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Micromachines, Volume 8, Issue 1

2017 January - 30 articles

Cover Story: In this communication, we demonstrate how a heat-sensitive adhesive material can be exploited to rapidly produce microfluidic devices for the three key stages of human profiling: DNA extraction, polymerase chain reaction, and DNA separation. These exemplary devices are equipped with the high levels of durability and resilience now expected by the end user in many applications, while the fabrication methodology itself presents characteristics which make it attractive as a prototyping tool. View this paper.
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Articles (30)

  • Article
  • Open Access
10 Citations
7,952 Views
13 Pages

Glass Imprint Templates by Spark Assisted Chemical Engraving for Microfabrication by Hot Embossing

  • Lucas Abia Hof,
  • Xin Guo,
  • Minseok Seo,
  • Rolf Wüthrich and
  • Jesse Greener

23 January 2017

As the field of microelectromechanical systems (MEMS) matures, new demands are being placed on the microfabrication of complex architectures in robust materials, such as hard plastics. Iterative design optimization in a timely manner—rapid prototypin...

  • Communication
  • Open Access
13 Citations
7,165 Views
8 Pages

22 January 2017

In this communication, we report a physical method for the fabrication of organic solvent and surfactant-resistant barriers on paper-based fluidic devices. When nonwoven polypropylene sheet is embossed with a steel mold, the embossed region acts as a...

  • Article
  • Open Access
50 Citations
9,280 Views
32 Pages

Microfluidic Techniques for Analytes Concentration

  • Cunlu Zhao,
  • Zhengwei Ge and
  • Chun Yang

22 January 2017

Microfluidics has been undergoing fast development in the past two decades due to its promising applications in biotechnology, medicine, and chemistry. Towards these applications, enhancing concentration sensitivity and detection resolution are indis...

  • Article
  • Open Access
11 Citations
5,800 Views
16 Pages

20 January 2017

The interaction of dielectrophoresis (DEP) particles in an electric field has been observed in many experiments, known as the “particle chains phenomenon”. However, the study in 3D models (spherical particles) is rarely reported due to its complexity...

  • Article
  • Open Access
45 Citations
8,270 Views
13 Pages

Human Liver Sinusoid on a Chip for Hepatitis B Virus Replication Study

  • Young Bok (Abraham) Kang,
  • Siddhartha Rawat,
  • Nicholas Duchemin,
  • Michael Bouchard and
  • Moses Noh

20 January 2017

We have developed a miniature human liver (liver-sinusoid-on-a-chip) model using a dual microchannel separated by a porous membrane. Primary human hepatocytes and immortalized bovine aortic endothelial cells were co-cultured on opposite sides of a mi...

  • Article
  • Open Access
12 Citations
6,940 Views
8 Pages

All-Semiconductor Plasmonic Resonator for Surface-Enhanced Infrared Absorption Spectroscopy

  • Wei Wei,
  • Jinpeng Nong,
  • Xiao Jiang,
  • Na Chen,
  • Suqin Luo and
  • Linlong Tang

19 January 2017

Infrared absorption spectroscopy remains a challenge due to the weak light-matter interaction between micron-wavelengthed infrared light and nano-sized molecules. A highly doped semiconductor supports intrinsic plasmon modes at infrared frequencies,...

  • Article
  • Open Access
22 Citations
6,967 Views
11 Pages

19 January 2017

This paper presents a sensitivity-enhanced gas sensor based on a film bulk acoustic resonator (FBAR). It was designed and fabricated with micro through-holes in its top electrode for sensitivity enhancement. The sensor was driven by a Colpitts oscill...

  • Article
  • Open Access
7 Citations
6,088 Views
13 Pages

Frequency-Dependent Electroformation of Giant Unilamellar Vesicles in 3D and 2D Microelectrode Systems

  • Qiong Wang,
  • Xiaoling Zhang,
  • Ting Fan,
  • Zhong Yang,
  • Xi Chen,
  • Zhenyu Wang,
  • Jie Xu,
  • Yuanyi Li,
  • Ning Hu and
  • Jun Yang

16 January 2017

A giant unilamellar vesicle (GUV), with similar properties to cellular membrane, has been widely studied. Electroformation with its simplicity and accessibility has become the most common method for GUV production. In this work, GUV electroformation...

  • Article
  • Open Access
90 Citations
11,443 Views
11 Pages

Effects of Process Conditions on the Mechanical Behavior of Aluminium Wrought Alloy EN AW-2219 (AlCu6Mn) Additively Manufactured by Laser Beam Melting in Powder Bed

  • Michael Cornelius Hermann Karg,
  • Bhrigu Ahuja,
  • Sebastian Wiesenmayer,
  • Sergey Vyacheslavovich Kuryntsev and
  • Michael Schmidt

16 January 2017

Additive manufacturing is especially suitable for complex-shaped 3D parts with integrated and optimized functionality realized by filigree geometries. Such designs benefit from low safety factors in mechanical layout. This demands ductile materials t...

