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Pediatric Reports
Volume 7
Issue 3
10.4081/pr.2015.5938
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Case Report

Recurrent Rhino-Ocular-Cerebral Mucormycosis in a Leukemic Child: A Case Report and Review of Pediatric Literature

by
Francesco De Leonardis
1,
Teresa Perillo
1,*,
Giuseppe Giudice
2,
Gianfranco Favia
3 and
Nicola Santoro
1
1
Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of Bari, Italy
2
Division of Plastic Surgery, University of Bari, Italy
3
Division of Otorinolaryngology, University of Bari, Italy
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2015, 7(3), 5938; https://doi.org/10.4081/pr.2015.5938
Submission received: 4 April 2015 / Revised: 26 June 2015 / Accepted: 26 June 2015 / Published: 28 September 2015

Abstract

Mucormycosis is an uncommon but severe fungal infection, typically observed in immunocompromized patients. We report a case of acute lymphoblastic leukemia complicated by rhino-oculo-cerebral mucormycosis in a pediatric patient. Combination lipid polyeneechinocandin therapy, along with surgical debridement appeared to be effective. Nevertheless, a severe relapse occurred during posaconazole prophylaxis; antifungal therapy, hemimaxillectomy and suspension of chemotherapy were performed. Although mucormycosis is a frequently lethal infection, prompt diagnosis and aggressive treatment can be successful even in cases of relapse.
Keywords: Mucormycosis; pediatrics; leukemia Mucormycosis; pediatrics; leukemia

Share and Cite

MDPI and ACS Style

De Leonardis, F.; Perillo, T.; Giudice, G.; Favia, G.; Santoro, N. Recurrent Rhino-Ocular-Cerebral Mucormycosis in a Leukemic Child: A Case Report and Review of Pediatric Literature. Pediatr. Rep. 2015, 7, 5938. https://doi.org/10.4081/pr.2015.5938

AMA Style

De Leonardis F, Perillo T, Giudice G, Favia G, Santoro N. Recurrent Rhino-Ocular-Cerebral Mucormycosis in a Leukemic Child: A Case Report and Review of Pediatric Literature. Pediatric Reports. 2015; 7(3):5938. https://doi.org/10.4081/pr.2015.5938

Chicago/Turabian Style

De Leonardis, Francesco, Teresa Perillo, Giuseppe Giudice, Gianfranco Favia, and Nicola Santoro. 2015. "Recurrent Rhino-Ocular-Cerebral Mucormycosis in a Leukemic Child: A Case Report and Review of Pediatric Literature" Pediatric Reports 7, no. 3: 5938. https://doi.org/10.4081/pr.2015.5938

APA Style

De Leonardis, F., Perillo, T., Giudice, G., Favia, G., & Santoro, N. (2015). Recurrent Rhino-Ocular-Cerebral Mucormycosis in a Leukemic Child: A Case Report and Review of Pediatric Literature. Pediatric Reports, 7(3), 5938. https://doi.org/10.4081/pr.2015.5938

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