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Neurology International, Volume 13, Issue 2

2021 June - 15 articles

Cover Story: When a uniform electric field develops within a cancer cell, polar molecules become subject to rotational forces, causing tubulin dimers and septin molecules to align with the electric field. This leads to a disruption of the spindle structure and mislocalization of the contractile apparatus. As a consequence, this can lead to membrane blebbing during anaphase, prolonged mitosis and mitotic cell death. It can also lead to abnormal DNA segregation between daughter cells and, eventually, cell death. View this paper.
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Articles (15)

  • Interesting Images
  • Open Access
9 Citations
3,072 Views
3 Pages

11 June 2021

Cardio-cerebral infarction, which refers to an acute ischemic stroke (AIS) and acute myocardial infarction (AMI) that occur concurrently, is an uncommon phenomenon with a grave prognosis. Intraluminal carotid thrombus (ICT) is an infrequently encount...

  • Review
  • Open Access
24 Citations
9,006 Views
14 Pages

Cenobamate, a Sodium Channel Inhibitor and Positive Allosteric Modulator of GABAA Ion Channels, for Partial Onset Seizures in Adults: A Comprehensive Review and Clinical Implications

  • Dustin R. Latimer,
  • Amber N. Edinoff,
  • Rachel D. Ruff,
  • Kelsey C. Rooney,
  • Kayla M. Penny,
  • Shaan B. Patel,
  • Suresh Sabbenahalli,
  • Adam M. Kaye,
  • Elyse M. Cornett and
  • Alan D. Kaye
  • + 2 authors

Medical management of epilepsy seeks to eliminate or to reduce the frequency of seizures, help patients maintain a normal lifestyle, and maintain psychosocial and occupational activities, while avoiding the negative side effects of long-term treatmen...

  • Case Report
  • Open Access
1 Citations
4,297 Views
12 Pages

Distinguishing between tumefactive demyelinating lesions (TDLs) and brain tumors in multiple sclerosis (MS) can be challenging. A progressive course is highly common with brain tumors in MS and no single neuroimaging technique is foolproof when disti...

  • Communication
  • Open Access
6 Citations
3,403 Views
8 Pages

Geriatric Neuro-Oncology in the Middle East: A Sultanate of Oman Experience

  • Omar Al-Taei,
  • Abdulrahman Al-Mirza and
  • Tariq Al-Saadi

Brain tumors are primary or metastatic malignancies of the central nervous system (CNS) with significant morbidity and mortality. The overall prevalence of cancer including brain cancer has increased by more than 10% according to the National Institu...

  • Article
  • Open Access
6 Citations
4,821 Views
8 Pages

The severity of Parkinson’s disease (PD) is developed by multifactorial factors. Falls can worsen disease severity. We previously found that frontal assessment battery (FAB) score was associated with a higher risk of future falls. This eight-year fol...

  • Review
  • Open Access
38 Citations
5,148 Views
17 Pages

Monomethyl Fumarate (MMF, Bafiertam) for the Treatment of Relapsing Forms of Multiple Sclerosis (MS)

  • Amnon A. Berger,
  • Emily R. Sottosanti,
  • Ariel Winnick,
  • Jonathan Izygon,
  • Kevin Berardino,
  • Elyse M. Cornett,
  • Alan D. Kaye,
  • Giustino Varrassi,
  • Omar Viswanath and
  • Ivan Urits

Multiple sclerosis (MS) is a prevalent neurologic autoimmune disorder affecting two million people worldwide. Symptoms include gait abnormalities, perception and sensory losses, cranial nerve pathologies, pain, cognitive dysfunction, and emotional ab...

  • Brief Report
  • Open Access
2 Citations
2,744 Views
5 Pages

Tinzaparin vs. Nadroparin Safety and Efficacy in Neurosurgery

  • Florian Wilhelmy,
  • Annika Hantsche,
  • Michael Gaier,
  • Johannes Kasper,
  • Michael Karl Fehrenbach,
  • Rene Oesemann,
  • Jürgen Meixensberger and
  • Dirk Lindner

Background: An outbreak of African swine fever (ASF) in China in 2020 has led to an unprecedented shortage of nadroparin. Most patients, especially those kept in hospital for surgery, are currently treated with prophylactic anticoagulation (AC). In s...