  • Review
  • Open Access
127 Citations
21,764 Views
23 Pages

Droplet Microfluidics for the Production of Microparticles and Nanoparticles

  • Jianmei Wang,
  • Yan Li,
  • Xueying Wang,
  • Jianchun Wang,
  • Hanmei Tian,
  • Pei Zhao,
  • Ye Tian,
  • Yeming Gu,
  • Liqiu Wang and
  • Chengyang Wang

14 January 2017

Droplet microfluidics technology is recently a highly interesting platform in material fabrication. Droplets can precisely monitor and control entire material fabrication processes and are superior to conventional bulk techniques. Droplet production...

  • Article
  • Open Access
4 Citations
5,554 Views
12 Pages

13 January 2017

The piezoelectric micro-jet, which can achieve the drop-on-demand requirement, is based on ink-jet technology and small droplets can be ejected out by precise control. The droplets are driven out of the nozzle by the acoustic pressure waves which are...

  • Article
  • Open Access
8 Citations
6,655 Views
7 Pages

Solvent-Free Patterning of Colloidal Quantum Dot Films Utilizing Shape Memory Polymers

  • Hohyun Keum,
  • Yiran Jiang,
  • Jun Kyu Park,
  • Joseph C. Flanagan,
  • Moonsub Shim and
  • Seok Kim

10 January 2017

Colloidal quantum dots (QDs) with properties that can be tuned by size, shape, and composition are promising for the next generation of photonic and electronic devices. However, utilization of these materials in such devices is hindered by the limite...

  • Communication
  • Open Access
20 Citations
6,522 Views
8 Pages

Rapid Fabrication of Electrophoretic Microfluidic Devices from Polyester, Adhesives and Gold Leaf

  • Christopher Birch,
  • Jacquelyn A. DuVall,
  • Delphine Le Roux,
  • Brandon L. Thompson,
  • An-Chi Tsuei,
  • Jingyi Li,
  • Daniel A. Nelson,
  • Daniel L. Mills,
  • James P. Landers and
  • Brian E. Root

9 January 2017

In the last decade, the microfluidic community has witnessed an evolution in fabrication methodologies that deviate from using conventional glass and polymer-based materials. A leading example within this group is the print, cut and laminate (PCL) ap...

  • Communication
  • Open Access
18 Citations
7,948 Views
8 Pages

7 January 2017

In this paper we present a method to fabricate a fused silica microfluidic device by employing low viscosity KMPR photoresists. The resulting device is a continuous-flow microfluidic mixer based on hydrodynamic focusing. The advantages of this new fa...

  • Review
  • Open Access
47 Citations
10,695 Views
16 Pages

Towards Flexible Transparent Electrodes Based on Carbon and Metallic Materials

  • Minghui Luo,
  • Yanhua Liu,
  • Wenbin Huang,
  • Wen Qiao,
  • Yun Zhou,
  • Yan Ye and
  • Lin-Sen Chen

4 January 2017

Flexible transparent electrodes (FTEs) with high stability and scalability are in high demand for the extremely widespread applications in flexible optoelectronic devices. Traditionally, thin films of indium thin oxide (ITO) served the role of FTEs,...

  • Article
  • Open Access
13 Citations
6,343 Views
11 Pages

4 January 2017

We present a method based on a microfluidic chip that produces continuous jetting of alginate microfiber in the atmosphere to facilitate its collection and assembly. Through the analysis of the factors influencing the microfiber jetting, the principl...

  • Article
  • Open Access
5 Citations
6,751 Views
8 Pages

Time-Efficient High-Resolution Large-Area Nano-Patterning of Silicon Dioxide

  • Li Lin,
  • Yiyu Ou,
  • Martin Aagesen,
  • Flemming Jensen,
  • Berit Herstrøm and
  • Haiyan Ou

4 January 2017

A nano-patterning approach on silicon dioxide (SiO2) material, which could be used for the selective growth of III-V nanowires in photovoltaic applications, is demonstrated. In this process, a silicon (Si) stamp with nanopillar structures was first f...

  • Article
  • Open Access
2 Citations
5,612 Views
10 Pages

4 January 2017

In this paper, a silicon-based radio frequency micro-electromechanical systems (RF MEMS) pattern reconfigurable antenna for a Ka-band application was designed, analyzed, fabricated, and measured. The proposed antenna can steer the beam among three ra...

  • Review
  • Open Access
62 Citations
13,074 Views
26 Pages

Microfluidic Platform for Cell Isolation and Manipulation Based on Cell Properties

  • Caffiyar Mohamed Yousuff,
  • Eric Tatt Wei Ho,
  • Ismail Hussain K. and
  • Nor Hisham B. Hamid

4 January 2017

In molecular and cellular biological research, cell isolation and sorting are required for accurate investigation of a specific cell types. By employing unique cell properties to distinguish between cell types, rapid and accurate sorting with high ef...

