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by
  • Richard A. Jacobson 1,
  • Emily Munding 1 and
  • Ashiq Masood 2,3,*
  • et al.

Reviewer 1: Anonymous Reviewer 2: Anonymous Reviewer 3: Anonymous

Round 1

Reviewer 1 Report

The authors have addressed my comments. Minor suggestions-

 

·        Lines 90-92: “CTCs are identified via nucleic acid amplification of mRNA for epithelial cellular adhesion molecule (EpCAM), carcinoembryonic antigen (CEA) or cytokeratin (16), or further immunolabeling of specific surface antigens”  -- consider reworking this sentence for accuracy

·        Line 309 typo: “on study”

·        Line 318 typo: “that CTCs”

 

Author Response

We appreciate reviewer's comments:

·        Lines 90-92: “CTCs are identified via nucleic acid amplification of mRNA for epithelial cellular adhesion molecule (EpCAM), carcinoembryonic antigen (CEA) or cytokeratin (16), or further immunolabeling of specific surface antigens”  -- consider reworking this sentence for accuracy

·        Line 309 typo: “on study”

·        Line 318 typo: “that CTCs”

 

All advised  edits have been made in this version of the manuscript.

 

Reviewer 2 Report

Well revised, acceptable for publication

Author Response

Thanks for the positive response. We appreciate taking time to review our manuscript.

Reviewer 3 Report

All previous concerns have been addressed.

Author Response

Thanks for the positive response. We appreciate taking time to review our manuscript.