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Journal of Xenobiotics, Volume 12, Issue 3

September 2022 - 6 articles

Cover Story: Bisphenol A (BPA) is a widely used chemical in polycarbonate plastics and epoxy resins. However, its use is a growing concern since BPA is a hazardous compound. The endocrine-disrupting effects include actions on different functions at the cardiovascular level; however, its cardiotoxicity remains unclear. This work addresses the most recent studies regarding the hazardous effects of BPA exposure on the human cardiovascular system. Our findings demonstrated that BPA impairs cardiac excitability via the inhibition of ion channels, changes in Ca2+ handling, oxidative stress, and epigenetic modifications. Data support that BPA exposure increases the risk of developing cardiovascular diseases (CVD), including pregnancy disorders. In summary, BPA exposure compromises human health, promoting the development and progression of CVD and risk factors. View this paper
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Articles (6)

  • Review
  • Open Access
43 Citations
8,371 Views
30 Pages

2 September 2022

Pesticides are well known for their high levels of persistence and ubiquity in the environment, and because of their capacity to bioaccumulate and disrupt the food chain, they pose a risk to animals and humans. With a focus on organophosphate and tri...

  • Review
  • Open Access
33 Citations
6,721 Views
13 Pages

A Review of Methods for Removal of Ceftriaxone from Wastewater

  • Petro Karungamye,
  • Anita Rugaika,
  • Kelvin Mtei and
  • Revocatus Machunda

2 August 2022

The presence of pharmaceuticals in surface water and wastewater poses a threat to public health and has significant effects on the ecosystem. Since most wastewater treatment plants are ineffective at removing molecules efficiently, some pharmaceutica...

  • Review
  • Open Access
54 Citations
6,802 Views
9 Pages

Arsenic, Oxidative Stress and Reproductive System

  • Felor Zargari,
  • Md. Shiblur Rahaman,
  • Robab KazemPour and
  • Mahbobeh Hajirostamlou

18 July 2022

Infertility is a severe medical problem and is considered a serious global public health issue affecting a large proportion of humanity. Oxidative stress is one of the most crucial factors involved in infertility. Recent studies indicate that the ove...

  • Review
  • Open Access
65 Citations
11,967 Views
33 Pages

Endocrine-Disrupting Effects of Bisphenol A on the Cardiovascular System: A Review

  • Maria Inês Fonseca,
  • Margarida Lorigo and
  • Elisa Cairrao

13 July 2022

Currently, the plastic monomer and plasticizer bisphenol A (BPA) is one of the most widely used chemicals. BPA is present in polycarbonate plastics and epoxy resins, commonly used in food storage and industrial or medical products. However, the use o...

  • Review
  • Open Access
4 Citations
7,231 Views
23 Pages

Role of pH in Regulating Cancer Pyrimidine Synthesis

  • Saad Saeed Alqahtani,
  • Tomas Koltai,
  • Muntaser E. Ibrahim,
  • Adil H. H. Bashir,
  • Sari T. S. Alhoufie,
  • Samrein B. M. Ahmed,
  • Daria Di Molfetta,
  • Tiago M. A. Carvalho,
  • Rosa Angela Cardone and
  • Stephan Joel Reshkin
  • + 3 authors

6 July 2022

Replication is a fundamental aspect of cancer, and replication is about reproducing all the elements and structures that form a cell. Among them are DNA, RNA, enzymes, and coenzymes. All the DNA is doubled during each S (synthesis) cell cycle phase....

  • Review
  • Open Access
11 Citations
4,258 Views
13 Pages

28 June 2022

Since 1974, more than 800 disinfection byproducts (DBPs) have been identified from disinfected drinking water, swimming pool water, wastewaters, etc. Some DBPs are recognized as contaminants of high environmental concern because they may induce many...

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J. Xenobiot. - ISSN 2039-4713