  • Article
  • Open Access
38 Citations
5,686 Views
11 Pages

Tunable Clamped–Guided Arch Resonators Using Electrostatically Induced Axial Loads

  • Nouha Alcheikh,
  • Abdallah Ramini,
  • Md Abdullah Al Hafiz and
  • Mohammad I. Younis

4 January 2017

We present a simulation and experimental investigation of bi-directional tunable in-plane clamped–guided arch microbeam resonators. Tensile and compressive axial forces are generated from a bi-directional electrostatic actuator, which modulates the m...

  • Article
  • Open Access
4 Citations
6,211 Views
9 Pages

Preparation of Protein Nanoparticles Using NTA End Functionalized Polystyrenes on the Interface of a Multi-Laminated Flow Formed in a Microchannel

  • Hyeong Jin Jeon,
  • Chae Yeon Lee,
  • Moon Jeong Kim,
  • Xuan Don Nguyen,
  • Dong Hyeok Park,
  • Hyung Hoon Kim,
  • Jeung Sang Go and
  • Hyun-jong Paik

3 January 2017

This paper challenges the production of the protein nanoparticles using the conjugation of Ni2+ complexed nitrilotriacetic acid end-functionalized polystyrene (Ni-NTA-PS) and histidine tagged GFP (His-GFP) hybrid. The microfluidic synthesis of the pr...

  • Article
  • Open Access
2 Citations
5,898 Views
10 Pages

Microfluidic Separation of a Soluble Substance Using Transverse Diffusion in a Layered Flow

  • Xuan Don Nguyen,
  • Hyeong Jin Jeon,
  • Hyo Yong Kim,
  • Hyun Jong Paik,
  • June Huh,
  • Hyung Hoon Kim and
  • Jeung Sang Go

29 December 2016

This paper presents a practical flow-through method to separate anisole and ethyl phenylacetate, respectively, from a polystyrene mixture. The microfluidic separation uses different diffusive dynamics of the substances transverse to the lamination fl...

  • Feature Paper
  • Review
  • Open Access
63 Citations
16,782 Views
29 Pages

27 December 2016

Stretchable electronics represent a new generation of electronics that utilize soft, deformable elastomers as the substrate or matrix instead of the traditional rigid printed circuit boards. As the most essential component of stretchable electronics,...

  • Article
  • Open Access
4 Citations
5,065 Views
9 Pages

26 December 2016

In this study, a new type of temperature sensor device was developed. The circular electrode of the thermally sensitive sensor was modified with tetramethyltin (TMT) and O2 plasma to form a thin SnOxCy conductive layer on the electrode surface. The n...

  • Feature Paper
  • Review
  • Open Access
42 Citations
21,632 Views
25 Pages

Vorticella: A Protozoan for Bio-Inspired Engineering

  • Sangjin Ryu,
  • Rachel E. Pepper,
  • Moeto Nagai and
  • Danielle C. France

26 December 2016

In this review, we introduce Vorticella as a model biological micromachine for microscale engineering systems. Vorticella has two motile organelles: the oral cilia of the zooid and the contractile spasmoneme in the stalk. The oral cilia beat periodic...

  • Article
  • Open Access
29 Citations
8,784 Views
11 Pages

24 December 2016

Digital microfluidics (DMF) driven by electrowetting-on-dielectric (EWOD) has recently been attracting great attention as an effective liquid-handling platform for on-chip cooling. It enables rapid transportation of coolant liquid sandwiched between...

  • Article
  • Open Access
7 Citations
8,101 Views
12 Pages

MEMS Gyroscopes Based on Acoustic Sagnac Effect

  • Yuanyuan Yu,
  • Hao Luo,
  • Buyun Chen,
  • Jin Tao,
  • Zhihong Feng,
  • Hao Zhang,
  • Wenlan Guo and
  • Daihua Zhang

24 December 2016

This paper reports on the design, fabrication and preliminary test results of a novel microelectromechanical systems (MEMS) device—the acoustic gyroscope. The unique operating mechanism is based on the “acoustic version” of the Sagnac effect in fiber...

  • Article
  • Open Access
43 Citations
15,111 Views
15 Pages

A Microfluidic Chip for Cell Patterning Utilizing Paired Microwells and Protein Patterns

  • Chunlong Tu,
  • Bobo Huang,
  • Jian Zhou,
  • Yitao Liang,
  • Jian Tian,
  • Lin Ji,
  • Xiao Liang and
  • Xuesong Ye

23 December 2016

Cell patterning has been widely used in research on fundamental cell biology and in applications such as tissue engineering, neuron network formation, cell based biosensor and drug screening. Although various methods have been developed, cell pattern...

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Micromachines - ISSN 2072-666X