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Hematology ReviewsHematology Reviews
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10 November 2009

2 Pages

Massive Pleural Effusion Due to IgG Multiple Myeloma

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and
1
Department of Haematology, Wycombe General Hospital, High Wycombe HP11 2TT, UK
2
Department of Trauma and Orthopaedics, Royal London Hospital, Whitechapel, London E1 1BB, UK
*
Author to whom correspondence should be addressed.
Hematol. Rev.2009, 1(2), e18;https://doi.org/10.4081/hr.2009.e18 
(registering DOI)

Abstract

Pleural effusion directly attributable to multiple myeloma is exceedingly uncommon and is said to occur in only 1–2% of cases. Of these around 80% occur in IgA disease. We report a case of myelomatous pleural effusion (proven on cytological and immunohistochemical analysis) in a patient with the IgG-k subtype. We describe the diagnosis, pathogenesis and management of this condition and show the radiological and cytological evidence of the case.

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