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Pathophysiology, Volume 32, Issue 4

December 2025 - 22 articles

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Articles (22)

  • Review
  • Open Access
121 Views
34 Pages

Lifestyle-Based Approaches to Cancer Prevention and Treatment: Diet, Physical Activity, and Integrative Strategies

  • Gianpiero Greco,
  • Alessandro Petrelli,
  • Francesco Fischetti and
  • Stefania Cataldi

Cancer remains a leading global cause of morbidity and mortality. Modifiable lifestyle factors, including avoidance of tobacco use and excessive ultraviolet radiation, healthy dietary patterns, regular physical activity, and weight management, play k...

  • Correction
  • Open Access
112 Views
1 Page

Correction: Al-Barazenji et al. Association Between Vitamin D Receptor BsmI Polymorphism and Low Bone Mineral Density in Postmenopausal Women in the MENA Region. Pathophysiology 2025, 32, 6

  • Tara Al-Barazenji,
  • Asma Allouch,
  • Nedhal Al Husaini,
  • Sondos Yousef,
  • Wisam Nabeel Ibrahim,
  • Amal Al-Haidose,
  • Hatem Zayed and
  • Atiyeh M. Abdallah

In the original publication [...]

  • Article
  • Open Access
310 Views
13 Pages

Neuromuscular Electrical Stimulation Plus Nutritional Counseling Attenuates Thigh Muscle Thickness Loss in Hospitalized Cancer Patients

  • Tatyanne L. N. Gomes,
  • Thaís C. Borges,
  • Jessica F. M. Ivo,
  • Lara G. Mainardi,
  • Renata G. C. Abadio,
  • Benjamin T. Wall and
  • Gustavo D. Pimentel

Background and aims: This study aimed to determine whether neuromuscular electrical stimulation (NMES) combined with nutritional counseling promotes an increase in thigh muscle thickness (MT), as well as to assess changes in the relationship between...

  • Article
  • Open Access
214 Views
14 Pages

Objectives: This study investigates the effects of resveratrol on systemic inflammatory, oxidative, and metabolic responses in a rat model that combines surgical trauma with prior exposure to Single Prolonged Stress (SPS), an established experimental...

  • Article
  • Open Access
385 Views
14 Pages

Calcification in Vascular Smooth Muscle Cells Is Associated with Elevated GCLm and Impaired Contraction: Insights into Osteogenic Transdifferentiation and Therapeutic Approaches

  • Luisa F. Delgadillo,
  • Nabil A. Rashdan,
  • Hunter Hamilton,
  • Jack H. Pattillo,
  • Shuai Yuan,
  • Randa S. Eshaq,
  • Norman R. Harris,
  • Jonathan S. Alexander and
  • Christopher B. Pattillo

Background: Vascular calcification is a strong predictor of cardiovascular morbidity and mortality. Oxidative stress plays a key role in promoting vascular calcification. Glutathione (GSH), as a major cellular antioxidant, is produced in response to...

  • Feature Paper
  • Article
  • Open Access
406 Views
11 Pages

Introduction: The prognosis for patients admitted to emergency departments (ED) after drowning or diving accidents is often uncertain. In this study, we evaluated a range of clinical and laboratory parameters as potential indicators of survival. Many...

  • Article
  • Open Access
564 Views
23 Pages

Objectives: Serum ferritin (SF) reflects iron homeostasis, in addition to being an acute phase reactant protein. Since its levels are altered in the obesity state, we compared body composition, metabolic profile, liver alterations, and dietary patter...

  • Article
  • Open Access
424 Views
12 Pages

Diffusion Tensor Tractography Shows White Matter Tract Changes in Breast Cancer Survivors with Balance Impairment

  • Alexandra Nikolaeva,
  • Maria Pospelova,
  • Mark Voynov,
  • Varvara Krasnikova,
  • Albina Makhanova,
  • Samvel Tonyan,
  • Aleksandr Efimtsev,
  • Fionik Olga,
  • Anatoliy Levchuk and
  • Gennadiy Trufanov
  • + 4 authors

Objectives: Breast cancer survivors often experience long-term neurological complications, including balance impairments, following treatment. This study aimed to investigate microstructural changes in white matter tracts in breast cancer survivors w...

  • Article
  • Open Access
357 Views
11 Pages

Increased Mortality with Intermediate Ascitic Polymorphonuclear Cell Counts Amongst Patients with Cirrhosis: Time to Redefine the Care Approach

  • Shahid Habib,
  • Michael Ball,
  • Chris Thomas,
  • Traci Murakami,
  • Nehali Patel,
  • Sandeep Yarlagadda,
  • Sarah Patel,
  • Courtney Walker,
  • Varun Takyar and
  • Krunal Patel
  • + 2 authors

Background: Spontaneous bacterial peritonitis (SBP) is a serious complication in patients with decompensated cirrhosis and ascites. Diagnosis typically relies on an ascitic polymorphonuclear (A-PMN) cell count ≥ 250 cells/high-power field (HPF). M...

  • Review
  • Open Access
1,880 Views
23 Pages

Systemic lupus erythematosus is a multifactorial autoimmune disease characterized by the dysregulation of both innate and adaptive immunity, resulting in chronic inflammation, autoantibody production, and multi-organ damage. Innate immune dysfunction...

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Pathophysiology - ISSN 1873-149X