Citations
3,481 Views
13 Pages

Immune Therapies in AL Amyloidosis—A Glimpse to the Future

  • Arnon Haran,
  • Iuliana Vaxman,
  • Moshe E. Gatt and
  • Eyal Lebel

22 April 2024

Light-chain (AL) amyloidosis is a rare plasma cell disorder characterized by the deposition of misfolded immunoglobulin light chains in target organs, leading to multi-organ dysfunction. Treatment approaches have historically mirrored but lagged behi...

  • Article
  • Open Access
3 Citations
2,902 Views
15 Pages

22 April 2024

Painful pelvic and spinal bone metastases are a considerable challenge for doctors and patients. Conventional therapies include morphine-equivalent medication (MeM) and local radiotherapy (RT), but these interventions are not always successful. More...

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Cancers - ISSN 2072-6694