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Pediatric Reports
Volume 6
Issue 3
10.4081/pr.2014.5619
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Case Report

Intraventricular Ciprofloxacin Usage in Treatment of Multidrug-Resistant Central Nervous System Infections: Report of Four Cases

by
Ayşe Karaaslan
,
Eda Kepenekli Kadayifçi
,
Ozden Turel
,
Demet Gedikbaşi Toprak
,
Ahmet Soysal
* and
Mustafa Bakir
Department of Pediatric Infectious Diseases, Marmara University School of Medicine, Istanbul, Turkey
*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2014, 6(3), 5619; https://doi.org/10.4081/pr.2014.5619
Submission received: 30 August 2014 / Revised: 11 October 2014 / Accepted: 8 November 2014 / Published: 12 December 2014

Abstract

In recent years, multidrug-resistant microorganisms appear as important nosocomial pathogens which treatment is quite difficult. As sufficient drug levels could not be achieved in cerebrospinal fluid during intravenous antibiotic therapy for central nervous system infections and due to multidrug-resistance treatment alternatives are limited. In this study, four cases of central nervous system infections due to multidrug-resistant microorganisms who were successfully treated with removal of the devices and intraventricular ciprofloxacin are presented. In conclusion, intraventricular ciprofloxacin can be used for treatment of central nervous system infections if the causative microorganism is sensitive to the drug and no other alternative therapy is available.
Keywords: intraventricular therapy; ciprofloxacin; children intraventricular therapy; ciprofloxacin; children

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MDPI and ACS Style

Karaaslan, A.; Kadayifçi, E.K.; Turel, O.; Toprak, D.G.; Soysal, A.; Bakir, M. Intraventricular Ciprofloxacin Usage in Treatment of Multidrug-Resistant Central Nervous System Infections: Report of Four Cases. Pediatr. Rep. 2014, 6, 5619. https://doi.org/10.4081/pr.2014.5619

AMA Style

Karaaslan A, Kadayifçi EK, Turel O, Toprak DG, Soysal A, Bakir M. Intraventricular Ciprofloxacin Usage in Treatment of Multidrug-Resistant Central Nervous System Infections: Report of Four Cases. Pediatric Reports. 2014; 6(3):5619. https://doi.org/10.4081/pr.2014.5619

Chicago/Turabian Style

Karaaslan, Ayşe, Eda Kepenekli Kadayifçi, Ozden Turel, Demet Gedikbaşi Toprak, Ahmet Soysal, and Mustafa Bakir. 2014. "Intraventricular Ciprofloxacin Usage in Treatment of Multidrug-Resistant Central Nervous System Infections: Report of Four Cases" Pediatric Reports 6, no. 3: 5619. https://doi.org/10.4081/pr.2014.5619

APA Style

Karaaslan, A., Kadayifçi, E. K., Turel, O., Toprak, D. G., Soysal, A., & Bakir, M. (2014). Intraventricular Ciprofloxacin Usage in Treatment of Multidrug-Resistant Central Nervous System Infections: Report of Four Cases. Pediatric Reports, 6(3), 5619. https://doi.org/10.4081/pr.2014.5619

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