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Thalassemia Reports
Volume 5
Issue 1
10.4081/thal.2015.4430
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Thalassemia Reports is published by MDPI from Volume 12 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Article

Screening of β-Thalassemia Trait among Pregnant Women with NESTROFT

by
Hitesh Sarda
,
Shankaran Rukmini Niveditha
* and
Nirmala Shivlingaiah
Shankaran Rukmini Niveditha, Department of Pathology, Kempegowda Institute of Medical Sciences, BSK 2nd Stage, Bangalore 560 070, Karnataka, India
*
Author to whom correspondence should be addressed.
Thalass. Rep. 2015, 5(1), 4430; https://doi.org/10.4081/thal.2015.4430
Submission received: 16 June 2014 / Revised: 5 November 2014 / Accepted: 28 January 2015 / Published: 10 March 2015

Abstract

The morbidity of β-thalassemia major has forced medical professionals to formulate screening tests to effectively screen β-thalassemia trait (BTT) of which naked eye single tube osmotic fragility test (NESTROFT) is the most cost effective test. Optimal time to screen for BTT appears to be during pregnancy, as at risk couples can be offered prenatal diagnosis. We screened 55 pregnant women attending antenatal clinic in a medical college hospital at Bangalore, with NESTROFT. Twelve (21.89%) were NESTROFT positive with mean hemoglobin of 11.2 mg % and packed cell volume of 32.6%. Catering predominantly to Vokkaliga community in whom literature reports increased prevalence of BTT, addition of a cost effective test like NESTROFT in the antenatal panel, appears promising.
Keywords: β-thalassemia trait; screening; NESTROFT; pregnancy β-thalassemia trait; screening; NESTROFT; pregnancy

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MDPI and ACS Style

Sarda, H.; Niveditha, S.R.; Shivlingaiah, N. Screening of β-Thalassemia Trait among Pregnant Women with NESTROFT. Thalass. Rep. 2015, 5, 4430. https://doi.org/10.4081/thal.2015.4430

AMA Style

Sarda H, Niveditha SR, Shivlingaiah N. Screening of β-Thalassemia Trait among Pregnant Women with NESTROFT. Thalassemia Reports. 2015; 5(1):4430. https://doi.org/10.4081/thal.2015.4430

Chicago/Turabian Style

Sarda, Hitesh, Shankaran Rukmini Niveditha, and Nirmala Shivlingaiah. 2015. "Screening of β-Thalassemia Trait among Pregnant Women with NESTROFT" Thalassemia Reports 5, no. 1: 4430. https://doi.org/10.4081/thal.2015.4430

APA Style

Sarda, H., Niveditha, S. R., & Shivlingaiah, N. (2015). Screening of β-Thalassemia Trait among Pregnant Women with NESTROFT. Thalassemia Reports, 5(1), 4430. https://doi.org/10.4081/thal.2015.4430

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