Identification of a Novel Human Rhinovirus C Type by Antibody Capture VIDISCA-454
AbstractCausative agents for more than 30 percent of respiratory infections remain unidentified, suggesting that unknown respiratory pathogens might be involved. In this study, antibody capture VIDISCA-454 (virus discovery cDNA-AFLP combined with Roche 454 high-throughput sequencing) resulted in the discovery of a novel type of rhinovirus C (RV-C). The virus has an RNA genome of at least 7054 nt and carries the characteristics of rhinovirus C species. The gene encoding viral protein 1, which is used for typing, has only 81% nucleotide sequence identity with the closest known RV-C type, and, therefore, the virus represents the first member of a novel type, named RV-C54. View Full-Text
Share & Cite This Article
Jazaeri Farsani, S.M.; Oude Munnink, B.B.; Canuti, M.; Deijs, M.; Cotten, M.; Jebbink, M.F.; Verhoeven, J.; Kellam, P.; Loens, K.; Goossens, H.; Ieven, M.; van der Hoek, L. Identification of a Novel Human Rhinovirus C Type by Antibody Capture VIDISCA-454. Viruses 2015, 7, 239-251.
Jazaeri Farsani SM, Oude Munnink BB, Canuti M, Deijs M, Cotten M, Jebbink MF, Verhoeven J, Kellam P, Loens K, Goossens H, Ieven M, van der Hoek L. Identification of a Novel Human Rhinovirus C Type by Antibody Capture VIDISCA-454. Viruses. 2015; 7(1):239-251.Chicago/Turabian Style
Jazaeri Farsani, Seyed Mohammad; Oude Munnink, Bas B.; Canuti, Marta; Deijs, Martin; Cotten, Matthew; Jebbink, Maarten F.; Verhoeven, Joost; Kellam, Paul; Loens, Katherine; Goossens, Herman; Ieven, Margareta; van der Hoek, Lia. 2015. "Identification of a Novel Human Rhinovirus C Type by Antibody Capture VIDISCA-454." Viruses 7, no. 1: 239-251.