  • Article
  • Open Access
12 Citations
3,067 Views
7 Pages

Remodeling of the Posterior Cerebral Artery P1-Segment after Pipeline Flow Diverter Treatment of Posterior Communicating Artery Aneurysms

  • Miguel S. Litao,
  • Jan-Karl Burkhardt,
  • Omar Tanweer,
  • Eytan Raz,
  • Paul Huang,
  • Tibor Becske,
  • Maksim Shapiro,
  • Howard Riina and
  • Peter K. Nelson

Introduction: Flow diverters such as the pipeline embolization device (PED) cause hemodynamic changes of the treated vessel segment. In posterior communicating artery (PcomA), aneurysms’ unique anatomic consideration have to be taken in account due t...

  • Case Report
  • Open Access
3,225 Views
5 Pages

Fulminant Guillain–Barré Syndrome Post Hemorrhagic Stroke: Two Case Reports

  • Sameeh Abdulmana,
  • Naif Al-Zahrani,
  • Yahya Sharahely,
  • Shahid Bashir and
  • Talal M. Al-Harbi

Guillain–Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy characterized by ascending paralysis. Most GBS cases follow gastrointestinal or chest infections. Some patients have been reported either following or c...

  • Case Report
  • Open Access
1 Citations
4,296 Views
6 Pages

GRIN2A Variant in A 3-Year-Old—An Expanding Spectrum?

  • Ioana Gheța,
  • Raluca Ioana Teleanu,
  • Eugenia Roza,
  • Evelina Carapancea,
  • Oana Vladacenco and
  • Daniel Mihai Teleanu

29 April 2021

Glutamate, the major excitatory neurotransmitter, plays a ubiquitous role in most aspects of normal brain functioning. Its indispensable position is paradoxically doubled by a high excitotoxic potential following disruption of its dynamic equilibrium...

  • Review
  • Open Access
2 Citations
3,850 Views
9 Pages

A Unique Case of Bilateral Thalamic High-Grade Glioma in a Pediatric Patient with LI-Fraumeni Syndrome: Case Presentation and Review of the Literature

  • Raffaella Messina,
  • Gerardo Cazzato,
  • Teresa Perillo,
  • Vita Stagno,
  • Valeria Blè,
  • Mariachiara Resta,
  • Francesco De Leonardis,
  • Nicola Santoro,
  • Francesco Signorelli and
  • Giuseppe Ingravallo

22 April 2021

Li-Fraumeni syndrome (LFS) is a rare high-penetrance and autosomal-dominant pathological condition caused by the germline mutation of the TP53 gene, predisposing to the development of tumors from pediatric age. We conducted a qualitative systematic r...

  • Article
  • Open Access
2 Citations
2,727 Views
9 Pages

15 April 2021

Background and Aims: Nerve conduction study (NCS) measures how fast an electrical impulse moves through the nerve and is a standard technique for diagnosing and assessing neurological diseases. Despite diabetes and obesity being a common accompanimen...

  • Review
  • Open Access
15 Citations
7,363 Views
15 Pages

Tumor-Treating Fields Therapy for Pediatric Brain Tumors

  • Atsushi Makimoto,
  • Ryo Nishikawa,
  • Keita Terashima,
  • Jun Kurihara,
  • Hiroyuki Fujisaki,
  • Satoshi Ihara,
  • Yoshihiko Morikawa and
  • Yuki Yuza

8 April 2021

Tumor-treating fields (TTFields) are alternating electric fields applied continuously to the brain by attaching two-pair arrays on the scalp. Although TTFields therapy has demonstrated efficacy against supratentorial glioblastoma (GBM) in adults, its...

  • Case Report
  • Open Access
12 Citations
5,317 Views
8 Pages

SCN8A Encephalopathy: Case Report and Literature Review

  • Hueng-Chuen Fan,
  • Hsiu-Fen Lee and
  • Ching-Shiang Chi

1 April 2021

Epileptic encephalopathy is a condition resulting from extreme forms of intractable childhood epilepsy. The disease can cause severe delays in cognitive, sensory, and motor function development, in addition to being fatal in some cases. Missense muta...

  • Brief Report
  • Open Access
8 Citations
6,118 Views
13 Pages

Overcoming the Elusiveness of Neurosarcoidosis: Learning from Five Complex Cases

  • Parissa Feizi,
  • Medha Tandon,
  • Erum Khan,
  • Roshan Subedi,
  • Apoorv Prasad,
  • Anisa Chowdhary and
  • Shitiz Sriwastava

25 March 2021

The involvement of the central nervous system in sarcoidosis can manifest with a variety of neurological symptoms, and most of them can be nonspecific. The diagnosis of neurosarcoidosis (NS) can therefore be very challenging without a tissue biopsy....

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Neurol. Int. - ISSN 2035-8377